Search Results - "Kamijo, Seiji"

Staphylococcus aureus membrane and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes through the Toll-like receptor 2–Toll-like receptor 6 pathway by Vu, Anh Tuan, MD, PhD, Baba, Tadashi, PhD, Chen, Xue, MD, Le, Tuan Anh, MD, PhD, Kinoshita, Hirokazu, MD, PhD, Xie, Yang, MD, Kamijo, Seiji, PhD, Hiramatsu, Keiichi, MD, PhD, Ikeda, Shigaku, MD, PhD, Ogawa, Hideoki, MD, PhD, Okumura, Ko, MD, PhD, Takai, Toshiro, PhD

“…Background Staphylococcus aureus heavily colonizes the lesions of patients with atopic dermatitis (AD) and is known to trigger a worsening of AD. However, the…”
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IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation by Kamijo, Seiji, Takeda, Haruna, Tokura, Tomoko, Suzuki, Mayu, Inui, Kyoko, Hara, Mutsuko, Matsuda, Hironori, Matsuda, Akira, Oboki, Keisuke, Ohno, Tatsukuni, Saito, Hirohisa, Nakae, Susumu, Sudo, Katsuko, Suto, Hajime, Ichikawa, Saori, Ogawa, Hideoki, Okumura, Ko, Takai, Toshiro

“…How the innate and adaptive immune systems cooperate in the natural history of allergic diseases has been largely unknown. Plant-derived allergen, papain, and…”
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Epicutaneous Allergic Sensitization by Cooperation between Allergen Protease Activity and Mechanical Skin Barrier Damage in Mice by Shimura, Sakiko, Takai, Toshiro, Iida, Hideo, Maruyama, Natsuko, Ochi, Hirono, Kamijo, Seiji, Nishioka, Izumi, Hara, Mutsuko, Matsuda, Akira, Saito, Hirohisa, Nakae, Susumu, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku

“…Allergen sources such as mites, insects, fungi, and pollen contain proteases. Airway exposure to proteases induces allergic airway inflammation and IgE/IgG1…”
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Airway inflammation after epicutaneous sensitization of mice requires protease activity of low-dose allergen inhalation by Nishioka, Izumi, Takai, Toshiro, Maruyama, Natsuko, Kamijo, Seiji, Suchiva, Punyada, Suzuki, Mayu, Kunimine, Shinya, Ochi, Hirono, Shimura, Sakiko, Sudo, Katsuko, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku

“…Recent studies demonstrated that antigen-specific ST2+ but not ST2− memory TH2 cells were responsible for airway eosinophilia in mice8 and also that IL-33…”
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TSLP expression induced via Toll-like receptor pathways in human keratinocytes by Takai, Toshiro, Chen, Xue, Xie, Yang, Vu, Anh Tuan, Le, Tuan Anh, Kinoshita, Hirokazu, Kawasaki, Junko, Kamijo, Seiji, Hara, Mutsuko, Ushio, Hiroko, Baba, Tadashi, Hiramatsu, Keiichi, Ikeda, Shigaku, Ogawa, Hideoki, Okumura, Ko

“…The skin epidermis and mucosal epithelia (airway, ocular tissues, gut, and so on) are located at the interface between the body and environment and have…”
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Innate basophil IL-4 responses against allergens, endotoxin, and cytokines require the Fc receptor γ-chain by Kamijo, Seiji, PhD, Nunomura, Satoshi, PhD, Ra, Chisei, MD, PhD, Kanaguchi, Yasuhiko, MD, PhD, Suzuki, Yusuke, MD, PhD, Ogawa, Hideoki, MD, PhD, Okumura, Ko, MD, PhD, Takai, Toshiro, PhD

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Presensitization to Ascaris antigens promotes induction of mite-specific IgE upon mite antigen inhalation in mice by Suzuki, Mayu, Hara, Mutsuko, Ichikawa, Saori, Kamijo, Seiji, Nakazawa, Takuya, Hatanaka, Hideki, Akiyama, Kazuo, Ogawa, Hideoki, Okumura, Ko, Takai, Toshiro

“…Patients with house dust mite (HDM) allergy or Ascariasis produce serum IgE specific to the antigens of HDM or nematode Ascaris, respectively. Although human…”
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Involvement of TNF-Like Weak Inducer of Apoptosis in the Pathogenesis of Collagen-Induced Arthritis by Kamata, Koichi, Kamijo, Seiji, Nakajima, Atsuo, Koyanagi, Akemi, Kurosawa, Hisashi, Yagita, Hideo, Okumura, Ko

“…TNF-like weak inducer of apoptosis (TWEAK) is a type II membrane protein belonging to the TNF family that regulates apoptotic cell death, cellular…”
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Antigen Protease Activity on Intact or Tape-Stripped Skin Induces Acute Itch and T Helper Sensitization Leading to Airway Eosinophilia in Mice by Kimitsu, Toru, Kamijo, Seiji, Yoshimura, Tomoko, Masutani, Yurie, Shimizu, Saya, Takada, Keiko, Suchiva, Punyada, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku, Takai, Toshiro

