Search Results - "Kamocka, Malgorzata"

A practical guide to evaluating colocalization in biological microscopy by Dunn, Kenneth W, Kamocka, Malgorzata M, McDonald, John H

“…Fluorescence microscopy is one of the most powerful tools for elucidating the cellular functions of proteins and other molecules. In many cases, the function…”
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Longitudinal intravital microscopy of the mouse kidney: inflammatory responses to abdominal imaging windows by Martinez, Michelle M, Walsh, Julia R, Kamocka, Malgorzata M, Lee, Hyowon, Dunn, Kenneth W

“…Intravital microscopy enables direct observation of cell biology and physiology at subcellular resolution in real time in living animals. Implanted windows…”
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Triple Antibiotic Polymer Nanofibers for Intracanal Drug Delivery: Effects on Dual Species Biofilm and Cell Function by Pankajakshan, Divya, PhD, Albuquerque, Maria T.P., DDS, MSD, PhD, Evans, Joshua D., BS, DDS, Kamocka, Malgorzata M., PhD, Gregory, Richard L., PhD, Bottino, Marco C., DDS, MSc, PhD

“…Abstract Introduction Root canal disinfection and the establishment of an intracanal microenvironment conducive to the proliferation/differentiation of stem…”
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Epigenetic basis of diabetic vasculopathy by Bhamidipati, Theja, Kumar, Manishekhar, Verma, Sumit S, Mohanty, Sujit K, Kacar, Sedat, Reese, Diamond, Martinez, Michelle M, Kamocka, Malgorzata M, Dunn, Kenneth W, Sen, Chandan K, Singh, Kanhaiya

“…Type 2 diabetes mellitus (T2DM) causes peripheral vascular disease because of which several blood-borne factors, including vital nutrients fail to reach the…”
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A Multiscale Model of Venous Thrombus Formation with Surface-Mediated Control of Blood Coagulation Cascade by Xu, Zhiliang, Lioi, Joshua, Mu, Jian, Kamocka, Malgorzata M., Liu, Xiaomin, Chen, Danny Z., Rosen, Elliot D., Alber, Mark

“…A combination of the extended multiscale model, new image processing algorithms, and biological experiments is used for studying the role of Factor VII (FVII)…”
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VEGFR3 tyrosine kinase inhibition aggravates cisplatin nephrotoxicity by Black, Laurence M, Farrell, Elisa R, Barwinska, Daria, Osis, Gunars, Zmijewska, Anna A, Traylor, Amie M, Esman, Stephanie K, Bolisetty, Subhashini, Whipple, Grace, Kamocka, Malgorzata M, Winfree, Seth, Spangler, Daryll R, Khan, Shehnaz, Zarjou, Abolfazl, El-Achkar, Tarek M, Agarwal, Anupam

“…Expansion of renal lymphatic networks, or lymphangiogenesis (LA), is well recognized during development and is now being implicated in kidney diseases…”
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A multiscale model of thrombus development by Xu, Zhiliang, Chen, Nan, Kamocka, Malgorzata M, Rosen, Elliot D, Alber, Mark

“…A two-dimensional multiscale model is introduced for studying formation of a thrombus (clot) in a blood vessel. It involves components for modelling viscous,…”
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Neuropeptide Y regulates a vascular gateway for hematopoietic stem and progenitor cells by Singh, Pratibha, Hoggatt, Jonathan, Kamocka, Malgorzata M, Mohammad, Khalid S, Saunders, Mary R, Li, Hongge, Speth, Jennifer, Carlesso, Nadia, Guise, Theresa A, Pelus, Louis M

“…Endothelial cells (ECs) are components of the hematopoietic microenvironment and regulate hematopoietic stem and progenitor cell (HSPC) homeostasis. Cytokine…”
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Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival by Logsdon, Derek P., Shah, Fenil, Carta, Fabrizio, Supuran, Claudiu T., Kamocka, Malgorzata, Jacobsen, Max H., Sandusky, George E., Kelley, Mark R., Fishel, Melissa L.

“…Pancreatic ductal adenocarcinoma (PDAC) has reactive stroma that promotes tumor signaling, fibrosis, inflammation, and hypoxia, which activates HIF-1α to…”
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A Versatile, Portable Intravital Microscopy Platform for Studying Beta-cell Biology In Vivo by Reissaus, Christopher A., Piñeros, Annie R., Twigg, Ashley N., Orr, Kara S., Conteh, Abass M., Martinez, Michelle M., Kamocka, Malgorzata M., Day, Richard N., Tersey, Sarah A., Mirmira, Raghavendra G., Dunn, Kenneth W., Linnemann, Amelia K.

“…The pancreatic islet is a complex micro-organ containing numerous cell types, including endocrine, immune, and endothelial cells. The communication of these…”
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Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways by Bijangi-Vishehsaraei, Khadijeh, Reza Saadatzadeh, M, Wang, Haiyan, Nguyen, Angie, Kamocka, Malgorzata M, Cai, Wenjing, Cohen-Gadol, Aaron A, Halum, Stacey L, Sarkaria, Jann N, Pollok, Karen E, Safa, Ahmad R

“…OBJECTIVE Defects in the apoptotic machinery and augmented survival signals contribute to drug resistance in glioblastoma (GBM). Moreover, another complexity…”
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Factor VIII trafficking to CD4+ T cells shapes its immunogenicity and requires several types of antigen-presenting cells by Kaczmarek, Radoslaw, Piñeros, Annie R., Patterson, Paige E., Bertolini, Thais B., Perrin, George Q., Sherman, Alexandra, Born, Jameson, Arisa, Sreevani, Arvin, Matthew C., Kamocka, Malgorzata M., Martinez, Michelle M., Dunn, Kenneth W., Quinn, Sean M., Morris, Johnathan J., Wilhelm, Amelia R., Kaisho, Tsuneyasu, Munoz-Melero, Maite, Biswas, Moanaro, Kaplan, Mark H., Linnemann, Amelia K., George, Lindsey A., Camire, Rodney M., Herzog, Roland W.

