Search Results - "Kamigaso, Shunsuke"

Preclinical metabolism and the disposition of vornorexant/TS‐142, a novel dual orexin 1/2 receptor antagonist for the treatment of insomnia by Konno, Yoshihiro, Kamigaso, Shunsuke, Toki, Hidetoh, Terasaka, Shuichi, Hikichi, Hirohiko, Endo, Hiromi, Yamaguchi, Jun‐Ichi, Mizuno‐Yasuhira, Akiko

“…We investigated the metabolism and disposition of vornorexant, a novel dual orexin receptor antagonist, in rats and dogs, and clarified in vitro metabolite…”
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Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model by Inoue, Katsuhisa, Nakai, Yasuhiro, Ueda, Sayaka, Kamigaso, Shunsuke, Ohta, Kin-ya, Hatakeyama, Mai, Hayashi, Yayoi, Otagiri, Masaki, Yuasa, Hiroaki

“…Proton-coupled folate transporter/heme carrier protein 1 (PCFT/HCP1) has recently been identified as a transporter that mediates the translocation of folates…”
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Identification of 2-[2-(4-tert-Butylphenyl)ethyl]-N-[4-(3-cyclopentylpropyl)-2-fluorophenyl]-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide as an Orally Active MGAT2 Inhibitor by Busujima, Tsuyoshi, Tanaka, Hiroaki, Iwakiri, Kanako, Shirasaki, Yoshihisa, Munetomo, Eiji, Saito, Masako, Masuko, Aiko, Kitano, Kiyokazu, Io, Fusayo, Kato, Koji, Kamigaso, Shunsuke, Nozoe, Akiko, Sato, Nagaaki

“…We previously reported 2-[2-(4-tert-butylphenyl)ethyl]-N-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide 2 as on orally available…”
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Lead generation from N-[benzyl(4-phenylbutyl)carbamoyl]amino acid as a novel LPA1 antagonist for the treatment of systemic sclerosis by Kobayashi, Yuki, Uneuchi, Fumito, Naruse, Takumi, Matsuda, Daisuke, Okumura-Kitajima, Lisa, Kajiyama, Hiromitsu, Wada, Reiko, Yonemoto, Yuki, Nakano, Koichiro, Toki, Hidetoh, Kamigaso, Shunsuke, Yamagishi, Jyunya, Tokura, Seiken, Kakinuma, Hiroyuki, Kuroda, Shoichi

“…Lysophosphatidic acid (LPA), a bioactive phospholipid, binds to the G protein-coupled LPA1 receptor on the surfaces of immune cells, to promote progression of…”
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Lead generation from N-benzyl(4-phenylbutyl)carbamoylamino acid as a novel LPA1 antagonist for the treatment of systemic sclerosis by Kobayashi, Yuki, Uneuchi, Fumito, Naruse, Takumi, Matsuda, Daisuke, Okumura-Kitajima, Lisa, Kajiyama, Hiromitsu, Wada, Reiko, Yonemoto, Yuki, Nakano, Koichiro, Toki, Hidetoh, Kamigaso, Shunsuke, Yamagishi, Jyunya, Tokura, Seiken, Kakinuma, Hiroyuki, Kuroda, Shoichi

“…Lysophosphatidic acid (LPA), a bioactive phospholipid, binds to the G protein-coupled LPA1 receptor on the surfaces of immune cells, to promote progression of…”
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