Search Results - "Kameneva, Marina"

Hemorheological Approach to Improve Perfusion of Red Blood Cells with Reduced Deformability Using Drag-Reducing Polymer (In Vitro Study) by Crompton, Dan, Gudla, Shushma, Waters, Jonathan H., Sundd, Prithu, Kameneva, Marina V.

“…Drag-reducing polymers (DRPs) are nontoxic water-soluble blood additives that have been shown to beneficially alter hemodynamics when delivered intravenously…”
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Addition of Drag-Reducing Polymers to Colloid Resuscitation Fluid Enhances Cerebral Microcirculation and Tissue Oxygenation After Traumatic Brain Injury Complicated by Hemorrhagic Shock by Bragin, Denis E, Bragina, Olga A, Berliba, Lucy, Kameneva, Marina V, Nemoto, Edwin M

“…Hemorrhagic shock (HS) is a severe complication of traumatic brain injury (TBI) that doubles mortality due to severely compromised microvascular cerebral blood…”
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Heart valve scaffold fabrication: Bioinspired control of macro-scale morphology, mechanics and micro-structure by D'Amore, Antonio, Luketich, Samuel K., Raffa, Giuseppe M., Olia, Salim, Menallo, Giorgio, Mazzola, Antonino, D'Accardi, Flavio, Grunberg, Tamir, Gu, Xinzhu, Pilato, Michele, Kameneva, Marina V., Badhwar, Vinay, Wagner, William R.

“…Valvular heart disease is currently treated with mechanical valves, which benefit from longevity, but are burdened by chronic anticoagulation therapy, or with…”
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Rheological effects of drag-reducing polymers improve cerebral blood flow and oxygenation after traumatic brain injury in rats by Bragin, Denis E, Kameneva, Marina V, Bragina, Olga A, Thomson, Susan, Statom, Gloria L, Lara, Devon A, Yang, Yirong, Nemoto, Edwin M

“…Cerebral ischemia has been clearly demonstrated after traumatic brain injury (TBI); however, neuroprotective therapies have not focused on improvement of the…”
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Sex-Specific and Dose-Dependent Effects of Drag-Reducing Polymers on Microcirculation and Tissue Oxygenation in Rats After Traumatic Brain Injury by Bragin, Denis E, Bragina, Olga A, Kameneva, Marina V, Trofimov, Alex O, Nemoto, Edwin M

“…Traumatic brain injury (TBI) ultimately leads to a reduction in the cerebral metabolic rate for oxygen due to ischemia. Previously, we showed that 2 ppm i.v…”
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A Quasi-Mechanistic Mathematical Representation for Blood Viscosity by Hund, Samuel, Kameneva, Marina, Antaki, James

“…Blood viscosity is a crucial element for any computation of flow fields in the vasculature or blood-wetted devices. Although blood is comprised of multiple…”
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Mechanical Blood Trauma in Assisted Circulation: Sublethal RBC Damage Preceding Hemolysis by Olia, Salim E., Maul, Timothy M., Antaki, James F., Kameneva, Marina V.

“…After many decades of improvements in mechanical circulatory assist devices (CADs), blood damage remains a serious problem during support contributing to…”
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Development of a High-Throughput Magnetic Separation Device for Malaria-Infected Erythrocytes by Blue Martin, A., Wu, Wei-Tao, Kameneva, Marina V., Antaki, James F.

“…This study describes a non-dilutive high-gradient magnetic separation (HGMS) device intended to continuously remove malaria-infected red blood cells (iRBCs)…”
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Drag-reducing polymers improve hepatic vaso-occlusion in SCD mice by Crompton, Dan, Vats, Ravi, Pradhan-Sundd, Tirthadipa, Sundd, Prithu, Kameneva, Marina V.

