Search Results - "Kambey, Piniel Alphayo"

Vitamin C Alleviates the Negative Effects of Heat Stress on Reproductive Processes by Regulating Amino Acid Metabolism in Granulosa Cells by Sammad, Abdul, Ahmed, Tanveer, Ullah, Khair, Hu, Lirong, Luo, Hanpeng, Alphayo Kambey, Piniel, Faisal, Shah, Zhu, Huabin, Li, Yinxiong, Wang, Yachun

“…Heat stress-induced biochemical alterations in ovarian follicles compromise the function of granulosa cells (GCs) and the developmental competence of oocytes…”
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Distinct serum GDNF coupling with brain structural and functional changes underlies cognitive status in Parkinson's disease by Tang, Chuanxi, Sun, Ruiao, Xue, Ke, Wang, Mengying, Liang, Sijie, Kambey, Piniel Alphayo, Shi, Mingyu, Wu, Changyu, Chen, Gang, Gao, Dianshuai

“…Aim Aberrations in brain connections are implicated in the pathogenesis of Parkinson's disease (PD). We previously demonstrated that Glial cell‐derived…”
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Susceptibility of cytoskeletal-associated proteins for tumor progression by Ayanlaja, Abiola Abdulrahman, Hong, Xiaoliang, Cheng, Bo, Zhou, Han, Kanwore, Kouminin, Alphayo-Kambey, Piniel, Zhang, Lin, Tang, Chuanxi, Adeyanju, Muinat Moronke, Gao, Dianshuai

“…The traditional functions of cytoskeletal-associated proteins (CAPs) in line with polymerization and stabilization of the cytoskeleton have evolved and are…”
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Microglial SIX2 suppresses lipopolysaccharide (LPS)-induced neuroinflammation by up-regulating FXYD2 expression by Cao, Xia-yin, Liu, Yi, Kan, Jia-shuo, Huang, Xin-xing, Kambey, Piniel Alphayo, Zhang, Can-tang, Gao, Jin

“…Parkinson’s disease (PD) is a severe neurodegenerative disease associated with the loss of dopaminergic (DA) neurons in the substantia nigra (SN). Although its…”
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Cancer Metabolism: The Role of Immune Cells Epigenetic Alteration in Tumorigenesis, Progression, and Metastasis of Glioma by Kanwore, Kouminin, Kanwore, Konimpo, Adzika, Gabriel Komla, Abiola, Ayanlaja Abdulrahman, Guo, Xiaoxiao, Kambey, Piniel Alphayo, Xia, Ying, Gao, Dianshuai

“…Glioma is a type of brain and spinal cord tumor that begins in glial cells that support the nervous system neurons functions. Age, radiation exposure, and…”
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HIV-1 gp120 Protein Activates Cyclin-Dependent Kinase 1, a Possible Link to Central Nervous System Cell Death by Saro, Adonira, Gao, Zhaolin, Kambey, Piniel Alphayo, Li, Min, Huang, Jufang

“…Human immunodeficiency virus-1 (HIV-1)-associated neurodegenerative disorder (HAND) is frequently reported in HIV-infected individuals. The gp120 envelope…”
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SOX1 Is a Backup Gene for Brain Neurons and Glioma Stem Cell Protection and Proliferation by Kanwore, Kouminin, Guo, Xiao-xiao, Abdulrahman, Ayanlaja Abiola, Kambey, Piniel Alphayo, Nadeem, Iqra, Gao, Dianshuai

“…Failed neuroprotection leads to the initiation of several diseases. SOX1 plays many roles in embryogenesis, oncogenesis, and male sex determination, and can…”
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The orphan nuclear receptor Nurr1 agonist amodiaquine mediates neuroprotective effects in 6-OHDA Parkinson’s disease animal model by enhancing the phosphorylation of P38 mitogen-activated kinase but not PI3K/AKT signaling pathway by Kambey, Piniel Alphayo, Chengcheng, Ma, Xiaoxiao, Guo, Abdulrahman, Ayanlaja Abiola, Kanwore, Kouminin, Nadeem, Iqra, Jiao, Wu, Gao, Dianshuai

“…Recent studies implicate the defects or altered expression of the orphan nuclear receptor Nurr1 gene in the substantia nigra in Parkinson’s disease…”
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HIV-Proteins-Associated CNS Neurotoxicity, Their Mediators, and Alternative Treatments by Saro, Adonira, Gao, Zhaolin, Kambey, Piniel Alphayo, Pielnaa, Paul, Marcellin, Dama Faniriantsoa Henrio, Luo, Aixiang, Zheng, Ruping, Huang, Zhongjun, Liao, Lvshuang, Zhao, Mingxuan, Suo, Liangpeng, Lu, Shuang, Li, Min, Cai, Deyang, Chen, Dan, Yu, Haiyang, Huang, Jufang

“…Human immunodeficiency virus (HIV)-infected people's livelihoods are gradually being prolonged with the use of combined antiretroviral therapy (ART)…”
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Failure of Glial Cell-Line Derived Neurotrophic Factor (GDNF) in Clinical Trials Orchestrated By Reduced NR4A2 (NURR1) Transcription Factor in Parkinson's Disease. A Systematic Review by Kambey, Piniel Alphayo, Kanwore, Kouminin, Ayanlaja, Abiola Abdulrahman, Nadeem, Iqra, Du, YinZhen, Buberwa, Wokuheleza, Liu, WenYa, Gao, Dianshuai