“…Respiratory allergen sources such as house dust mites frequently contain proteases. In this study, we demonstrated that the epicutaneous application of a model…”
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Epicutaneous Administration of Papain Induces IgE and IgG Responses in a Cysteine Protease Activity-Dependent Manner by Iida, Hideo, Takai, Toshiro, Hirasawa, Yusuke, Kamijo, Seiji, Shimura, Sakiko, Ochi, Hirono, Nishioka, Izumi, Maruyama, Natsuko, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku

“…[ABSTRACT] Background: Epicutaneous sensitization to allergens is important in the pathogenesis of not only skin inflammation such as atopic dermatitis but…”
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Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA by Kinoshita, Hirokazu, MD, Takai, Toshiro, PhD, Anh Le, Tuan, MD, Kamijo, Seiji, PhD, Ling Wang, Xiao, MD, Ushio, Hiroko, DVM, PhD, Hara, Mutsuko, BSc, Kawasaki, Junko, MD, Tuan Vu, Anh, MD, Ogawa, Takasuke, MD, Gunawan, Hendra, MD, PhD, Ikeda, Shigaku, MD, PhD, Okumura, Ko, MD, PhD, Ogawa, Hideoki, MD, PhD

“…Background Thymic stromal lymphopoietin (TSLP) plays a key role in allergic diseases, such as atopic dermatitis (AD) and asthma. TSLP is highly expressed by…”
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Cupressaceae Pollen Grains Modulate Dendritic Cell Response and Exhibit IgE-Inducing Adjuvant Activity In Vivo by Kamijo, Seiji, Takai, Toshiro, Kuhara, Takatoshi, Tokura, Tomoko, Ushio, Hiroko, Ota, Mikiko, Harada, Norihiro, Ogawa, Hideoki, Okumura, Ko

“…Pollen is considered a source of not only allergens but also immunomodulatory substances, which could play crucial roles in sensitization and/or the…”
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NADPH oxidase activity in allergenic pollen grains of different plant species by Wang, Xiao-Ling, Takai, Toshiro, Kamijo, Seiji, Gunawan, Hendra, Ogawa, Hideoki, Okumura, Ko

“…Pollen is an important trigger of allergic diseases. Recent studies have shown that ragweed pollen NAD(P)H oxidase generates reactive oxygen species (ROS) and…”
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Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody by Kamijo, Seiji, Nakajima, Atsuo, Ikeda, Kaori, Aoki, Kazuhiro, Ohya, Keiichi, Akiba, Hisaya, Yagita, Hideo, Okumura, Ko

“…Receptor activator of NF-κB (RANK) and its ligand (RANKL) are pivotal regulators of osteoclast differentiation. RANK and RANKL also mediate T cell/dendritic…”
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Characterization of proteases, proteins, and eicosanoid-like substances in soluble extracts from allergenic pollen grains by Gunawan, Hendra, Takai, Toshiro, Kamijo, Seiji, Wang, Xiao Ling, Ikeda, Shigaku, Okumura, Ko, Ogawa, Hideoki

“…Pollen is an important trigger of seasonal rhinitis, conjunctivitis, and/or allergic asthma, and an exacerbating factor in atopic dermatitis. Pollen grains…”
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Visualization of Antigen-specific T Cell in Living Arthritic Mice by Nakajima, Atsuo, Kamijo, Seiji, Yoshioka, Taro

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Antigen Protease Activity with a Detergent Induces Severe Skin Inflammation with Itch and Robust T Helper 17/T Helper 22 Differentiation in Mice by Yoshimura, Tomoko, Kamijo, Seiji, Ichikawa, Saori, Kimitsu, Toru, Masutani, Yurie, Shimizu, Saya, Takada, Keiko, Ogawa, Takasuke, Tominaga, Mitsutoshi, Takamori, Kenji, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku, Takai, Toshiro

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Epicutaneous vaccination with protease inhibitor-treated papain prevents papain-induced Th2-mediated airway inflammation without inducing Th17 in mice by Kunimine, Shinya, Takai, Toshiro, Kamijo, Seiji, Maruyama, Natsuko, Kimitsu, Toru, Masutani, Yurie, Yoshimura, Tomoko, Suchiva, Punyada, Shimizu, Saya, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku

“…Environmental allergen sources such as house dust mites contain proteases, which are frequently allergens themselves. Inhalation with the exogenous proteases,…”
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Cyclooxygenase inhibition in mice heightens adaptive‐ and innate‐type responses against inhaled protease allergen and IL‐33 by Maruyama, Natsuko, Takai, Toshiro, Kamijo, Seiji, Suchiva, Punyada, Ohba, Mai, Takeshige, Tomohito, Suzuki, Mayu, Hara, Mutsuko, Matsuno, Kei, Harada, Sonoko, Harada, Norihiro, Nakae, Susumu, Sudo, Katsuko, Okuno, Toshiaki, Yokomizo, Takehiko, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku

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Skin Treatment with Detergent Promotes Protease Allergen-Dependent Epicutaneous Sensitization in a Manner Different from Tape Stripping in Mice by Ochi, Hirono, Takai, Toshiro, Shimura, Sakiko, Maruyama, Natsuko, Nishioka, Izumi, Kamijo, Seiji, Iida, Hideo, Nakae, Susumu, Ogawa, Hideoki, Okumura, Ko, Ikeda, Shigaku

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