Search Results - "Kamali, Afrand"

In vitro and in vivo catabolism of TAK-164, a gcc-targeted antibody-drug conjugate by Bolleddula, Jayaprakasam, Shadid, Mohammad, Shah, Abhi, Kamali, Afrand, Smith, Mike, Abu-Yousif, Adnan, Xia, Cindy, Chowdhury, Swapan K.

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Surface Sampling by Spray-Desorption Followed by Collection for Chemical Analysis by Venter, Andre R, Kamali, Afrand, Jain, Shashank, Bairu, Semere

“…Desorption electrospray ionization (DESI) directly analyzes soluble chemical components present on surfaces when a pneumatically assisted electrospray is…”
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Pharmacokinetics and Catabolism of [ 3 H]TAK-164, a Guanylyl Cyclase C Targeted Antibody-Drug Conjugate by Bolleddula, Jayaprakasam, Shah, Abhi, Shadid, Mohammad, Kamali, Afrand, Smith, Michael D, Chowdhury, Swapan K

“…TAK-164 is an antibody-drug conjugate (ADC) comprising human anti-guanylyl cyclase C (GCC) monoclonal antibody conjugated to indolinobenzodiazepine DNA…”
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An LC/MS based method to quantify DNA adduct in tumor and organ tissues by Li, Chao, Dong, Linlin, Kamali, Afrand, Sugimoto, Hiroshi, Abdul-Hadi, Kojo, Chen, Susan, Abu-Yousif, Adnan, Qian, Mark G.

“…Highly potent DNA damaging agents have become a key class of toxins for antibody-drug conjugate (ADC) based targeted therapy. However, until recently, no…”
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Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody–Drug Conjugate in Patient-derived Xenografts by Abu-Yousif, Adnan O., Cvet, Donna, Gallery, Melissa, Bannerman, Bret M., Ganno, Michelle L., Smith, Michael D., Lai, Katharine C., Keating, Thomas A., Stringer, Bradley, Kamali, Afrand, Eng, Kurt, Koseoglu, Secil, Zhu, Andy, Xia, Cindy Q., Landen, Melissa Saylor, Borland, Maria, Robertson, Robbie, Bolleddula, Jayaprakasam, Qian, Mark G., Fretland, Jennifer, Veiby, O. Petter

“…Abstract Guanylyl cyclase C (GCC) is a unique therapeutic target with expression restricted to the apical side of epithelial cell tight junctions thought to be…”
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Abstract B120: TAK-164, a GCC-targeted antibody-drug conjugate (ADC) for the treatment of colorectal cancers and other GI malignancies by Abu-Yousif, Adnan O., Bannerman, Bret M., Cvet, Donna, Gallery, Melissa, Ganno, Michelle L., Smith, Michael D., Lai, Katharine C., Keating, Thomas A., Bolleddula, Jayaprakasam, Stringer, Bradley, Qian, Mark G., Kamali, Afrand, Eng, Kurt, Koseoglu, Secil, Xia, Cindy Q., Veiby, O. Petter

“…Abstract TAK-164 is an antibody-drug conjugate comprising a full-length, fully human IgG1 monoclonal antibody (mAb) directed towards the extracellular domain…”
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Metabolomic profiling of lignocellulosic biomass process streams by Kamali Sarvestani, Afrand

“…Practical advances in conversion of lignocellulosic biomass to bioethanol require improvement of current knowledge about the composition and chemical diversity…”
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