Search Results - "Kamei, Daniel T."

The intracellular trafficking pathway of transferrin by Mayle, Kristine M., Le, Alexander M., Kamei, Daniel T.

“…Transferrin (Tf) is an iron-binding protein that facilitates iron-uptake in cells. Iron-loaded Tf first binds to the Tf receptor (TfR) and enters the cell…”
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Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions by Mishra, Abhijit, Lai, Ghee Hwee, Schmidt, Nathan W, Sun, Victor Z, Rodriguez, April R, Tong, Rong, Tang, Li, Cheng, Jianjun, Deming, Timothy J, Kamei, Daniel T, Wong, Gerard C. L

“…Cell-penetrating peptides (CPPs), such as the HIV TAT peptide, are able to translocate across cellular membranes efficiently. A number of mechanisms, from…”
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Incorporation of multicellular spheroids into 3‐D polymeric scaffolds provides an improved tumor model for screening anticancer drugs by Ho, Won Jin, Pham, Edward A., Kim, Jun W., Ng, Christopher W., Kim, Jae H., Kamei, Daniel T., Wu, Benjamin M.

“…Development of cancer therapeutics requires a thorough evaluation of drug efficacy in vitro before animal testing and subsequent clinical trials…”
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Single-step, paper-based concentration and detection of a malaria biomarker by Pereira, David Y., Chiu, Ricky Y.T., Zhang, Samantha C.L., Wu, Benjamin M., Kamei, Daniel T.

“…[Display omitted] •Micellar two-phase systems rapidly separated and formed within fiberglass paper.•Two-phase systems concentrated biomarkers for use in the…”
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Dual Chemotherapeutic Loading in Oxalate Transferrin-Conjugated Polymersomes Incorporated into Chitosan Hydrogels for Site-Specific Targeting of Melanoma Cells by Aranha, Mariana de C, Alencar, Luciana M R, Souto, Eliana B, Kamei, Daniel T, Lopes, André M

“…In this work, we developed a smart drug delivery system composed of poly (ethylene glycol)- -poly (ε-caprolactone) (PEG-PCL)-based polymersomes (Ps) loaded…”
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Transferrin receptors and glioblastoma multiforme: Current findings and potential for treatment by Voth, Brittany, Nagasawa, Daniel T, Pelargos, Panayiotis E, Chung, Lawrance K, Ung, Nolan, Gopen, Quinton, Tenn, Stephen, Kamei, Daniel T, Yang, Isaac

“…Abstract The current standard treatment for glioblastoma multiforme (GBM) is surgery followed by chemotherapy and external radiation. Even with the standard…”
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Enhancing the lateral-flow immunoassay for detection of proteins using an aqueous two-phase micellar system by Mashayekhi, Foad, Le, Alexander M., Nafisi, Parsa M., Wu, Benjamin M., Kamei, Daniel T.

“…The lateral-flow (immuno)assay (LFA) has been widely investigated for the detection of molecular, macromolecular, and particle targets at the point-of-need due…”
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An Aqueous Two-Phase System for the Concentration and Extraction of Proteins from the Interface for Detection Using the Lateral-Flow Immunoassay by Chiu, Ricky Y T, Thach, Alison V, Wu, Chloe M, Wu, Benjamin M, Kamei, Daniel T

“…The paper-based immunoassay for point-of-care diagnostics is widely used due to its low cost and portability over traditional lab-based assays. Lateral-flow…”
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Ionic Liquid Aqueous Two-Phase Systems for the Enhanced Paper-Based Detection of Transferrin and Escherichia coli by Yee, Matthew F, Emmel, Grace N, Yang, Eric J, Lee, Eumene, Paek, Justin H, Wu, Benjamin M, Kamei, Daniel T

“…Aqueous two-phase systems (ATPSs) have been widely utilized for liquid-liquid extraction and purification of biomolecules, with some studies also demonstrating…”
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Developments in integrating nucleic acid isothermal amplification and detection systems for point-of-care diagnostics by Pumford, Elizabeth A., Lu, Jiakun, Spaczai, Iza, Prasetyo, Matthew E., Zheng, Elaine M., Zhang, Hanxu, Kamei, Daniel T.

