Search Results - "Kamal, Khaled Y"
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Cellular and Molecular Signaling Meet the Space Environment
Published in International journal of molecular sciences (22-03-2023)“…During space missions that travel beyond the cocoon of the Earth's magnetosphere, astronauts are subjected to the microgravity and radiation stressors of outer…”
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The Impact of SRT2104 on Skeletal Muscle Mitochondrial Function, Redox Biology, and Loss of Muscle Mass in Hindlimb Unloaded Rats
Published in International journal of molecular sciences (01-07-2023)“…Mechanical unloading during microgravity causes skeletal muscle atrophy and impairs mitochondrial energetics. The elevated production of reactive oxygen…”
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Exogenously Applied Gibberellic Acid Enhances Growth and Salinity Stress Tolerance of Maize through Modulating the Morpho-Physiological, Biochemical and Molecular Attributes
Published in Biomolecules (Basel, Switzerland) (09-07-2021)“…Soil salinity is the major limiting factor restricting plant growth and development. Little is known about the comparative and combined effects of gibberellic…”
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Nox2 Inhibition Regulates Stress Response and Mitigates Skeletal Muscle Fiber Atrophy during Simulated Microgravity
Published in International journal of molecular sciences (23-03-2021)“…Insufficient stress response and elevated oxidative stress can contribute to skeletal muscle atrophy during mechanical unloading (e.g., spaceflight and…”
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Bioreactor development for skeletal muscle hypertrophy and atrophy by manipulating uniaxial cyclic strain: proof of concept
Published in NPJ microgravity (11-06-2024)“…Skeletal muscles overcome terrestrial, gravitational loading by producing tensile forces that produce movement through joint rotation. Conversely, the…”
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Evaluation of Simulated Microgravity Environments Induced by Diamagnetic Levitation of Plant Cell Suspension Cultures
Published in Microgravity science and technology (01-06-2016)“…Ground-Based Facilities (GBF) are essetial tools to understand the physical and biological effects of the absence of gravity and they are necessary to prepare…”
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Use of microgravity simulators for plant biological studies
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2015)“…Simulated microgravity and partial gravity research on Earth is highly convenient for every space biology researcher due to limitations of access to…”
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Evaluation of growth and nutritional value of Brassica microgreens grown under red, blue and green LEDs combinations
Published in Physiologia plantarum (01-08-2020)“…Microgreens are rich functional crops with valuable nutritional elements that have health benefits when used as food supplements. Growth characterization,…”
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Differential transcriptional profile through cell cycle progression in Arabidopsis cultures under simulated microgravity
Published in Genomics (San Diego, Calif.) (01-12-2019)“…Plant cell proliferation is affected by microgravity during spaceflight, but involved molecular mechanisms, key for space agronomy goals, remain unclear. To…”
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Simulated microgravity, Mars gravity, and 2g hypergravity affect cell cycle regulation, ribosome biogenesis, and epigenetics in Arabidopsis cell cultures
Published in Scientific reports (23-04-2018)“…Gravity is the only component of Earth environment that remained constant throughout the entire process of biological evolution. However, it is still unclear…”
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Modulation of cell cycle progression and chromatin dynamic as tolerance mechanisms to salinity and drought stress in maize
Published in Physiologia plantarum (01-06-2021)“…Salinity and drought are the major abiotic stresses that disturb several aspects of maize plants growth at the cellular level, one of these aspects is cell…”
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Cell cycle acceleration and changes in essential nuclear functions induced by simulated microgravity in a synchronized Arabidopsis cell culture
Published in Plant, cell and environment (01-02-2019)“…Zero gravity is an environmental challenge unknown to organisms throughout evolution on Earth. Nevertheless, plants are sensitive to altered gravity, as…”
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Sphingolipid-induced cell death in Arabidopsis is negatively regulated by the papain-like cysteine protease RD21
Published in Plant science (Limerick) (01-03-2019)“…•RD21 is activated in Arabidopis cultured cell in response to PHS.•RD21 is activated in Arabidopsis leaves in response to fumonisin B1.•RD21 behaves as a…”
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Use of Reduced Gravity Simulators for Plant Biological Studies
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Simulated microgravity and partial gravity research on Earth is a necessary complement to space research in real microgravity due to limitations of access to…”
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Proper selection of 1 g controls in simulated microgravity research as illustrated with clinorotated plant cell suspension cultures
Published in Life sciences in space research (01-04-2015)“…Understanding the physical and biological effects of the absence of gravity is necessary to conduct operations on space environments. It has been previously…”
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Embedding Arabidopsis Plant Cell Suspensions in Low-Melting Agarose Facilitates Altered Gravity Studies
Published in Microgravity science and technology (01-02-2017)“…Gravity plays a role in modulating plant growth and development and its alteration induces changes in these processes. Microgravity research has recently been…”
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Evaluating deficit irrigation scheduling strategies to improve yield and water productivity of maize in arid environment using simulation
Published in Agricultural water management (30-04-2021)“…Water scarcity and rising temperatures are creating serious concerns over the sustainability of agriculture systems in arid regions of the Middle East and…”
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A second space age spanning omics, platforms and medicine across orbits
Published in Nature (London) (29-08-2024)“…The recent acceleration of commercial, private and multi-national spaceflight has created an unprecedented level of activity in low Earth orbit, concomitant…”
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