Search Results - "Kamholz, J."

Transcranial direct current stimulation (tDCS) for the treatment of a Multiple Sclerosis symptom cluster by Workman, C.D., Kamholz, J., Rudroff, T.

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Increased thalamic activity and less neuropathic pain after tDCS observed with PET in a patient with multiple sclerosis: A case report by Rudroff, T., Proessl, F., Kamholz, J., Ponto, L.L.

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Phenotypic clustering in MPZ mutations by Shy, Michael E., Jáni, Agnes, Krajewski, Karen, Grandis, Marina, Lewis, Richard A., Li, Jun, Shy, Rosemary R., Balsamo, Janne, Lilien, Jack, Garbern, James Y., Kamholz, John

“…Myelin protein zero (MPZ) is a member of the immunoglobulin gene superfamily with single extracellular, transmembrane and cytoplasmic domains. Homotypic…”
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Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation by GARBERN, James Y, YOOL, Donald A, SHY, Michael E, KAMHOLZ, John A, GRIFFITHS, Ian R, MOORE, Gregory J, WILDS, Ian B, FAULK, Michael W, KLUGMANN, Matthias, NAVE, Klaus-Amin, SISTERMANS, Erik A, VAN DER KNAAP, Marjo S, BIRD, Thomas D

“…Axonal degeneration contributes to clinical disability in the acquired demyelinating disease multiple sclerosis. Axonal degeneration occurs during acute…”
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Neurological dysfunction and axonal degeneration in Charcot–Marie–Tooth disease type 1A by Krajewski, Karen M., Lewis, Richard A., Fuerst, Darren R., Turansky, Cheryl, Hinderer, Steven R., Garbern, James, Kamholz, John, Shy, Michael E.

“…Charcot–Marie–Tooth disease type 1A (CMT1A), the most frequent form of CMT, is caused by a 1.5 Mb duplication on the short arm of chromosome 17. Patients with…”
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Skin biopsies demonstrate MPZ splicing abnormalities in Charcot-Marie-Tooth neuropathy 1B by SABET, A, LI, J, GHANDOUR, K, PU, Q, WU, X, KAMHOLZ, J, SHY, M. E, CAMBI, F

“…To demonstrate that intronic mutations in the myelin protein zero (MPZ) cause Charcot-Marie-Tooth neuropathy 1B (CMT1B) by disrupting MPZ splicing. We report a…”
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Charcot-Marie-Tooth disease type 1: Molecular pathogenesis to gene therapy by KAMHOLZ, J, MENICHELLA, D, JANI, A, GARBERN, J, LEWIS, R. A, KRAJEWSKI, K. M, LILIEN, J, SCHERER, S. S, SHY, M. E

“…Charcot-Marie-Tooth disease type 1 (CMT1) is caused by mutations in the peripheral myelin protein, 22 kDa (PMP22) gene, protein zero (P0) gene, early growth…”
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P174 Transcranial Direct Current Stimulation (tDCS) with 2 mA and 4 mA for the treatment of a multiple sclerosis symptom cluster – A pilot study by Workman, C., Kamholz, J., Rudroff, T.

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Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiation by Tang, X-M., Beesley, J.S., Grinspan, J.B., Seth, P., Kamholz, J., Cambi, F.

“…Oligodendrocyte differentiation is accompanied by dramatic changes in gene expression as well as cell cycle arrest. To determine whether cell cycle arrest is…”
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Evidence That the Homeodomain Protein Gtx Is Involved in the Regulation of Oligodendrocyte Myelination by Awatramani, Raj, Scherer, Steven, Grinspan, Judith, Collarini, Ellen, Skoff, Robert, O'Hagan, David, Garbern, James, Kamholz, John

“…We have investigated the patterns of postnatal brain expression and DNA binding of Gtx, a homeodomain transcription factor. Gtx mRNA accumulates in parallel…”
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Axon-Schwann cell interactions regulate the expression of c-jun in Schwann cells by Shy, M.E., Shi, Y., Wrabetz, L., Kamholz, J., Scherer, S.S.

“…The transcription factor c‐jun is selectively expressed by non‐myelinating Schwann cells in normal peripheral nerve, and by “denervated,” previously…”
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Expression of growth-associated protein-43 kD in Schwann cells is regulated by axon-Schwann cell interactions and cAMP by Scherer, S S, Xu, Y T, Roling, D, Wrabetz, L, Feltri, M L, Kamholz, J

“…We have examined the regulation of growth-associated protein 43 kD (GAP-43) in rat Schwann cells. In unlesioned adult nerves, GAP-43-immunoreactivity was…”
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Regulation of myelin development by Kamholz, J A

“…During the final stage of oligodendrocyte differentiation, oligodendrocyte precursors cease proliferating, and coordinately activate the set of genes encoding…”
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Molecular analysis of the 18q- syndrome : and correlation with phenotype by KLINE, A. D, WHITE, M. E, WAPNER, R, ROJAS, K, BIESECKER, L. G, KAMHOLZ, J, ZACKAI, E. H, MUENKE, M, SCOTT, C. I, OVERHAUSER, J

“…Seven individuals with deletions of the distal long arm of chromosome 18 were evaluated at the clinical, cytogenetic, and molecular levels. The patients had…”
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Evidence for neuroaxonal injury in patients with proteolipid gene mutations by Garbern, J, Shy, M, Krajewski, K, Kamholz, J, Hobson, G, Cambi, F

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Identification of Three Forms of Human Myelin Basic Protein by cDNA Cloning by Kamholz, John, De Ferra, Francesca, Puckett, Carmie, Lazzarini, Robert

“…We have isolated cDNA clones encoding three separate forms of human myelin basic protein (MBP), 21.5, 18.5, and 17.2 kDa, and have determined the nucleotide…”
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Organization and expression of the human myelin basic protein gene by Kamholz, J, Toffenetti, J, Lazzarini, R A

“…The human brain contains four isoforms of myelin basic protein (MBP), previously identified by cDNA cloning. We have now isolated and characterized genomic…”
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Double-stranded RNA unwinding and modifying activity is detected ubiquitously in primary tissues and cell lines by WAGNER, R. W, YOO, C, NISHIKURA, K, WRABETZ, L, KAMHOLZ, J, BUCCHALTER, J, HASSAN, N. F, KHALILI, K, KIM, S. U, PERUSSIA, B, MCMORRIS, F. A

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Axons modulate the expression of proteolipid protein in the CNS by Scherer, S S, Vogelbacker, H H, Kamholz, J

“…We examined the expression of mRNA encoding proteolipid protein (PLP), the major myelin protein in the CNS, in developing rat cerebrum, and in normal and…”
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Effect of monthly intravenous cyclophosphamide in rapidly deteriorating multiple sclerosis patients resistant to conventional therapy by Khan, Omar A, Zvartau-Hind, Marina, Caon, Christina, Din, Moeen U, Cochran, Mickey, Lisak, Deena, Tselis, Alexandros C, Kamholz, John A, Garbern, James Y, Lisak, Robert P

“…Fourteen consecutive clinically definite relapsing-remitting multiple sclerosis (MS) patients were treated with monthly intravenous cyclophosphamide (CTX) for…”
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