Search Results - "Kambe, Mariko"

Differential roles of gangliosides in malignant properties of melanomas by Ohmi, Yuhsuke, Kambe, Mariko, Ohkawa, Yuki, Hamamura, Kazunori, Tajima, Orie, Takeuchi, Rika, Furukawa, Koichi, Furukawa, Keiko

“…Ganglioside GD3 is widely expressed in human malignant melanomas, and has been reported to be involved in the increased cell proliferation and invasion. In…”
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Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas by Yesmin, Farhana, Furukawa, Keiko, Kambe, Mariko, Ohmi, Yuhsuke, Bhuiyan, Robiul Hasan, Hasnat, Mohammad Abul, Mizutani, Momoka, Tajima, Orie, Hashimoto, Noboru, Tsuchida, Akiko, Kaneko, Kei, Furukawa, Koichi

“…Exosomes (small extracellular vesicles: EVs) have attracted increasing attention from basic scientists and clinicians since they play important roles in…”
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Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins by Yesmin, Farhana, Bhuiyan, Robiul H, Ohmi, Yuhsuke, Yamamoto, Satoko, Kaneko, Kei, Ohkawa, Yuki, Zhang, Pu, Hamamura, Kazunori, Cheung, Nai-Kong V, Kotani, Norihiro, Honke, Koichi, Okajima, Tetsuya, Kambe, Mariko, Tajima, Orie, Furukawa, Keiko, Furukawa, Koichi

“…Gangliosides have been considered to modulate cell signals in the microdomain of the cell membrane, lipid/rafts, or glycolipid-enriched microdomain/rafts…”
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Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains by Ohkawa, Yuki, Miyazaki, Sayaka, Hamamura, Kazunori, Kambe, Mariko, Miyata, Maiko, Tajima, Orie, Ohmi, Yuhsuke, Yamauchi, Yoshio, Furukawa, Koichi, Furukawa, Keiko

“…Ganglioside GD3 is widely expressed in human malignant melanoma cell lines and tumors. Previously, we reported that GD3+ cells show stronger tyrosine…”
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Ganglioside GD3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas by Furukawa, Keiko, Kambe, Mariko, Miyata, Maiko, Ohkawa, Yuki, Tajima, Orie, Furukawa, Koichi

“…Ganglioside GD3 is highly expressed in human melanomas and enhances malignant properties of melanomas, such as cell proliferation and invasion activity. In…”
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Crucial roles of exosomes secreted from ganglioside GD3/GD2-positive glioma cells in enhancement of the malignant phenotypes and signals of GD3/GD2-negative glioma cells by Hasnat, Mohammad Abul, Ohmi, Yuhsuke, Yesmin, Farhana, Kambe, Mariko, Kawamoto, Yoshiyuki, Bhuiyan, Robiul H, Mizutani, Momoka, Hashimoto, Noboru, Tsuchida, Akiko, Ohkawa, Yuki, Kaneko, Kei, Tajima, Orie, Furukawa, Keiko, Furukawa, Koichi

“…Neuroectoderm-derived tumors characteristically express gangliosides such as GD3 and GD2. Many studies have reported that gangliosides GD3/GD2 enhance…”
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Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides by Miyata, Maiko, Kambe, Mariko, Tajima, Orie, Moriya, Setsuko, Sawaki, Hiromichi, Hotta, Hiroshi, Kondo, Yuji, Narimatsu, Hisashi, Miyagi, Taeko, Furukawa, Koichi, Furukawa, Keiko

“…NEU3 is a membrane sialidase specific for gangliosides. Its increased expression and implication in some cancers have been reported. Here, we analyzed NEU3…”
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Phase I study of irinotecan by 24-h intravenous infusion in combination with 5-fluorouracil in metastatic colorectal cancer by Kambe, Mariko, Kikuchi, Hiroaki, Gamo, Makio, Yoshioka, Takashi, Ohashi, Yasuo, Kanamaru, Ryunosuke

“…Background This study was intended to ascertain the feasibility of a combination therapy with irinotecan by 24-h intravenous infusion (24-h CPT-11) and…”
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TNFα-signal and cAMP-mediated signals oppositely regulate melanoma- associated ganglioside GD3 synthase gene in human melanocytes by Takeuchi, Rika, Kambe, Mariko, Miyata, Maiko, Jeyadevan, Upul, Tajima, Orie, Furukawa, Koichi, Furukawa, Keiko

“…Analyses of expression and regulation of ganglioside synthases in melanocytes are important to understand roles of gangliosides in melanomagenesis. In this…”
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Induction of p53‐independent Apoptosis Associated with G2M Arrest Following DNA Damage in Human Colon Cancer Cell Lines by Arita, Daisaku, Kambe, Mariko, Ishioka, Chikashi, Kanamaru, Ryunosuke

“…The tumor suppressor p53 protein induces apoptosis in response to various kinds of DNA damage in normal cells, but it is still unclear whether or not apoptosis…”
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Anti-K-ras ribozyme induces growth inhibition and increased chemosensitivity in human colon cancer cells by Funato, T, Ishii, T, Kambe, M, Scanlon, K J, Sasaki, T

