Search Results - "Kamal, Md Zahid"

Role of active site rigidity in activity: MD simulation and fluorescence study on a lipase mutant by Kamal, Md Zahid, Mohammad, Tabrez Anwar Shamim, Krishnamoorthy, G, Rao, Nalam Madhusudhana

“…Relationship between stability and activity of enzymes is maintained by underlying conformational flexibility. In thermophilic enzymes, a decrease in…”
Get full text

Thermostable Bacillus subtilis Lipases: In Vitro Evolution and Structural Insight by Ahmad, Shoeb, Kamal, Md. Zahid, Sankaranarayanan, Rajan, Rao, N. Madhusudhana

“…In vitro evolution methods are now being routinely used to identify protein variants with novel and enhanced properties that are difficult to achieve using…”
Get full text

Synthesis and Transfection Efficiency of Cationic Oligopeptide Lipids: Role of Linker by Gopal, Vijaya, Xavier, Jennifer, Kamal, Md. Zahid, Govindarajan, Srinath, Takafuji, Makoto, Soga, Shuta, Ueno, Takayuki, Ihara, Hirotaka, Rao, Nalam M

“…In the design of new cationic lipids for gene transfection, the chemistry of linkers is widely investigated from the viewpoint of biodegradation and less from…”
Get full text

Lipase in aqueous‐polar organic solvents: Activity, structure, and stability by Kamal, Md. Zahid, Yedavalli, Poornima, Deshmukh, Mandar V., Rao, Nalam Madhusudhana

“…Studying alterations in biophysical and biochemical behavior of enzymes in the presence of organic solvents and the underlying cause(s) has important…”
Get full text

A computational search for lipases that can preferentially hydrolyze long-chain omega-3 fatty acids from fish oil triacylglycerols by Kamal, Md. Zahid, Barrow, Colin J., Rao, Nalam Madhusudhana

“…•Omega-3 fatty acid containing triglycerides were docked on all lipases with known structure.•Both non-covalent and covalent docking experiments were…”
Get full text

In Vitro Evolved Non-Aggregating and Thermostable Lipase: Structural and Thermodynamic Investigation by Kamal, Md. Zahid, Ahmad, Shoeb, Molugu, Trivikram Rao, Vijayalakshmi, Amash, Deshmukh, Mandar V., Sankaranarayanan, Rajan, Rao, Nalam Madhusudhana

“…Rational and in vitro evolutionary approaches to improve either protein stability or aggregation resistance were successful, but empirical rules for…”
Get full text

Binding of bis-ANS to Bacillus subtilis lipase: A combined computational and experimental investigation by Kamal, Md. Zahid, Ali, Jamshaid, Rao, Nalam Madhusudhana

“…8-Anilino-1-naphthalene sulfonate (ANS) and its covalent dimer bis-ANS are widely used for titrating hydrophobic surfaces of proteins. Interest to understand…”
Get full text

Stability curves of laboratory evolved thermostable mutants of a Bacillus subtilis lipase by Kamal, Md. Zahid, Ahmad, Shoeb, Yedavalli, Poornima, Rao, Nalam Madhusudhana

“…Shape of the protein stability curves changes to achieve higher melting temperature. Broadly, these changes have been classified as upward shift (increased ∆ G…”
Get full text

Stabilizing effect of polyols is sensitive to inherent stability of protein by Kamal, Md. Zahid, Ahmad, Shoeb, Rao, Nalam Madhusudhana

“…In studies on polyol-mediated protein stabilization, the polyols are the preferred variable and less importance is given to the intrinsic properties of the…”
Get full text