Search Results - "Kamath, Patrick S."

Hepatorenal syndrome: pathophysiology, diagnosis, and management by Simonetto, Douglas A, Gines, Pere, Kamath, Patrick S

“…ABSTRACT Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with cirrhosis, is characterized by reduction in renal blood…”
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Management of Antithrombotic Therapy in Patients Undergoing Invasive Procedures by Baron, Todd H, Kamath, Patrick S, McBane, Robert D

“…When patients receiving anticoagulation therapy undergo invasive procedures, management requires an individualized assessment of the risk of bleeding versus…”
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ACG Clinical Guideline: Disorders of the Hepatic and Mesenteric Circulation by Simonetto, Douglas A., Singal, Ashwani K., Garcia-Tsao, Guadalupe, Caldwell, Stephen H., Ahn, Joseph, Kamath, Patrick S.

“…Disorders of the mesenteric, portal, and hepatic veins and mesenteric and hepatic arteries have important clinical consequences and may lead to acute liver…”
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Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial by Cavallin, Marta, Kamath, Patrick S., Merli, Manuela, Fasolato, Silvano, Toniutto, Pierluigi, Salerno, Francesco, Bernardi, Mauro, Romanelli, Roberto Giulio, Colletta, Cosimo, Salinas, Freddy, Di Giacomo, Antonio, Ridola, Lorenzo, Fornasiere, Ezio, Caraceni, Paolo, Morando, Filippo, Piano, Salvatore, Gatta, Angelo, Angeli, Paolo

“…Hepatorenal syndrome (HRS), a serious complication of cirrhosis, is associated with high mortality without treatment. Terlipressin with albumin is effective in…”
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Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension by Hilscher, Moira B., Sehrawat, Tejasav, Arab, Juan P., Zeng, Zhutian, Gao, Jinhang, Liu, Mengfei, Kostallari, Enis, Gao, Yandong, Simonetto, Douglas A., Yaqoob, Usman, Cao, Sheng, Revzin, Alexander, Beyder, Arthur, Wang, Rong A., Kamath, Patrick S., Kubes, Paul, Shah, Vijay H.

“…Mechanical forces contribute to portal hypertension (PHTN) and fibrogenesis. We investigated the mechanisms by which forces are transduced by liver sinusoidal…”
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Survival in infection‐related acute‐on‐chronic liver failure is defined by extrahepatic organ failures by Bajaj, Jasmohan S., O'Leary, Jacqueline G., Reddy, K. Rajender, Wong, Florence, Biggins, Scott W., Patton, Heather, Fallon, Michael B., Garcia‐Tsao, Guadalupe, Maliakkal, Benedict, Malik, Raza, Subramanian, Ram M., Thacker, Leroy R., Kamath, Patrick S., the North American Consortium for the Study of End-stage Liver Disease (NACSELD)

“…Infections worsen survival in cirrhosis; however, simple predictors of survival in infection‐related acute‐on‐chronic liver failure (I‐ACLF) derived from…”
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Liver Disease in Patients After the Fontan Operation by Pundi, Krishna, BS, Pundi, Kavitha N., MD, Kamath, Patrick S., MD, Cetta, Frank, MD, Li, Zhuo, BS, Poterucha, Joseph T., MD, Driscoll, David J., MD, Johnson, Jonathan N., MD

“…We reviewed records of all patients with an initial Fontan operation or revision from 1973 to 2012 at our institution (n = 1,138); 195 patients had…”
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Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles by Verma, Vikas K, Li, Haiyang, Wang, Ruisi, Hirsova, Petra, Mushref, Malek, Liu, Yaming, Cao, Sheng, Contreras, Patricia C, Malhi, Harmeet, Kamath, Patrick S, Gores, Gregory J, Shah, Vijay H

“…Graphical abstract…”
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Inverse Association of Telomere Length With Liver Disease and Mortality in the US Population by Rattan, Puru, Penrice, Daniel D., Ahn, Joseph C., Ferrer, Alejandro, Patnaik, Mrinal, Shah, Vijay H., Kamath, Patrick S., Mangaonkar, Abhishek A., Simonetto, Douglas A.

“…Physiologic aging leads to attrition of telomeres and replicative senescence. An acceleration of this process has been hypothesized in the progression of…”
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Hyponatremia and Mortality among Patients on the Liver-Transplant Waiting List by Kim, W. Ray, Biggins, Scott W, Kremers, Walter K, Wiesner, Russell H, Kamath, Patrick S, Benson, Joanne T, Edwards, Erick, Therneau, Terry M

“…The Model for End-Stage Liver Disease (MELD) uses bilirubin, the international normalized ratio for prothrombin time, and creatinine to estimate the risk of…”
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Grand Rounds: Alcoholic Hepatitis by Singal, Ashwani K., Louvet, Alexandre, Shah, Vijay H., Kamath, Patrick S.

