Search Results - "Kamel, Amany O"

Etodolac transdermal cubosomes for the treatment of rheumatoid arthritis: ex vivo permeation and in vivo pharmacokinetic studies by Salah, Salwa, Mahmoud, Azza A., Kamel, Amany O.

“…In this study, transdermal etodolac-loaded cubosomes were developed in order to relieve patient pain and joints stiffness by providing stable etodolac…”
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Functionalized chitosan nanoparticles for cutaneous delivery of a skin whitening agent: an approach to clinically augment the therapeutic efficacy for melasma treatment by Hatem, Shymaa, Elkheshen, Seham A., Kamel, Amany O., Nasr, Maha, Moftah, Noha H., Ragai, Maha H, Elezaby, Reham S., El Hoffy, Nada M.

“…The increase in the production of melanin level inside the skin prompts a patient-inconvenient skin color disorder namely; melasma. This arouses the need to…”
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Stealth lipid polymer hybrid nanoparticles loaded with rutin for effective brain delivery - comparative study with the gold standard (Tween 80): optimization, characterization and biodistribution by Ishak, Rania A. H., Mostafa, Nada M., Kamel, Amany O.

“…The blood-brain barrier is considered the leading physiological obstacle hindering the transport of neurotherapeutics to brain cells. The application of…”
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Enhancement of human oral bioavailability and in vitro antitumor activity of rosuvastatin via spray dried self-nanoemulsifying drug delivery system by Kamel, Amany O, Mahmoud, Azza A

“…The purpose of this study was to develop spray dried self-nanoemulsifying drug delivery system (SNEDDS) tablets of rosuvastatin using mannitol as a carrier…”
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Anticancer effect of atorvastatin nanostructured polymeric micelles based on stearyl-grafted chitosan by Mekhail, George M., Kamel, Amany O., Awad, Gehanne A.S., Mortada, Nahed D.

“…The purpose of this study was to develop a new therapeutic approach for atorvastatin (ATV) adopting nanostructured polymeric micelles for its controlled…”
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Nanosized particulate systems for dermal and transdermal delivery by Hassan, Amany O Kamel, Elshafeey, Ahmed H

“…Nanosized particles have received much attention in industry, biology, and medicine. Today nanotechnology is finding growing applications in pharmaceutical…”
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Gamma sterilization and in vivo evaluation of cationic nanostructured lipid carriers as potential ocular delivery systems for antiglaucoma drugs by Youshia, John, Kamel, Amany O., El Shamy, Abdelhameed, Mansour, Samar

“…Solid lipid nanoparticles and nanostructured lipid carriers showed promising results for enhancement of ocular bioavailability of drugs with poor corneal…”
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Effect of surface charge on the brain delivery of nanostructured lipid carriers in situ gels via the nasal route by Gabal, Yasmine M., Kamel, Amany O., Sammour, Omaima A., Elshafeey, Ahmed H.

“…[Display omitted] The aim of this study was to investigate the influence of the nanocarrier surface charge on brain delivery of a model hydrophilic drug via…”
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An in vitro and in vivo comparative study of directly compressed solid dispersions and freeze dried sildenafil citrate sublingual tablets for management of pulmonary arterial hypertension by Zayed, Reham, Kamel, Amany O., Shukr, Marwa, El-Shamy, Abd El-Hamid

“…Sildenafilcitrate (SILD) orodispersable sublingual tablets (ODSTs) have been developed using two comparative techniques for improving their oral…”
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Interactions between DNA and Gemini surfactant: impact on gene therapy: part I by Ahmed, Taksim, Kamel, Amany O, Wettig, Shawn D

“…Nonviral gene therapy using gemini surfactants is a unique approach to medicine that can be adapted toward the treatment of various diseases. Recently, gemini…”
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Novel green-based polyglycerol polymeric nanoparticles loaded with ferulic acid: A promising approach for hepatoprotection by Mahmoud, Mariam H., El-Gogary, Riham I., Soliman, Mahmoud E., Kamel, Amany O.

“…In the pursuit of eco-friendly and sustainable materials, polyglycerol diacid polymers hold immense promise for drug delivery compared to those derived from…”
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Injectable long acting chitosan/tripolyphosphate microspheres for the intra-articular delivery of lornoxicam: Optimization and in vivo evaluation by Abd-Allah, Hend, Kamel, Amany O., Sammour, Omaima A.

