Search Results - "Kamileri, Irene"

Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks by Sotiriou, Sotirios K., Kamileri, Irene, Lugli, Natalia, Evangelou, Konstantinos, Da-Ré, Caterina, Huber, Florian, Padayachy, Laura, Tardy, Sebastien, Nicati, Noemie L., Barriot, Samia, Ochs, Fena, Lukas, Claudia, Lukas, Jiri, Gorgoulis, Vassilis G., Scapozza, Leonardo, Halazonetis, Thanos D.

“…Human cancers are characterized by the presence of oncogene-induced DNA replication stress (DRS), making them dependent on repair pathways such as…”
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R-spondin 1 and noggin facilitate expansion of resident stem cells from non-damaged gallbladders by Lugli, Natalia, Kamileri, Irene, Keogh, Adrian, Malinka, Thomas, Sarris, Michalis E, Talianidis, Iannis, Schaad, Olivier, Candinas, Daniel, Stroka, Deborah, Halazonetis, Thanos D

“…Pioneering studies within the last few years have allowed the in vitro expansion of tissue‐specific adult stem cells from a variety of endoderm‐derived organs,…”
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DNA Damage Triggers a Chronic Autoinflammatory Response, Leading to Fat Depletion in NER Progeria by Karakasilioti, Ismene, Kamileri, Irene, Chatzinikolaou, Georgia, Kosteas, Theodoros, Vergadi, Eleni, Robinson, Andria Rasile, Tsamardinos, Iannis, Rozgaja, Tania A., Siakouli, Sandra, Tsatsanis, Christos, Niedernhofer, Laura J., Garinis, George A.

“…Lipodystrophies represent a group of heterogeneous disorders characterized by loss of fat tissue. However, the underlying mechanisms remain poorly understood…”
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A mouse model of accelerated liver aging caused by a defect in DNA repair by Gregg, Siobhán Q., Gutiérrez, Verónica, Rasile Robinson, Andria, Woodell, Tyler, Nakao, Atsunori, Ross, Mark A., Michalopoulos, George K., Rigatti, Lora, Rothermel, Carrie E., Kamileri, Irene, Garinis, George A., Beer Stolz, Donna, Niedernhofer, Laura J.

“…The liver changes with age, leading to an impaired ability to respond to hepatic insults and increased incidence of liver disease in the elderly. Therefore,…”
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POLD3 Is Haploinsufficient for DNA Replication in Mice by Murga, Matilde, Lecona, Emilio, Kamileri, Irene, Díaz, Marcos, Lugli, Natalia, Sotiriou, Sotirios K., Anton, Marta E., Méndez, Juan, Halazonetis, Thanos D., Fernandez-Capetillo, Oscar

“…The Pold3 gene encodes a subunit of the Polδ DNA polymerase complex. Pold3 orthologs are not essential in Saccharomyces cerevisiae or chicken DT40 cells, but…”
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Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria by Kamileri, Irene, Karakasilioti, Ismene, Sideri, Aria, Kosteas, Theodoros, Tatarakis, Antonis, Talianidis, Iannis, Garinis, George A

“…Nucleotide excision repair (NER) defects are associated with cancer, developmental disorders and neurodegeneration. However, with the exception of cancer, the…”
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Enhanced Rate of Acquisition of Point Mutations in Mouse Intestinal Adenomas Compared to Normal Tissue by Lugli, Natalia, Dionellis, Vasilis S., Ordóñez-Morán, Paloma, Kamileri, Irene, Sotiriou, Sotirios K., Huelsken, Joerg, Halazonetis, Thanos D.

“…The most prevalent single-nucleotide substitution (SNS) found in cancers is a C-to-T substitution in the CpG motif. It has been proposed that many of these…”
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Nucleotide excision repair: new tricks with old bricks by Kamileri, Irene, Karakasilioti, Ismene, Garinis, George A

“…Nucleotide excision repair (NER) is a major DNA repair pathway that ensures that the genome remains functionally intact and is faithfully transmitted to…”
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DNA damage triggers a chronic auto-inflammatory response leading to fat depletion in NER progeria by Karakasilioti, Ismene, Kamileri, Irene, Chatzinikolaou, Georgia, Kosteas, Theodoros, Vergadi, Eleni, Robinson, Andria Rasile, Tsamardinos, Iannis, Rozgaja, Tania A, Siakouli, Sandra, Tsatsanis, Christos, Niedernhofer, Laura J., Garinis, George A.

“…Lipodystrophies represent a group of heterogeneous disorders characterized by loss of fat tissue. However, the underlying mechanisms remain poorly understood…”
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A mouse model of accelerated liver aging due to a defect in DNA repair by Gregg, Siobhán Q., Gutiérrez, Verónica, Robinson, Andria Rasile, Woodell, Tyler, Nakao, Atsunori, Ross, Mark A., Michalopoulos, George K., Rigatti, Lora, Rothermel, Carrie E., Kamileri, Irene, Garinis, George, Stolz, Donna Beer, Niedernhofer, Laura J.

“…The liver changes with age leading to an impaired ability to respond to hepatic insults and increased incidence of liver disease in the elderly. Therefore,…”
Get full text