Search Results - "Kamber, Dominique"
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90 Unbiased proteomic profiling leads to the discovery of a novel non-invasive blood-based protein panel with significant positive predictive value in pancreatic and colorectal cancers
Published in Journal for immunotherapy of cancer (01-11-2021)“…BackgroundMass spectrometry-based discovery proteomics has recently emerged as a high-throughput method for the proteomic profiling in biofluid samples from…”
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Biomarker Candidates for Tumors Identified from Deep-Profiled Plasma Stem Predominantly from the Low Abundant Area
Published in Journal of proteome research (01-07-2022)“…The plasma proteome has the potential to enable a holistic analysis of the health state of an individual. However, plasma biomarker discovery is difficult due…”
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Evaluation of endogenous urinary biomarkers for indirect detection of urine adulteration attempts by five different chemical adulterants in mass spectrometry methods
Published in Drug testing and analysis (01-05-2019)“…Reliable detection of urine adulteration attempts to circumvent positive drug testing represents a critical step for laboratories in abstinence control…”
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Abstract 3847: Target identification of a multi-pass transmembrane G protein coupled receptor using limited-proteolysis coupled mass spectrometry (LiP-MS)
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract In drug discovery, target identification (ID) after phenotypic screens is a resource-intensive endeavor aimed to understand compound’s mechanism of…”
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Suitability evaluation of new endogenous biomarkers for the identification of nitrite‐based urine adulteration in mass spectrometry methods
Published in Drug testing and analysis (01-02-2019)“…Urine adulteration to circumvent positive drug testing is a fundamental challenge for toxicological laboratories all over the world. Untargeted mass…”
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Abstract 3920: Precise solid tumor classification through unbiased quantification of proteoforms deep into tissue leakage
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Blood is the most frequently used sample in diagnostic processes, and its liquid component is known as plasma. Plasma potentially contains molecular…”
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Abstract 5776: Target identification, selectivity profiling and binding site mapping of small molecule and peptide drugs by LiP-MS
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Target identification in the cellular context is a critical step for both target-based and phenotypic drug discovery. Limited proteolysis coupled with…”
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