“…•Lornoxicam loaded chitosan/TPP microspheres prepared with ionotropic gelation for intra-articular delivery.•Formulation variables were optimized using full…”
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Ethyl lauroyl arginate-based hydrophobic ion pair complex in lipid nanocapsules: A novel oral delivery approach of rosmarinic acid for enhanced permeability and bioavailability by Gad, Heba A., Ishak, Rania A.H., Labib, Rola M., Kamel, Amany O.

“…[Display omitted] Limited oral bioavailability due to high hydrophilicity restricts the beneficial use of Rosmaranic acid (RM) that is characterized by many…”
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Nano-vesicular systems for melanocytes targeting and melasma treatment: In-vitro characterization, ex-vivo skin retention, and preliminary clinical appraisal by Hatem, Shymaa, Kamel, Amany O., Elkheshen, Seham A., Nasr, Maha, Moftah, Noha H., Ragai, Maha H., El Hoffy, Nada M., Elezaby, Reham S.

“…[Display omitted] •Vesicular systems have the ability to transfer α-arbutin to various skin layers and to act as depots.•α-arbutin nanovesicles containing…”
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Polyethylene Glycol Conjugated Polymeric Nanocapsules for Targeted Delivery of Quercetin to Folate-Expressing Cancer Cells in Vitro and in Vivo by El-Gogary, Riham I, Rubio, Noelia, Wang, Julie Tzu-Wen, Al-Jamal, Wafa’ T, Bourgognon, Maxime, Kafa, Houmam, Naeem, Muniba, Klippstein, Rebecca, Abbate, Vincenzo, Leroux, Frédéric, Bals, Sara, Van Tendeloo, Gustaaf, Kamel, Amany O, Awad, Gehanne A. S, Mortada, Nahed D, Al-Jamal, Khuloud T

“…In this work we describe the formulation and characterization of chemically modified polymeric nanocapsules incorporating the anticancer drug, quercetin, for…”
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Terbinafine hydrochloride nanovesicular gel: In vitro characterization, ex vivo permeation and clinical investigation by AbdelSamie, Sara M., Kamel, Amany O., Sammour, Omaima A., Ibrahim, Shady M.

“…In this work, nanovesicular chitosan gels were prepared for dermal delivery of terbinafine hydrochloride (TBN HCl). Ethosomes and vesicles containing different…”
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Interactions between DNA and gemini surfactant: impact on gene therapy: part II by Ahmed, Taksim, Kamel, Amany O, Wettig, Shawn D

“…Nonviral gene delivery, provides distinct treatment modalities for the inherited and acquired diseases, relies upon the encapsulation of a gene of interest,…”
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A natural protein based platform for the delivery of Temozolomide acid to glioma cells by Helal, Dina O., Rouatbi, Nadia, Han, Shunping, Tzu-Wen Wang, Julie, Walters, Adam A., Abdel-Mottaleb, Mona M.A., Kamel, Amany O., Geneidi, Ahmed-Shawky, Awad, Gehanne A.S., Al-Jamal, Khuloud T.

“…Proposed hypothesis in this study. Brain tumours overexpress SPARC protein which is responsible for the uptake of albumin nanoparticles (HSA NPs). Temozolomide…”
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The interplay of solvent–drug–protein interactions during albumin nanoparticles formulations for temozolomide delivery to brain cancer cells by Helal, Dina O, Abdel-Mottaleb, Mona M A, Kamel, Amany O, Rouatbi, Nadia, Han, Shunping, Geneidi, Ahmed-Shawky, Al-Jamal, Khuloud T, Awad, Gehanne A S

“…Abstract Objectives Temozolomide (TMZ), the first line for glioma therapy, suffers from stability at physiological pH. TMZ was selected as a challenging model…”
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Phospholipid based colloidal poloxamer–nanocubic vesicles for brain targeting via the nasal route by Salama, Hamed A., Mahmoud, Azza A., Kamel, Amany O., Abdel Hady, Mayssa, Awad, Gehanne A.S.

“…[Display omitted] ► New phospholipid based nanocubic vesicular systems were developed. ► The polymeric non-ionic surfactant, poloxamer was incorporated in its…”
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