Search Results - "Kaminski, Sandra"

Simulated Microgravity Disrupts Nuclear Factor κB Signaling and Impairs Murine Dendritic Cell Phenotype and Function by Calcagno, Gaetano, Jeandel, Jeremy, Frippiat, Jean-Pol, Kaminski, Sandra

“…During spaceflights, astronauts face different forms of stress (e.g., socio-environmental and gravity stresses) that impact physiological functions and…”
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Chronic Hypergravity Induces a Modification of Histone H3 Lysine 27 Trimethylation at TCRβ Locus in Murine Thymocytes by Calcagno, Gaetano, Ouzren, Nassima, Kaminski, Sandra, Ghislin, Stéphanie, Frippiat, Jean-Pol

“…Gravity changes are major stressors encountered during spaceflight that affect the immune system. We previously evidenced that hypergravity exposure during…”
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Link between the EZH2 noncanonical pathway and microtubule organization center polarization during early T lymphopoiesis by Deshayes, Frederique, Fradet, Magali, Kaminski, Sandra, Viguier, Mireille, Frippiat, Jean-Pol, Ghislin, Stephanie

“…EZH2 plays an essential role at the β-selection checkpoint of T lymphopoiesis by regulating histone H3 lysine 27 trimethylation (H3K27me3) via its canonical…”
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Lipolysis-Stimulated Lipoprotein Receptor Acts as Sensor to Regulate ApoE Release in Astrocytes by Herzine, Ameziane, Sekkat, Ghita, Kaminski, Sandra, Calcagno, Gaetano, Boschi-Muller, Sandrine, Safi, Hela, Corbier, Catherine, Siest, Sophie, Claudepierre, Thomas, Yen, Frances T.

“…Astroglia play an important role, providing de novo synthesized cholesterol to neurons in the form of ApoE-lipidated particles; disruption of this process can…”
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Modulation of Iberian Ribbed Newt Complement Component C3 by Stressors Similar to those Encountered during a Stay Onboard the International Space Station by Guéguinou, Nathan, Jeandel, Jérémy, Kaminski, Sandra, Baatout, Sarah, Ghislin, Stéphanie, Frippiat, Jean-Pol

“…The complement system plays an important role in inflammation, innate and acquired immunity, as well as homeostasis. Despite these functions, the effects of…”
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The Nuclear Orphan Receptor NR2F6 Is a Central Checkpoint for Cancer Immune Surveillance by Hermann-Kleiter, Natascha, Klepsch, Victoria, Wallner, Stephanie, Siegmund, Kerstin, Klepsch, Sebastian, Tuzlak, Selma, Villunger, Andreas, Kaminski, Sandra, Pfeifhofer-Obermair, Christa, Gruber, Thomas, Wolf, Dominik, Baier, Gottfried

“…Nuclear receptor subfamily 2, group F, member 6 (NR2F6) is an orphan member of the nuclear receptor superfamily. Here, we show that genetic ablation of Nr2f6…”
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Targeted Suppression of Lipoprotein Receptor LSR in Astrocytes Leads to Olfactory and Memory Deficits in Mice by El Hajj, Aseel, Herzine, Ameziane, Calcagno, Gaetano, Désor, Frédéric, Djelti, Fathia, Bombail, Vincent, Denis, Isabelle, Oster, Thierry, Malaplate, Catherine, Vigier, Maxime, Kaminski, Sandra, Pauron, Lynn, Corbier, Catherine, Yen, Frances T, Lanhers, Marie-Claire, Claudepierre, Thomas

“…Perturbations of cholesterol metabolism have been linked to neurodegenerative diseases. Glia-neuron crosstalk is essential to achieve a tight regulation of…”
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The potent protein kinase C-selective inhibitor AEB071 (sotrastaurin) represents a new class of immunosuppressive agents affecting early T-cell activation by Evenou, Jean-Pierre, Wagner, Jürgen, Zenke, Gerhard, Brinkmann, Volker, Wagner, Kathrin, Kovarik, Jiri, Welzenbach, Karl A, Weitz-Schmidt, Gabriele, Guntermann, Christine, Towbin, Harry, Cottens, Sylvain, Kaminski, Sandra, Letschka, Thomas, Lutz-Nicoladoni, Christina, Gruber, Thomas, Hermann-Kleiter, Natascha, Thuille, Nikolaus, Baier, Gottfried

“…There is a pressing need for immunosuppressants with an improved safety profile. The search for novel approaches to blocking T-cell activation led to the…”
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Starch-Based Foam Packaging Developed from a By-Product of Potato Industrialization (Solanum tuberosum L.) by Rodrigues, Nathalie Hamine Panzarini, de Souza, Jovani Taveira, Rodrigues, Reinaldo Luan, Canteri, Maria Helene Giovanetti, Tramontin, Sandra Mara Kaminski, de Francisco, Antonio Carlos