“…Parkinson's disease (PD) is one of the most common neurodegenerative maladies with unforeseen complex pathologies. While this neurodegenerative disorder's…”
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Single-nuclei RNA sequencing uncovers heterogenous transcriptional signatures in Parkinson's disease associated with nuclear receptor-related factor 1 defect by Kambey, Piniel, Liu, Wen-Ya, Wu, Jiao, Bosco, Bakwatanisa, Nadeem, Iqra, Kanwore, Kouminin, Gao, Dian-Shuai

“…Previous studies have found that deficiency in nuclear receptor-related factor 1 (Nurr1), which participates in the development, differentiation, survival, and…”
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Lower GDNF Serum Level Is a Possible Risk Factor for Constipation in Patients With Parkinson Disease: A Case-Control Study by Chen, Gang, Du, Yinzhen, Li, Xue, Kambey, Piniel Alphayo, Wang, Li, Xia, Ying, Tang, Chuanxi, Shi, Mingyu, Zai-Li, Li, Zai-E, Xin, Xiao-Ling, Qin, Dian-Shuai, Gao

“…Constipation is a significant symptom of Parkinson's disease (PD). Glial-derived neurotrophic factor (GDNF) is important for the morphogenesis of the enteric…”
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Glutathione S-Transferases S1, Z1 and A1 Serve as Prognostic Factors in Glioblastoma and Promote Drug Resistance through Antioxidant Pathways by Cheng, Bo, Wang, Yu, Ayanlaja, Abiola Abdulrahman, Zhu, Jing, Kambey, Piniel Alphayo, Qiu, Ziqiang, Zhang, Caiyi, Hu, Wei

“…The glutathione S-transferase (GST) family of detoxification enzymes can regulate the malignant progression and drug resistance of various tumors…”
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Correction: Cheng et al. Glutathione S-Transferases S1, Z1 and A1 Serve as Prognostic Factors in Glioblastoma and Promote Drug Resistance through Antioxidant Pathways. Cells 2022, 11 , 3232 by Cheng, Bo, Wang, Yu, Ayanlaja, Abiola Abdulrahman, Zhu, Jing, Kambey, Piniel Alphayo, Qiu, Ziqiang, Zhang, Caiyi, Hu, Wei

“…The authors wish to make the following change to their paper [...]…”
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Doublecortin undergo nucleocytoplasmic transport via the RanGTPase signaling to promote glioma progression by Ayanlaja, Abiola Abdulrahman, Ji, Guanquan, Wang, Jie, Gao, Yue, Cheng, Bo, Kanwore, Kouminin, Zhang, Lin, Xiong, Ye, Kambey, Piniel Alphayo, Gao, Dianshuai

“…Nuclear translocation of several oncogenic proteins have previously been reported, but neither the translocation of doublecortin (DCX) nor the mechanism…”
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Blunt dopamine transmission due to decreased GDNF in the PFC evokes cognitive impairment in Parkinson's disease by Tang, Chuan-Xi, Chen, Jing, Shao, Kai-Quan, Liu, Ye-Hao, Zhou, Xiao-Yu, Ma, Cheng-Cheng, Liu, Meng-Ting, Shi, Ming-Yu, Kambey, Piniel, Wang, Wei, Ayanlaja, Abiola, Liu, Yi-Fang, Xu, Wei, Chen, Gang, Wu, Jiao, Li, Xue, Gao, Dian-Shuai

“…Studies have found that the absence of glial cell line-derived neurotrophic factor may be the primary risk factor for Parkinson's disease. However, there have…”
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Testosterone upregulates glial cell line-derived neurotrophic factor (GDNF) and promotes neuroinflammation to enhance glioma cell survival and proliferation by Kanwore, Kouminin, Kanwore, Konimpo, Guo, Xiaoxiao, Xia, Ying, Zhou, Han, Zhang, Lin, Adzika, Gabriel Komla, Joseph, Adu-Amankwaah, Abiola, Ayanlaja Abdulrahman, Mu, Peipei, Kambey, Piniel Alphayo, Noah, Marie Louis N'dzie, Gao, DianShuai

“…BACKGROUNDTestosterone contributes to male organism development, such as bone density, muscle development, and fat repartition. Estrogen (derived from…”
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Extracellular and Intracellular Factors in Brain Cancer by Kanwore, Kouminin, Kambey, Piniel Alphayo, Guo, Xiao-Xiao, Abiola, Ayanlaja Abdulrahman, Xia, Ying, Gao, Dianshuai

“…The external and internal factors of the cell are critical to glioma initiation. Several factors and molecules have been reported to be implicated in the…”
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The bi-directional association between bipolar disorder and obesity: Evidence from Meta and bioinformatics analysis by Kambey, Piniel Alphayo, Kodzo, Lalit Dzifa, Serojane, Fattimah, Oluwasola, Bolorunduro Janet

“…Background The globally high prevalence of both obesity and bipolar disorder makes the bidirectional relationship between the two disorders a pivotal…”
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Targeting serum response factor (SRF) deactivates ΔFosB and mitigates Levodopa-induced dyskinesia in a mouse model of Parkinson's disease by Kambey, Piniel Alphayo, Wu, Jiao, Liu, WenYa, Su, Mingyu, Buberwa, Wokuheleza, Tang, Chuanxi

“…L-3,4-dihydroxyphenylalanine (L-DOPA) is currently the preferred treatment for Parkinson's Disease (PD) and is considered the gold standard. However, prolonged…”
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