“…•Nanomolar concentrations of drag-reducing polymer (DRP) reduce vaso-occlusion in the liver of sickle cell disease (SCD) mice.•The potential for DRP as a…”
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New insights into the microvascular mechanisms of drag reducing polymers: effect on the cell-free layer by Brands, Judith, Kliner, Dustin, Lipowsky, Herbert H, Kameneva, Marina V, Villanueva, Flordeliza S, Pacella, John J

“…Drag-reducing polymers (DRPs) significantly increase blood flow, tissue perfusion, and tissue oxygenation in various animal models. In rectangular channel…”
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Resuscitation with Drag Reducing Polymers after Traumatic Brain Injury with Hemorrhagic Shock Reduces Microthrombosis and Oxidative Stress by Bragin, Denis E, Bragina, Olga A, Kameneva, Marina V, Nemoto, Edwin M

“…Outcome after traumatic brain injury (TBI) is worsened by hemorrhagic shock (HS); however, the existing volume expansion approach with resuscitation fluids…”
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Improved Cerebral Perfusion Pressure and Microcirculation by Drag Reducing Polymer-Enforced Resuscitation Fluid After Traumatic Brain Injury and Hemorrhagic Shock by Bragin, Denis E, Bragina, Olga A, Trofimov, Alex, Berliba, Lucy, Kameneva, Marina V, Nemoto, Edwin M

“…Hemorrhagic shock (HS) after traumatic brain injury (TBI) reduces cerebral perfusion pressure (CPP) and cerebral blood flow (CBF), increasing hypoxia and…”
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Red Blood Cell Mechanical Fragility Test for Clinical Research Applications by Ziegler, Luke A., Olia, Salim E., Kameneva, Marina V.

“…Red blood cell (RBC) susceptibility to mechanically induced hemolysis, or RBC mechanical fragility (MF), is an important parameter in the characterization of…”
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A Reusable, Compliant, Small Volume Blood Reservoir for In Vitro Hemolysis Testing by Olia, Salim E., Herbertson, Luke H., Malinauskas, Richard A., Kameneva, Marina V.

“…Bench‐top in vitro hemolysis testing is a fundamental tool during the design and regulatory safety evaluation of blood‐contacting medical devices. While…”
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Multilaboratory Study of Flow-Induced Hemolysis Using the FDA Benchmark Nozzle Model by Herbertson, Luke H., Olia, Salim E., Daly, Amanda, Noatch, Christopher P., Smith, William A., Kameneva, Marina V., Malinauskas, Richard A.

“…Multilaboratory in vitro blood damage testing was performed on a simple nozzle model to determine how different flow parameters and blood properties affect…”
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Preclinical performance of a pediatric mechanical circulatory support device: The PediaFlow ventricular assist device by Olia, Salim E., Wearden, Peter D., Maul, Timothy M., Shankarraman, Venkat, Kocyildirim, Ergin, Snyder, Shaun T., Callahan, Patrick M., Kameneva, Marina V., Wagner, William R., Borovetz, Harvey S., Antaki, James F.

“…The PediaFlow (HeartWare International, Inc, Framingham, Mass) is a miniature, implantable, rotodynamic, fully magnetically levitated, continuous-flow…”
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Real time visualization and characterization of platelet deposition under flow onto clinically relevant opaque surfaces by Jamiolkowski, Megan A., Woolley, Joshua R., Kameneva, Marina V., Antaki, James F., Wagner, William R.

“…Although the thrombogenic nature of the surfaces of cardiovascular devices is an important aspect of blood biocompatibility, few studies have examined platelet…”
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Erythrocyte enrichment in hematopoietic progenitor cell cultures based on magnetic susceptibility of the hemoglobin by Jin, Xiaoxia, Abbot, Stewart, Zhang, Xiaokui, Kang, Lin, Voskinarian-Berse, Vanessa, Zhao, Rui, Kameneva, Marina V, Moore, Lee R, Chalmers, Jeffrey J, Zborowski, Maciej

“…Using novel media formulations, it has been demonstrated that human placenta and umbilical cord blood-derived CD34+ cells can be expanded and differentiated…”
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Preclinical biocompatibility assessment of the EVAHEART ventricular assist device: Coating comparison and platelet activation by Snyder, Trevor A., Tsukui, Hiroyuki, Kihara, Shin'Ichiro, Akimoto, Takehide, Litwak, Kenneth N., Kameneva, Marina V., Yamazaki, Kenji, Wagner, William R.

“…Thromboembolism and bleeding remain significant complications of ventricular assist device (VAD) support. Increasing the amount of biocompatibility data…”
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Drag reducing polymers decrease hepatic injury and metastases after liver ischemia-reperfusion by Tohme, Samer, Kameneva, Marina V, Yazdani, Hamza O, Sud, Vikas, Goswami, Julie, Loughran, Patricia, Huang, Hai, Simmons, Richard L, Tsung, Allan

“…Surgery, a crucial therapeutic modality in the treatment of solid tumors, can induce sterile inflammatory processes which can result in metastatic progression…”
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