“…The use of petroleum-based packaging and its disposal in the environment poses several environmental problems, driving research into the development of…”
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PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes by Thuille, Nikolaus, Wachowicz, Katarzyna, Hermann-Kleiter, Natascha, Kaminski, Sandra, Fresser, Friedrich, Lutz-Nicoladoni, Christina, Leitges, Michael, Thome, Margot, Massoumi, Ramin, Baier, Gottfried

“…In T cells PKCθ mediates the activation of critical signals downstream of TCR/CD28 stimulation. We investigated the molecular mechanisms by which PKCθ…”
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The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis by Kaminski, Sandra, Adjali, Oumeya, Jacquet, Chantal, Garaude, Johan, Keriel, Anne, Lassaux, Adeline, Hipskind, Robert, Sitbon, Marc, Taylor, Naomi, Villalba, Martin

“…Vav1 is expressed exclusively in hematopoietic cells and is required for T cell development and activation. Vav1-deficient mice show thymic hypocellularity due…”
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Simulated Microgravity Disrupts Nuclear Factor kB Signaling and Impairs Murine Dendritic Cell Phenotype and Function by Calcagno, Gaetano, Jeandel, Jeremy, Frippiat, Jean-Pol, Kaminski, Sandra

“…During spaceflights, astronauts face different forms of stress (e.g., socio-environmental and gravity stresses) that impact physiological functions and…”
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Prospects of apoptotic cell-based therapies for transplantation and inflammatory diseases by Saas, Philippe, Kaminski, Sandra, Perruche, Sylvain

“…Apoptotic cell removal or interactions of early-stage apoptotic cells with immune cells are associated with an immunomodulatory microenvironment that can be…”
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Socioenvironmental stressors encountered during spaceflight partially affect the murine TCR‐β repertoire and increase its self‐reactivity by Fonte, Coralie, Kaminski, Sandra, Vanet, Anne, Lanfumey, Laurence, Cohen-Salmon, Charles, Ghislin, Stéphanie, Frippiat, Jean-Pol

“…ABSTRACT Spaceflights are known to affect the immune system. In a previous study, we demonstrated that hypergravity exposure during murine development modified…”
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Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response by Harlé, Guillaume, Kaminski, Sandra, Dubayle, David, Frippiat, Jean-Pol, Ropars, Armelle

“…Chronic stress is now recognized as a risk factor for disease development and/or exacerbation. It has been shown to affect negatively the immune system and…”
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Hypergravity exposure during gestation modifies the TCRβ repertoire of newborn mice by Ghislin, Stéphanie, Ouzren-Zarhloul, Nassima, Kaminski, Sandra, Frippiat, Jean-Pol

“…During spaceflight, organisms are subjected to mechanical force changes (gravity (G) changes) that affect the immune system. However, gravitational effects on…”
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Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response by Harlé, Guillaume, Kaminski, Sandra, Dubayle, David, Frippiat, Jean-Pol, Ropars, Armelle

“…Chronic stress is now recognized as a risk factor for disease development and/or exacerbation. It has been shown to affect negatively the immune system and…”
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The Kinase PKCα Selectively Upregulates Interleukin-17A during Th17 Cell Immune Responses by Meisel, Marlies, Hermann-Kleiter, Natascha, Hinterleitner, Reinhard, Gruber, Thomas, Wachowicz, Katarzyna, Pfeifhofer-Obermair, Christa, Fresser, Friedrich, Leitges, Michael, Soldani, Cristiana, Viola, Antonella, Kaminski, Sandra, Baier, Gottfried

“…Transforming growth-factor β (TGFβ) has been implicated in T helper 17 (Th17) cell biology and in triggering expression of interleukin-17A (IL-17A), which is a…”
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Apoptotic cell-induced tolerance implicates pdc and shapes adaptive immunity (P1100) by Perruche, Sylvain, Bonnefoy, Francis, Kaminski, Sandra, Saas, Philippe

“…Abstract Plasmacytoid dendritic cells (pDC) are involved in innate immune response to viral infection. They can mount a strong anti-viral response with the…”
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The Nuclear Orphan Receptor NR2F6 Suppresses Lymphocyte Activation and T Helper 17-Dependent Autoimmunity by Hermann-Kleiter, Natascha, Gruber, Thomas, Lutz-Nicoladoni, Christina, Thuille, Nikolaus, Fresser, Friedrich, Labi, Verena, Schiefermeier, Natalia, Warnecke, Marei, Huber, Lukas, Villunger, Andreas, Eichele, Gregor, Kaminski, Sandra, Baier, Gottfried

“…The protein kinase C (PKC) family of serine-threonine kinases plays a central role in T lymphocyte activation. Here, we identify NR2F6, a nuclear zinc-finger…”
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