Search Results - "Kameneva, L. V."
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Low-Dose Ionizing Radiation Affects Mesenchymal Stem Cells via Extracellular Oxidized Cell-Free DNA: A Possible Mediator of Bystander Effect and Adaptive Response
Published in Oxidative medicine and cellular longevity (01-01-2017)“…We have hypothesized that the adaptive response to low doses of ionizing radiation (IR) is mediated by oxidized cell-free DNA (cfDNA) fragments. Here, we…”
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Toxic and DNA damaging effects of a functionalized fullerene in human embryonic lung fibroblasts
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01-07-2016)“…•The influence of a soluble fullerene [C60] derivative (F-828) on HELFs was studied.•At <0.1μM F-828 promotes cell processes of proliferation and…”
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Oxidized Extracellular DNA Suppresses Nitric Oxide Production by Endothelial NO Synthase (eNOS) in Human Endothelial Cells (HUVEC)
Published in Bulletin of experimental biology and medicine (01-06-2014)“…Circulating DNA from patients with cardiovascular diseases reduce the synthesis of NO in endothelial cells, which is probably related to oxidative modifi…”
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Enhanced Expression of iNOS in Human Endothelial Cells during Long-Term Culturing with Extracellular DNA Fragments
Published in Bulletin of experimental biology and medicine (01-08-2010)“…NO synthesis by endothelial cells plays an important role in normal function of the cardiovascular system. This work was designed to evaluate the role of…”
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Fragments of cell-free DNA increase transcription in human mesenchymal stem cells, activate TLR-dependent signal pathway, and suppress apoptosis
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (01-03-2012)“…Human mesenchymal stem cells (MSCs) are widely used in regenerative medicine. However, many questions on the role of different signaling pathways in the…”
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Small doses of radiation activate a signaling pathway aimed at apoptosis inhibition in mesenchymal stem cells
Published in Sechenovskiĭ vestnik (30-09-2019)“…We hypothesize that the anti - apoptotic response in mesenchymal stem cells (MSC) under low doses of radiation may develop through the participation of an…”
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Changes of KEAP1/NRF2 and IKB/NF-κB Expression Levels Induced by Cell-Free DNA in Different Cell Types
Published in Oxidative medicine and cellular longevity (2018)“…Cell-free DNA (cfDNA) is a circulating DNA of nuclear and mitochondrial origin mainly derived from dying cells. Recent studies have shown that cfDNA is a…”
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Cell-free DNA fragments increase transcription in human mesenchymal stem cells, activate TLR-dependent signal pathway and supress apoptosis
Published in Biomeditsinskaia khimiia (01-11-2012)“…Human mesenchymal stem cells (MSCs) are now widely adopted in regenerative medicine. However, many questions on the role of different signaling pathways in the…”
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Bystander effect development in human mesenchymal stem cells after exposure to adaptive dose of X-radiation
Published in Radiat͡s︡ionnai͡a︡ biologii͡a︡, radioėkologii͡a (01-01-2010)“…Transposition and mutual approaching of pericentromeric loci 1q12 of homological chromosomes from the nuclear membrane towards the nuclear centre as well as…”
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The response of human cancer stem cells on low-dose X-ray exposure
Published in Radiat͡s︡ionnai͡a︡ biologii͡a︡, radioėkologii͡a (01-09-2009)“…Recently we found that transposition of homologous chromosomes 1q12 loci towards the nuclear centre and activation of the chromosomal nucleolus-forming regions…”
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