“…A 33-year-old Caucasian male was admitted to hospital with recent onset of jaundice of 2–3 weeks duration. He reported heavy use of alcohol for the last…”
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The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis by Puri, Puneet, Liangpunsakul, Suthat, Christensen, Jeffrey E., Shah, Vijay H., Kamath, Patrick S., Gores, Gregory J., Walker, Susan, Comerford, Megan, Katz, Barry, Borst, Andrew, Yu, Qigui, Kumar, Divya P., Mirshahi, Faridoddin, Radaeva, Svetlana, Chalasani, Naga P., Crabb, David W., Sanyal, Arun J.

“…Intestinal dysbiosis is implicated in alcoholic hepatitis (AH). However, changes in the circulating microbiome, its association with the presence and severity…”
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Incidence and Risk Factors for Adverse Events Related to Image-Guided Liver Biopsy by Boyum, James H., MD, Atwell, Thomas D., MD, Schmit, Grant D., MD, Poterucha, John J., MD, Schleck, Cathy D., BS, Harmsen, W. Scott, MS, Kamath, Patrick S., MD

“…Abstract Objective To determine the incidence of major adverse events related to a large volume of image-guided liver biopsies performed at our institution…”
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Acute-on-chronic liver failure in cirrhosis by Arroyo, Vicente, Moreau, Richard, Kamath, Patrick S., Jalan, Rajiv, Ginès, Pere, Nevens, Frederik, Fernández, Javier, To, Uyen, García-Tsao, Guadalupe, Schnabl, Bernd

“…The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and North America, the term is generally applied according to the European…”
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Management of Hepatic Encephalopathy in the Hospital by Leise, Michael D., MD, Poterucha, John J., MD, Kamath, Patrick S., MD, Kim, W. Ray, MD

“…Abstract Hepatic encephalopathy (HE) develops in up to 50% of patients with cirrhosis and is a feature of decompensated cirrhosis. With the goal of reviewing…”
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Alcoholic Hepatitis: Current Challenges and Future Directions by Singal, Ashwani K, Kamath, Patrick S, Gores, Gregory J, Shah, Vijay H

“…Alcoholic hepatitis is a distinct clinical syndrome among people with chronic and active alcohol abuse, with a potential for 30%–40% mortality at 1 month among…”
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Mesenteric Venous Thrombosis by Singal, Ashwani K., MD, Kamath, Patrick S., MD, Tefferi, Ayalew, MD

“…Abstract The prevalence of mesenteric venous thrombosis has increased over the past 2 decades with the routine use of contrast-enhanced computed tomography…”
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Alcohol‐Related Liver Disease: Areas of Consensus, Unmet Needs and Opportunities for Further Study by Szabo, Gyongyi, Kamath, Patrick S., Shah, Vijay H., Thursz, Mark, Mathurin, Philippe, Addolorato, Giovanni, Bataller, Ramon, Burra, Patrizia, Castera, Laurent, Cortez Pinto, Helena, Diehl, Anna Mae, Gao, Bin, Gilmore, Sir Ian, Hampe, Jochen, Jürgen, Rehm, Karin, Michael, Krag, Alexander, Leon, David, Leptak, Christopher, Louvet, Alexandre, Lucey, Michael, McClain, Craig, Nagy, Laura, Pageaux, Georges‐Philippe, Sanyal, Arun, Schnabl, Bernd, Tiniakos, Dina, Trautwein, Christian, Tsukamoto, Hidekazu

“…A joint meeting of the European Association for the Study of the Liver (EASL) and the American Association for the Study of Liver Diseases (AASLD) was held in…”
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Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces by Simonetto, Douglas A., Yang, Hui‐yin, Yin, Meng, de Assuncao, Thiago M., Kwon, Jung Hee, Hilscher, Moira, Pan, Shuchong, Yang, Liu, Bi, Yan, Beyder, Arthur, Cao, Sheng, Simari, Robert D., Ehman, Richard, Kamath, Patrick S., Shah, Vijay H.

“…Chronic passive hepatic congestion (congestive hepatopathy) leads to hepatic fibrosis; however, the mechanisms involved in this process are not well…”
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Rivaroxaban and Apixaban for Initial Treatment of Acute Venous Thromboembolism of Atypical Location by Janczak, Dawid T., Mimier, Malgorzata K., McBane, Robert D., Kamath, Patrick S., Simmons, Benjamin S., Bott-Kitslaar, Dalene M., Lenz, Charles J., Vargas, Emily R., Hodge, David O., Wysokinski, Waldemar E.

“…To assess the outcome of direct oral anticoagulants (DOACs), specifically Xa inhibitors: rivaroxaban and apixaban, for the treatment of venous thromboembolism…”
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