Search Results - "Kammari, Kurumurthy"
-
1
The topoisomerase II β -kinase associated with HIV-1 is a potential target for pyridine-bischalcones' anti-HIV-1 activity
Published in European journal of medicinal chemistry (05-11-2023)“…Topoisomerase II (TopoII) is a critical component of HIV-1 integration, proviral DNA synthesis, and reverse transcription. During HIV-1 infection, the…”
Get full text
Journal Article -
2
Discovery of dual cation-π inhibitors of acetylcholinesterase: design, synthesis and biological evaluation
Published in Pharmacological reports (01-06-2020)“…Alzheimer's disease (AD) is a widespread dementia-related disease affecting mankind worldwide. A cholinergic hypothesis is considered the most effective target…”
Get more information
Journal Article -
3
Development of pyridine dicoumarols as potent anti HIV-1 leads, targeting HIV-1 associated topoisomeraseIIβ kinase
Published in Future medicinal chemistry (01-09-2017)“…A structural study of a series of pyridine dicoumarol derivatives with potential activity against a novel Topoisomerase IIβ kinase which was identified in the…”
Get full text
Journal Article -
4
Epoxydicoumarin Derivative is a Novel Non‐Nucleoside TLR8 Agonist: Screening, Synthesis and Biological Evaluation
Published in ChemistrySelect (Weinheim) (28-06-2021)“…Toll‐like receptors (TLRs) activate host innate immunity by recognizing microbial ligands and viral nucleic acids. Of late, TLR8 has emerged as an attractive…”
Get full text
Journal Article