Search Results - "Kamekura, Ryuta"

Aberrant populations of circulating T follicular helper cells and regulatory B cells underlying idiopathic pulmonary fibrosis by Asai, Yuichiro, Chiba, Hirofumi, Nishikiori, Hirotaka, Kamekura, Ryuta, Yabe, Hayato, Kondo, Shun, Miyajima, Satsuki, Shigehara, Katsunori, Ichimiya, Shingo, Takahashi, Hiroki

“…T follicular helper (Tfh) cells have been identified as a new category of helper T cells, which express CXCR5 on their surface and induce the production of…”
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Cutting Edge: A Critical Role of Lesional T Follicular Helper Cells in the Pathogenesis of IgG4-Related Disease by Kamekura, Ryuta, Takano, Kenichi, Yamamoto, Motohisa, Kawata, Koji, Shigehara, Katsunori, Jitsukawa, Sumito, Nagaya, Tomonori, Ito, Fumie, Sato, Akinori, Ogasawara, Noriko, Tsubomatsu, Chieko, Takahashi, Hiroki, Nakase, Hiroshi, Himi, Tetsuo, Ichimiya, Shingo

“…IgG4-related disease (IgG4-RD) is a newly recognized systemic chronic fibroinflammatory disease. However, the pathogenesis of IgG4-RD remains unknown. To…”
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Activated circulating T follicular helper cells and skewing of T follicular helper 2 cells are down-regulated by treatment including an inhaled corticosteroid in patients with allergic asthma by Miyajima, Satsuki, Shigehara, Katsunori, Kamekura, Ryuta, Takaki, Hiromi, Yabe, Hayato, Ikegami, Ippei, Asai, Yuichiro, Nishikiori, Hirotaka, Chiba, Hirohumi, Uno, Eiji, Takahashi, Hiroki, Ichimiya, Shingo

“…CXCR5+ T follicular helper (TFH) cells primarily promote B cells to produce an antigen-specific antibody through germinal centers (GCs). TFH cells exist in…”
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Functional Interplay between IL-9 and Peptide YY Contributes to Chronic Skin Inflammation by Kamiya, Shiori, Ikegami, Ippei, Yanagi, Masahiro, Takaki, Hiromi, Kamekura, Ryuta, Sato, Taiki, Kobayashi, Keiju, Kamiya, Takafumi, Kamada, Yuka, Abe, Takaya, Inoue, Ken-ichi, Hida, Tokimasa, Uhara, Hisashi, Ichimiya, Shingo

“…Complex interactions between keratinocytes and various cell types, such as inflammatory cells and stromal cells, contribute to the pathogenesis of chronic…”
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Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier by Kamekura, Ryuta, Nava, Porfirio, Feng, Mingli, Quiros, Miguel, Nishio, Hikaru, Weber, Dominique A, Parkos, Charles A, Nusrat, Asma

“…Desmosomal cadherins mediate intercellular adhesion and control epithelial homeostasis. Recent studies show that proteinases play an important role in the…”
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IgG4-related disease administered dupilumab: case series and review of the literature by Kanda, Masatoshi, Kamekura, Ryuta, Sugawara, Masanari, Nagahata, Ken, Suzuki, Chisako, Takano, Kenichi, Takahashi, Hiroki

“…Dupilumab (DUP) is a monoclonal antibody that acts on the interleukin (IL)-4 receptor alpha, which inhibits IL-4 and IL-13 signalling and is approved for type…”
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Circulating T follicular helper 2 cells, T follicular regulatory cells and regulatory B cells are effective biomarkers for predicting the response to house dust mite sublingual immunotherapy in patients with allergic respiratory diseases by Shigehara, Katsunori, Kamekura, Ryuta, Ikegami, Ippei, Sakamoto, Hiroshi, Yanagi, Masahiro, Kamiya, Shiori, Kodama, Kentaro, Asai, Yuichiro, Miyajima, Satsuki, Nishikiori, Hirotaka, Uno, Eiji, Yamamoto, Keisuke, Takano, Kenichi, Chiba, Hirofumi, Ohnishi, Hirofumi, Ichimiya, Shingo

