Search Results - "Kamarck, Michael E."

Building biomanufacturing capacity-the chapter and verse by Kamarck, Michael E

“…Biopharmaceutical manufacturing capacity has moved through three discrete chapters in its 25-year history. Could the next chapter herald formal…”
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The major human rhinovirus receptor is ICAM-1 by Greve, J M, Davis, G, Meyer, A M, Forte, C P, Yost, S C, Marlor, C W, Kamarck, M E, McClelland, A

“…The major human rhinovirus receptor has been identified with monoclonal antibodies that inhibit rhinovirus infection. These monoclonal antibodies recognize a…”
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Fluorescence-activated cell sorting of hybrid and transfected cells by Kamarck, M E

“…Mouse cells containing human surface antigen genes introduced by cell hybridization or DNA transfection can be labeled by indirect immunofluorescence and…”
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Sequential NMR resonance assignment and structure determination of the Kunitz-type inhibitor domain of the Alzheimer's .beta.-amyloid precursor protein by Heald, Sarah L, Tilton, Robert F, Hammond, Lisa J, Lee, Alice, Bayney, Richard M, Kamarck, Michael E, Ramabhadran, Triprayar V, Dreyer, Robert N, Davis, Gary

“…Certain precursor proteins (APP751 and APP770) of the amyloid beta-protein (AP) present in Alzheimer's disease contain a Kunitz-type serine protease inhibitor…”
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In the Quest to Manage Capacity, Biology Trumps Stainless Steel by Kamarck, Michael E

“…After 20 years of experience, most biotech companies have discovered that integrating process development and manufacturing into a single organization saves…”
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Expression of Thymocyte Surface Alloantigens in the Fetal Mouse Thymus in vivo and in Organ Culture by Kamarck, Michael E, Gottlieb, Paul D

“…Cell proliferation and surface alloantigen expression were monitored during development of the fetal mouse thymus in vivo from day 13 of gestation until birth,…”
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Biotech Manufacturing Grows Up by Kamarck, Michael E, Hann, Louane E, Adamson, S Robert

“…In addition to the inherent difficulties associated with a production platform based on molecular and cellular biology, biopharmaceutical manufacturing always…”
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Carcinoembryonic Antigens: Alternative Splicing Accounts for the Multiple mRNAs That Code for Novel Members of the Carcinoembryonic Antigen Family by Barnett, Thomas R., Kretschmer, Axel, Austen, Douglas A., Goebel, Scott J., Hart, John T., Elting, James J., Kamarck, Michael E.

“…The recent cloning of complete cDNAs encoding carcinoembryonic antigen (CEA) and nonspecific cross-reacting antigen has revealed the existence of a new gene…”
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Processing of the Pre‐β‐amyloid Protein by Cathepsin d is Enhanced by a Familial Alzheimer's Disease Mutation by Dreyer, Robert N., Bausch, Kathryn M., Fracasso, Paul, Hammond, Lisa J., Wunderlich, David, Wirak, Dana O., Davis, Gary, Brini, Carla M., Buckholz, Thomas M., König, Gerhard, Kamarck, Michael E., Tamburini, Paul P.

“…A major pre‐β‐amyloid protein695 (APP695) processing activity from Alzheimer's disease brain extracts was identified and found to be indistinguishable from the…”
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A fluorometric assay for HIV-protease activity using high-performance liquid chromatography by Tamburini, P P, Dreyer, R N, Hansen, J, Letsinger, J, Elting, J, Gore-Willse, A, Dally, R, Hanko, R, Osterman, D, Kamarck, M E

“…A rapid sensitive method for the quantification of in vitro HIV-protease activity has been developed on the basis of the endoproteolytic conversion of…”
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Identification of Human Genomic Clones Coding the Major Histocompatibility Antigens HLA-A2 and HLA-B7 by DNA-Mediated Gene Transfer by Barbosa, James A., Kamarck, Michael E., Biro, P. Andrew, Weissman, Sherman M., Ruddle, Frank H.

“…We have screened a large number of isolated human genomic clones that hybridize to a cloned HLA cDNA probe for their ability to direct the synthesis of HLA-A,…”
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cDNA cloning and mapping of the human creatine kinase M gene to 19q13 by NIGRO, J. M, SCHWEINFEST, C. W, MARTIN-DELEON, P, RAJKOVIC, A, PAVLOVIC, J, JAMAL, S, DOTTIN, R. P, HART, J. T, KAMARCK, M. E, RAE, P. M. M, CARTY, M. D

“…We describe the first isolation of a human creatine kinase M cDNA clone and its mapping of the gene to human chromosome 19. A human creatine kinase M cDNA…”
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In the quest to manage capacity, biology trumps stainless steel: science, improved processes, and standardization are transforrning the industry and driving down costs by Kamarck, Michael E

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Molecular cloning of receptor genes by transfection by McClelland, A, Kamarck, M E, Ruddle, F H

“…We have described a transfection method for the isolation of surface antigen genes which requires no mRNA or protein purification. Application of this…”
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Somatic cell genetic analysis of HLA-A, B, C and human? 2-microglobulin expression by Kamarck, Michael E., Barbosa, James A., Ruddle, Frank H.

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Somatic cell hybrid mapping panels by Kamarck, M E, Barker, P E, Miller, R L, Ruddle, F H

“…The recent advances in human gene mapping have been largely due to the development of interspecies cell hybrids containing human chromosomes and their…”
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Alterations in expression of murine thymocyte proteins and glycoproteins during fetal thymus development by Kamarck, M E, Gottlieb, P D

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The gene coding the human S11 surface antigens maps between the loci for HPRT and G6PD on the X-chromosome by Kamarck, M E, Macyko, C A, Cunningham, A C, Ruddle, F H

“…The human S11 surface antigens are expressed on fibroblasts and are coded by a gene on the X-chromosome. We have regionally mapped this gene by examining S11…”
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Production of interspecies T cell hybrids which retain differentiation specific surface antigens by Messer Peters, P G, Kamarck, M E, Ruddle, F H

“…Genetic mapping of differentiation specific surface antigens has been hampered by difficulty in preparation of interspecies hybrid cells which continue to…”
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Biotech manufacturing grows up: the industry, now 30 years old, is undergoing an important transition by Kamarck, Michael E, Hann, Louane E, Adamson, S. Robert

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