“…Colon cancer is one of the carcinomas that is resistant to a variety of therapies. To develop a new therapy by regulating the activated K-ras gene in colon…”
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Application of ion-trap LC/MS/MS for determination of acrylamide in processed foods by Tsutsumiuchi, K. (Chubu Univ., Kasugai, Aichi (Japan)), Hibino, M, Kambe, M, Oishi, K, Okada, M, Miwa, J, Taniguchi, H

“…Ion-trap LC/MS/MS was evaluated for use in the determination of acrylamide (AA) in processed foods. Multiple reaction monitoring (MRM) analysis of a series of…”
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Functional validation of novel variants in B4GALNT1 associated with early‐onset complex hereditary spastic paraplegia with impaired ganglioside synthesis by Alecu, Julian Emanuel, Ohmi, Yuhsuke, Bhuiyan, Robiul H., Inamori, Kei‐ichiro, Nitta, Takahiro, Saffari, Afshin, Jumo, Hellen, Ziegler, Marvin, Gusmao, Claudio Melo, Sharma, Nutan, Ohno, Shiho, Manabe, Noriyoshi, Yamaguchi, Yoshiki, Kambe, Mariko, Furukawa, Keiko, Sahin, Mustafa, Inokuchi, Jin‐ichi, Furakawa, Koichi, Ebrahimi‐Fakhari, Darius

“…Childhood‐onset forms of hereditary spastic paraplegia are ultra‐rare diseases and often present with complex features. Next‐generation‐sequencing allows for…”
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UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6 by Miyata, Maiko, Ichihara, Masatoshi, Tajima, Orie, Sobue, Sayaka, Kambe, Mariko, Sugiura, Kazumitsu, Furukawa, Koichi, Furukawa, Keiko

“…•Melanocytes showed low ST8SIA1 and high B3GALT4 levels in contrast with melanomas.•Direct UVB irradiation of melanocytes did not induce ganglioside synthase…”
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Randomized Phase II Trial Comparing Carboplatin Plus Weekly Paclitaxel and Docetaxel Alone in Elderly Patients With Advanced Non‐Small Cell Lung Cancer: North Japan Lung Cancer Group Trial 0801 by Maemondo, Makoto, Inoue, Akira, Sugawara, Shunichi, Harada, Toshiyuki, Minegishi, Yuji, Usui, Kazuhiro, Miwa, Koji, Morikawa, Naoto, Kambe, Mariko, Ube, Kenji, Watanabe, Kana, Ishimoto, Osamu, Sakakibara, Tomohiro, Gemma, Akihiko, Nukiwa, Toshihiro

“…Background. Standard first‐line chemotherapy for elderly non‐small cell lung cancer (NSCLC) patients has been monotherapy with vinorelbine or gemcitabine…”
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Ganglioside GD 3 induces convergence and synergism of adhesion and hepatocyte growth factor/Met signals in melanomas by Furukawa, Keiko, Kambe, Mariko, Miyata, Maiko, Ohkawa, Yuki, Tajima, Orie, Furukawa, Koichi

“…Ganglioside GD 3 is highly expressed in human melanomas and enhances malignant properties of melanomas, such as cell proliferation and invasion activity. In…”
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Identification of cardiac progenitors that survive in the ischemic human heart after ventricular myocyte death by Omatsu-Kanbe, Mariko, Nozuchi, Nozomi, Nishino, Yuka, Mukaisho, Ken-ichi, Sugihara, Hiroyuki, Matsuura, Hiroshi

“…Atypically-shaped cardiomyocytes (ACMs) are beating heart cells identified in the cultures of cardiomyocyte-removed fractions obtained from adult mouse hearts…”
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Phase II trial of cetuximab (Cmab) plus irinotecan (CPT-11) for chemorefractory Japanese patients with advanced and/or metastatic colorectal cancer (mCRC), to evaluate the efficacy and safety based on KRAS , BRAF , PIK3CA , NRAS , and AKT1 mutation status (T-CORE0801) by Shimodaira, Hideki, Soeda, Hiroshi, Ohori, Hisatsugu, Akiyama, Shoko, Kambe, Mariko, Murakawa, Yasuko, Suzuki, Takao, Kato, Satoshi, Itoh, Jugoh, Watanabe, Mika, Yamaguchi, Takuhiro, Kato, Shunsuke, Ishioka, Chikashi

“…Abstract only e14597 Background: Mutations in the KRAS gene have been identified as negative predictors of response to anti-epidermal growth factor receptor…”
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Enhancement of the efficacy of anticancer drugs with electroporation: Successful electrochemotherapy against gastric cancer cell lines in vivo and in vitro by Kambe, Mariko, Arita, Daisaku, Kikuchi, Hiroaki, Funato, Tadao, Tezuka, Fumiaki, Gamo, Makio, Murakawa, Yasuko, Kanamaru, Ryunosuke

“…The purpose of this study was to determine whether micropore formation caused by application of an electric current can increase the influx of anticancer drugs…”
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Unrestricted T Cell-Mediated Cytotoxicity to Major Histocompatibility Antigen Generated with Tumor Hybrid Cells by KAMBE, MARIKO, TACHIBANA, TAKEHIKO

“…KAMBE, M. and TACHIBANA, T. Unrestricted T Cell-Mediated Cytotoxicity to Major Histocompatibility Antigen Generated with Tumor Hybrid Cells. Tohoku J. Exp…”
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