“…The relationships between T follicular helper (Tfh) cells and antigen-specific immunoglobulins (sIgs) in patients with allergic respiratory diseases who are…”
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Novel Mechanisms of Compromised Lymphatic Endothelial Cell Homeostasis in Obesity: The Role of Leptin in Lymphatic Endothelial Cell Tube Formation and Proliferation by Sato, Akinori, Kamekura, Ryuta, Kawata, Koji, Kawada, Masaya, Jitsukawa, Sumito, Yamashita, Keiji, Sato, Noriyuki, Himi, Tetsuo, Ichimiya, Shingo

“…Leptin is a hormone produced by adipose tissue that regulates various physiological processes. Recent studies have shown that the level of circulating leptin…”
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Cytotoxic Tph-like cells are involved in persistent tissue damage in IgG4-related disease by Yabe, Hayato, Kamekura, Ryuta, Yamamoto, Motohisa, Murayama, Kosuke, Kamiya, Shiori, Ikegami, Ippei, Shigehara, Katsunori, Takaki, Hiromi, Chiba, Hirofumi, Takahashi, Hiroki, Takano, Kenichi, Takahashi, Hiroki, Ichimiya, Shingo

“…The aim of this study was to determine pathological features of T peripheral helper (Tph)-like (PD-1 + CXCR5 − CD4 + T) cells in IgG4-related disease…”
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Interleukin 9 mediates T follicular helper cell activation to promote antibody responses by Sato, Taiki, Ikegami, Ippei, Yanagi, Masahiro, Ohyu, Takeshi, Sugaya, Taiki, Shirato, Shotaro, Tanemoto, Masanobu, Kamiya, Shiori, Kikuchi, Kohei, Kamada, Yuka, Nakata, Takehito, Kamekura, Ryuta, Sato, Akinori, Takano, Ken-Ichi, Miyajima, Masahiro, Watanabe, Atsushi, Ichimiya, Shingo

“…Antigen-specific humoral responses are orchestrated through complex interactions among immune cells in lymphoid tissues, including the collaboration between B…”
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Analysis of allergic reaction in IgG4-related disease by Yamamoto, Motohisa, Takano, Ken-ichi, Kamekura, Ryuta, Aochi, Satsuki, Suzuki, Chisako, Ichimiya, Shingo, Takahashi, Hiroki

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Stage classification of IgG4-related dacryoadenitis and sialadenitis by the serum cytokine environment by Yamamoto, Motohisa, Takano, Kenichi, Kamekura, Ryuta, Suzuki, Chisako, Ichimiya, Shingo, Himi, Tetsuo, Nakase, Hiroshi, Takahashi, Hiroki

“…Objectives: Patients with immunoglobulin-G4 related disease (IgG4-RD) diagnosed according to the comprehensive diagnostic criteria (CDC) show varied…”
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CD4+CD8+ T follicular helper cells regulate humoral immunity in chronic inflammatory lesions by Murayama, Kosuke, Ikegami, Ippei, Kamekura, Ryuta, Sakamoto, Hiroshi, Yanagi, Masahiro, Kamiya, Shiori, Sato, Taiki, Sato, Akinori, Shigehara, Katsunori, Yamamoto, Motohisa, Takahashi, Hiroki, Takano, Ken-ichi, Ichimiya, Shingo

“…T follicular helper (Tfh) cells drive humoral immunity by facilitating B cell responses at the initial and recall phases. Recent studies have indicated the…”
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Abnormal [18F]fluorodeoxyglucose accumulation to tori tubarius in IgG4-related disease by Nagahata, Ken, Kanda, Masatoshi, Kamekura, Ryuta, Sugawara, Masanari, Yama, Naoya, Suzuki, Chisako, Takano, Kenichi, Hatakenaka, Masamitsu, Takahashi, Hiroki