“…•Helper T-cell response to coagulation factor VIII critically depends on a select set of anatomically distinct antigen-presenting cells.•Innate immune…”
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Quantitative 3-dimensional imaging and tissue cytometry reveals lymphatic expansion in acute kidney injury by Black, Laurence M., Winfree, Seth, Khochare, Suraj D., Kamocka, Malgorzata M., Traylor, Amie M., Esman, Stephanie K., Khan, Shehnaz, Zarjou, Abolfazl, Agarwal, Anupam, El-Achkar, Tarek M.

“…The lymphatic system plays an integral role in physiology and has recently been identified as a key player in disease progression. Tissue injury stimulates…”
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CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche by Chitteti, Brahmananda Reddy, Kobayashi, Michihiro, Cheng, Yinghua, Zhang, Huajia, Poteat, Bradley A., Broxmeyer, Hal E., Pelus, Louis M., Hanenberg, Helmut, Zollman, Amy, Kamocka, Malgorzata M., Carlesso, Nadia, Cardoso, Angelo A., Kacena, Melissa A., Srour, Edward F.

“…We previously showed that immature CD166+ osteoblasts (OB) promote hematopoietic stem cell (HSC) function. Here, we demonstrate that CD166 is a functional HSC…”
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Two-photon intravital imaging of thrombus development by Kamocka, Malgorzata, Mu, Jian, Liu, Xiaomin, Chen, Nan, Zollman, Amy, Sturonas-Brown, Barbara, Dunn, Kenneth, Xu, Zhiliang, Chen, Danny Z, Alber, Mark S, Rosen, Elliot D

“…Thrombus development in mouse mesenteric vessels following laser-induced injury was monitored by high-resolution, near-real-time, two-photon, intravital…”
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Quantification of Lymphangiogenesis in the Murine Lymphedema Tail Model Using Intravital Microscopy by Mohan, Ganesh, Khan, Imran, Diaz, Stephanie M, Kamocka, Malgorzata M, Hulsman, Luci A, Ahmed, Shahnur, Neumann, Colby R, Jorge, Miguel D, Gordillo, Gayle M, Sen, Chandan K, Sinha, Mithun, Hassanein, Aladdin H

“…Lymphedema is chronic limb swelling resulting from lymphatic dysfunction. It affects an estimated five million Americans. There is no cure for this disease…”
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Intravital imaging of the kidney in a rat model of salt-sensitive hypertension by Endres, Bradley T, Sandoval, Ruben M, Rhodes, George J, Campos-Bilderback, Silvia B, Kamocka, Malgorzata M, McDermott-Roe, Christopher, Staruschenko, Alexander, Molitoris, Bruce A, Geurts, Aron M, Palygin, Oleg

“…Hypertension is one of the most prevalent diseases worldwide and a major risk factor for renal failure and cardiovascular disease. The role of albuminuria, a…”
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Applying Small Molecule Signal Transducer and Activator of Transcription-3 (STAT3) Protein Inhibitors as Pancreatic Cancer Therapeutics by Arpin, Carolyn C, Mac, Stephen, Jiang, Yanlin, Cheng, Huiwen, Grimard, Michelle, Page, Brent D G, Kamocka, Malgorzata M, Haftchenary, Sina, Su, Han, Ball, Daniel P, Rosa, David A, Lai, Ping-Shan, Gómez-Biagi, Rodolfo F, Ali, Ahmed M, Rana, Rahul, Hanenberg, Helmut, Kerman, Kagan, McElyea, Kyle C, Sandusky, George E, Gunning, Patrick T, Fishel, Melissa L

“…Constitutively activated STAT3 protein has been found to be a key regulator of pancreatic cancer and a target for molecular therapeutic intervention. In this…”
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ST2 as checkpoint target for colorectal cancer immunotherapy by Van der Jeught, Kevin, Sun, Yifan, Fang, Yuanzhang, Zhou, Zhuolong, Jiang, Hua, Yu, Tao, Yang, Jinfeng, Kamocka, Malgorzata M, So, Ka Man, Li, Yujing, Eyvani, Haniyeh, Sandusky, George E, Frieden, Michael, Braun, Harald, Beyaert, Rudi, He, Xiaoming, Zhang, Xinna, Zhang, Chi, Paczesny, Sophie, Lu, Xiongbin

“…Immune checkpoint blockade immunotherapy delivers promising clinical results in colorectal cancer (CRC). However, only a fraction of cancer patients develop…”
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Combining RNAi and in vivo confocal microscopy analysis of the photoconvertible fluorescent protein Dendra2 to study a DNA repair protein by Tell, Gianluca, Di Piazza, Matteo, Kamocka, Malgorzata M, Vascotto, Carlo

“…Clinical approaches for tumor treatment often rely on combination therapy where a DNA damaging agent is used in combination with a DNA repair protein…”
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