Search Results - "Kamei, Noriyuki"

Discovery of 2‑(Cyclopentylamino)thieno[3,2‑d]pyrimidin-4(3H)‑one Derivatives as a New Series of Potent Phosphodiesterase 7 Inhibitors by Kawai, Kentaro, Endo, Yusuke, Asano, Takeshi, Amano, Seiji, Sawada, Keisuke, Ueo, Noriko, Takahashi, Nobuaki, Sonoda, Yo, Nagai, Mika, Kamei, Noriyuki, Nagata, Naoya

“…The discovery of a new series of potent phosphodiesterase 7 (PDE7) inhibitors is described. Novel thieno­[3,2-d]­pyrimidin-4­(3H)-one hit compounds were…”
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Cytotoxicity and actin-depolymerizing activity of aplyronine A, a potent antitumor macrolide of marine origin, and its analogs by Kigoshi, Hideo, Suenaga, Kiyotake, Takagi, Masaki, Akao, Atsushi, Kanematsu, Kengo, Kamei, Noriyuki, Okugawa, Youko, Yamada, Kiyoyuki

“…Artificial analogs of aplyronine A ( 1 ), a potent antitumor macrolide, were synthesized and structure–activity (cytotoxicity and actin-depolymerizing…”
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Total Synthesis of (−)-Histrionicotoxin by Adachi, Yohei, Kamei, Noriyuki, Yokoshima, Satoshi, Fukuyama, Tohru

“…A total synthesis of (−)-histrionicotoxin was achieved. Our synthesis features preparation of a pseudosymmetrical dienyne through chirality transfer from an…”
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Cytotoxicity and actin depolymerizing activity of aplyronine A, a potent antitumor macrolide of marine origin, and the natural and artificial analogs by Suenaga, Kiyotake, Kamei, Noriyuki, Okugawa, Youko, Takagi, Masaki, Akao, Atsushi, Kigoshi, Hideo, Yamada, Kiyoyuki

“…The artificial analogs of aplyronine A ( 1), a potent cytotoxic and antitumor macrolide, were synthesized and the structure-activity (cytotoxicity and actin…”
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Correction to Total Synthesis of (−)-Histrionicotoxin by Adachi, Yohei, Kamei, Noriyuki, Yokoshima, Satoshi, Fukuyama, Tohru

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2-(Isopropylamino)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as selective phosphodiesterase 7 inhibitors with potent in vivo efficacy by Endo, Yusuke, Kawai, Kentaro, Asano, Takeshi, Amano, Seiji, Asanuma, Yoshihito, Sawada, Keisuke, Onodera, Yuuta, Ueo, Noriko, Takahashi, Nobuaki, Sonoda, Yo, Kamei, Noriyuki, Irie, Tetsumi

“…A new series of thienopyrimidinones is synthesized and evaluated as selective phosphodiesterase 7 (PDE7) inhibitors for the treatment of inflammatory diseases…”
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Discovery and SAR study of 2-(4-pyridylamino)thieno[3,2-d]pyrimidin-4(3H)-ones as soluble and highly potent PDE7 inhibitors by Endo, Yusuke, Kawai, Kentaro, Asano, Takeshi, Amano, Seiji, Asanuma, Yoshihito, Sawada, Keisuke, Ogura, Keiji, Nagata, Naoya, Ueo, Noriko, Takahashi, Nobuaki, Sonoda, Yo, Kamei, Noriyuki

“…[Display omitted] The discovery and SAR study of a new series of soluble and highly potent phosphodiesterase (PDE) 7 inhibitors are described herein. We…”
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Reverse hydroxamate-based selective TACE inhibitors by Kamei, Noriyuki, Tanaka, Tomohiro, Kawai, Kentaro, Miyawaki, Kyosei, Okuyama, Akihiko, Murakami, Yoshiko, Arakawa, Yoshio, Haino, Makoto, Harada, Tatsuhiro, Shimano, Masanao

“…Reverse hydroxamate-based selective TACE inhibitors are described. Compound 18 has a potent TACE inhibitory activity and a high selectivity against MMPs, and…”
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Enantioselective total synthesis of the antifungal dilactone, UK-2A: The determination of the relative and absolute configurations by Shimano, Masanao, Shibata, Tetsuo, Kamei, Noriyuki

“…The synthesis of the antifungal dilactone, UK-2A, is described. In addition to providing a workable synthetic route to this potent antifungal antibiotic, this…”
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Total synthesis of the antifungal dilactones UK-2A and UK-3A: The determination of their relative and absolute configurations, analog synthesis and antifungal activities by Shimano, Masanao, Kamei, Noriyuki, Shibata, Tetsuo, Inoguchi, Kiyoshi, Itoh, Nobuko, Ikari, Takashi, Senda, Hisato

“…The synthesis of the antifungal dilactones, UK-2A and UK-3A, is described. In addition to providing a workable synthetic route to these potent antifungal…”
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