“…Objectives Tubarial glands (TGs) are recently refocused gland tissues localized near the tori tubarius in the nasopharynx and their clinical relevance is not…”
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Regulation of Tight Junctions in Upper Airway Epithelium by Masaki, Tomoyuki, Fuchimoto, Jun, Obata, Kazufumi, Nomura, Kazuaki, Keira, Takashi, Miyata, Ryou, Fujii, Nobuhiro, Tsutsumi, Hiroyuki, Himi, Tetsuo, Sawada, Norimasa, Ogasawara, Noriko, Kamekura, Ryuta, Koizumi, Jun-ichi, Ohkuni, Tsuyoshi, Kurose, Makoto, Takano, Ken-ichi, Go, Mitsuru, Kojima, Takashi, Hirakawa, Satoshi

“…The mucosal barrier of the upper respiratory tract including the nasal cavity, which is the first site of exposure to inhaled antigens, plays an important role…”
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Interleukin 5-producing ST2+ memory Th2 cells in IgG4-related dacryoadenitis and sialadenitis by Yamamoto, Motohisa, Takano, Ken-ichi, Kamekura, Ryuta, Aochi, Satsuki, Suzuki, Chisako, Ichimiya, Shingo, Nakase, Hiroshi, Himi, Tetsuo, Takahashi, Hiroki

“…Objectives: Immunoglobulin (Ig) G4-related disease (IgG4-RD) is often complicated by allergic disorders. This study was conducted to investigate the mechanism…”
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The differential diagnosis of IgG4-related disease based on machine learning by Yamamoto, Motohisa, Nojima, Masanori, Kamekura, Ryuta, Kuribara-Souta, Akiko, Uehara, Masaaki, Yamazaki, Hiroki, Yoshikawa, Noritada, Aochi, Satsuki, Mizushima, Ichiro, Watanabe, Takayuki, Nishiwaki, Aya, Komai, Toshihiko, Shoda, Hirofumi, Kitagori, Koji, Yoshifuji, Hajime, Hamano, Hideaki, Kawano, Mitsuhiro, Takano, Ken-Ichi, Fujio, Keishi, Tanaka, Hirotoshi

“…To eliminate the disparity and maldistribution of physicians and medical specialty services, the development of diagnostic support for rare diseases using…”
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Loss of sorting nexin 5 stabilizes internalized growth factor receptors to promote thyroid cancer progression by Jitsukawa, Sumito, Kamekura, Ryuta, Kawata, Koji, Ito, Fumie, Sato, Akinori, Matsumiya, Hiroshi, Nagaya, Tomonori, Yamashita, Keiji, Kubo, Terufumi, Kikuchi, Tomoki, Sato, Noriyuki, Hasegawa, Tadashi, Kiyonari, Hiroshi, Mukumoto, Yoshiko, Takano, Ken‐ichi, Himi, Tetsuo, Ichimiya, Shingo

“…Thyroid carcinoma is the most common endocrine malignancy and its prevalence has recently been increasing worldwide. We previously reported that the level of…”
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Clinical utility of 18F‐fluorodeoxyglucose/positron emission tomography in diagnosis of immunoglobulin G4–related sclerosing sialadenitis by Takano, Kenichi, Yajima, Ryoto, Kamekura, Ryuta, Yamamoto, Motohisa, Takahashi, Hiroki, Yama, Naoya, Hatakenaka, Masamitsu, Himi, Tetsuo

“…Objectives/Hypothesis The aim of this study was to evaluate the utility of 18F‐fluorodeoxyglucose (FDG) positron emission tomography/computed tomography…”
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Potential utility of core needle biopsy in the diagnosis of IgG4-related dacryoadenitis and sialadenitis by Takano, Kenichi, Okuni, Tsuyoshi, Yamamoto, Keisuke, Kamekura, Ryuta, Yajima, Ryoto, Yamamoto, Motohisa, Takahashi, Hiroki, Himi, Tetsuo

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