“…Early disease detection through point-of-care (POC) testing is vital for quickly treating patients and preventing the spread of harmful pathogens. Disease…”
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Reinventing Cell Penetrating Peptides Using Glycosylated Methionine Sulfonium Ion Sequences by Kramer, Jessica R, Schmidt, Nathan W, Mayle, Kristine M, Kamei, Daniel T, Wong, Gerard C. L, Deming, Timothy J

“…Cell penetrating peptides (CPPs) are intriguing molecules that have received much attention, both in terms of mechanistic analysis and as transporters for…”
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Intracellular Trafficking Considerations in the Development of Natural Ligand-Drug Molecular Conjugates for Cancer by Yoon, Dennis J., Liu, Christina T., Quinlan, Devin S., Nafisi, Parsa M., Kamei, Daniel T.

“…Overexpressed receptors, characteristic of many cancers, have been targeted by various researchers to achieve a more specific treatment for cancer. A common…”
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Investigating bottom phase extraction from aqueous two-phase systems for detecting bacteria using the lateral-flow immunoassay by Luu, Audrey P., Rao, Shreedevi S., Malik, Humza Y., Shi, Robin B., Toubian, Adam A., Kamei, Daniel T.

“…Lateral-flow immunoassays (LFAs) can be used to diagnose urinary tract infections caused by Escherichia coli (E. coli) at the point of care. Unfortunately,…”
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Polyarginine segments in block copolypeptides drive both vesicular assembly and intracellular delivery by Deming, Timothy J, Holowka, Eric P, Sun, Victor Z, Kamei, Daniel T

“…Polymeric vesicles are a relatively new class of nanoscale self-assembled materials that show great promise as robust encapsulants. Compared with liposomes,…”
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Automation of Biomarker Preconcentration, Capture, and Nanozyme Signal Enhancement on Paper-Based Devices by Bradbury, Daniel W, Azimi, Milad, Diaz, Alexia J, Pan, April A, Falktoft, Cecilie H, Wu, Benjamin M, Kamei, Daniel T

“…Infectious diseases remain one of the leading causes of deaths in developing countries because of a lack of basic sanitation, healthcare clinics, and…”
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Inhibition of transferrin iron release increases in vitro drug carrier efficacy by Lao, Bert J., Tsai, Wen-Lin P., Mashayekhi, Foad, Pham, Edward A., Mason, Anne B., Kamei, Daniel T.

“…Transferrin (Tf) conjugates of CRM107 are currently being tested in clinical trials for treatment of malignant gliomas. However, the rapid cellular recycling…”
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On-demand nanozyme signal enhancement at the push of a button for the improved detection of SARS-CoV-2 nucleocapsid protein in serum by Bradbury, Daniel W, Trinh, Jasmine T, Ryan, Milo J, Cantu, Cassandra M, Lu, Jiakun, Nicklen, Frances D, Du, Yushen, Sun, Ren, Wu, Benjamin M, Kamei, Daniel T

“…We developed an innovative 3D printed casing that incorporates a lateral-flow immunoassay, dehydrated signal enhancement reagents, and a sealed buffer chamber…”
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Development of a Universal Lateral-Flow Immunoassay Interpretation Device Prototype with Quantitative Output for Blind or Visually Impaired Individuals by Guillermo, Noah A., Chawla, Rohan, Zheng, Elaine M., Battikha, Adel A., Chen, Kyle J., Kamei, Daniel T.

“…The lateral-flow immunoassay (LFA) has proven to be an effective point-of-care diagnostic for the rapid detection of target analytes in patient samples…”
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Application of the aqueous two-phase system and nanozyme signal enhancement for the improved detection of Plasmodium lactate dehydrogenase in serum by Nicklen, Frances D., Diaz, Alexia J., Lu, Jiakun, Patel, Salil T., Zheng, Elaine M., Campbell, Veronica R., Wu, Benjamin M., Kamei, Daniel T.

“…Malaria is an infectious disease that can cause severe sickness and death if not diagnosed and treated in a timely manner. The current gold standard technique…”
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A one-pot, isothermal DNA sample preparation and amplification platform utilizing aqueous two-phase systems by Cheung, Sherine F., Yee, Matthew F., Le, Nguyen K., Wu, Benjamin M., Kamei, Daniel T.

“…Infectious diseases remain one of the major causes of death worldwide in developing countries. While screening via conventional polymerase chain reaction (PCR)…”
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