Search Results - "Kambayashi, Satoshi"
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Decreased sensitivity of cyclin-dependent kinase 4/6 inhibitors, palbociclib and abemaciclib to canine lymphoma cells with high p16 protein expression and low retinoblastoma protein phosphorylation
Published in Journal of Veterinary Medical Science (01-01-2023)“…Canine lymphoma/leukemia cell lines with p16 protein expressions: high (17–71 and GL-1) and low (CLBL-1, CLC, Nody-1, and UL-1) were treated in vitro with…”
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2
Comparative Studies of Bioactivities and Chemical Components in Fresh and Black Garlics
Published in Molecules (Basel, Switzerland) (01-05-2024)“…To investigate the bioactivities of fresh garlic and its processed product, black garlic, we conducted comparative analyses of antioxidant, anti-inflammatory,…”
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3
Simultaneous Analysis of the p16 Gene and Protein in Canine Lymphoma Cells and Their Correlation with pRb Phosphorylation
Published in Veterinary sciences (29-07-2022)“…Cyclin-dependent kinase inhibitor p16 (CDKN2A) primarily functions as a negative regulator of the retinoblastoma protein (pRb) pathway to prevent pRb…”
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4
Effect of tolvaptan on hyponatremia in a dog with syndrome of inappropriate secretion of antidiuretic hormone
Published in Journal of Veterinary Medical Science (2023)“…A 1-year-old spayed female Miniature Schnauzer had chronic hyponatremia, accompanied by polyuria and polydipsia. Blood tests and urinalysis revealed severe…”
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5
Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors
Published in Journal of veterinary science (Suwŏn-si, Korea) (01-01-2024)“…The anti-programmed death 1 (PD-1) antibody has led to durable clinical responses in a wide variety of human tumors. We have previously developed the caninized…”
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6
Microparticle-associated tissue factor activity in dogs with disseminated intravascular coagulation
Published in Journal of Veterinary Medical Science (01-01-2020)“…Microparticle (MP)-associated tissue factor (TF) activity in plasma might play a role in human disseminated intravascular coagulation (DIC). The aim of this…”
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7
Tissue factor procoagulant activity in the tumor cell lines and plasma of dogs with various malignant tumors
Published in Journal of Veterinary Medical Science (01-12-2019)“…Hypercoagulability is a common paraneoplastic complication in dogs with various malignant tumors. Importantly, tissue factor procoagulant activity (TF-PCA)…”
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8
MUC5AC and MUC5B expression in canine gallbladder mucocele epithelial cells
Published in Journal of Veterinary Medical Science (2023)“…Gallbladder mucocele (GBM) is one of the most common gallbladder diseases in dogs. Its pathogenesis has not yet been clarified, but excessive accumulation of a…”
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9
Hypoxia inducible factor 1α expression and effects of its inhibitors in canine lymphoma
Published in Journal of Veterinary Medical Science (01-11-2015)“…Hypoxic conditions in various cancers are believed to relate with their malignancy, and hypoxia inducible factor-1α (HIF-1α) has been shown to be a major…”
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10
Improvement of anemia in five dogs with nonregenerative anemia treated with allogeneic adipose-derived stem cells
Published in Veterinary and animal science (01-09-2022)“…•Five canine cases with nonregenerative anemia were included in this study.•All were treated with allogeneic adipose-derived stem cells (ADSCs).•All cases…”
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11
Bimodal immunoglobulin A gammopathy in a cat with feline myeloma-related disorders
Published in Journal of Veterinary Medical Science (01-01-2016)“…A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb was revealed with bimodal monoclonal gammopathy composed of IgA by…”
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12
Blockade of isoprenoids biosynthesis by simvastatin induces autophagy-mediated cell death via downstream c-Jun N-terminal kinase activation and cell cycle dysregulation in canine T-cell lymphoma cells
Published in Research in veterinary science (01-03-2024)“…Statins are inhibitors of the mevalonic acid pathway that mediates cellular metabolism by producing cholesterol and isoprenoids and are widely used in treating…”
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13
Plasma cell‐free DNA in canine lymphoma patients as a novel material for genotyping
Published in Veterinary & comparative oncology (01-06-2024)“…Canine lymphoma is a disease with high morbidity and poor long‐term prognosis, despite a high response rate to chemotherapy. In this study, we focused on…”
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14
Effect of simvastatin on cell proliferation and Ras activation in canine tumour cells
Published in Veterinary & comparative oncology (01-03-2021)“…Statins are inhibitors of the mevalonate cascade that is responsible for cholesterol biosynthesis and the formation of intermediate metabolites, farnesyl…”
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15
Decreased sensitivity of cyclin-dependent kinase 4/6 inhibitors, palbociclib and abemaciclib to canine lymphoma cells with high p16 protein expression and low retinoblastoma protein phosphorylation
Published in Journal of Veterinary Medical Science (2022)“…Canine lymphoma/leukemia cell lines with p16 protein expressions: high (17-71 and GL-1) and low (CLBL-1, CLC, Nody-1, and UL-1) were treated in vitro with…”
Get full text
Journal Article -
16
Effect of tolvaptan on hyponatremia in a dog with syndrome of inappropriate secretion of antidiuretic hormone
Published in Journal of Veterinary Medical Science (2023)“…A 1-year-old spayed female Miniature Schnauzer had chronic hyponatremia, accompanied by polyuria and polydipsia. Blood tests and urinalysis revealed severe…”
Get full text
Journal Article -
17
MUC5AC and MUC5B expression in canine gallbladder mucocele epithelial cells
Published in Journal of Veterinary Medical Science (2023)“…Gallbladder mucocele (GBM) is one of the most common gallbladder diseases in dogs. Its pathogenesis has not yet been clarified, but excessive accumulation of a…”
Get full text
Journal Article -
18
Abstract 3797: Non-invasive identification of tumor cells using near infrared composition imaging system
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract BACKGROUND: Circulating tumor cells (CTCs) are expected to be utilized for decision-making in precision cancer medicine and further elucidation of…”
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Abstract 4149: Increased migration ability of osimertinib-resistant EGFR-T790M mutant non-small-cell lung cancer cells
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Background: A third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) osimertinib is effective against…”
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Journal Article -
20
Proof-of-concept study of the caninized anti-canine programmed death antibody in dogs with advanced non-oral malignant melanoma solid tumors
Published in Journal of veterinary science (Suwŏn-si, Korea) (01-01-2024)“…Background: The anti-programmed death 1 (PD-1) antibody has led to durable clinical responses in a wide variety of human tumors. We have previously developed…”
Get full text
Journal Article