Search Results - "Kamada, Katsuhiko"

Combing Chromosomal DNA Mediated by the SMC Complex: Structure and Mechanisms by Kamada, Katsuhiko, Barillà, Daniela

“…Genome maintenance requires various nucleoid‐associated factors in prokaryotes. Among them, the SMC (Structural Maintenance of Chromosomes) protein has been…”
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Overall Shapes of the SMC-ScpAB Complex Are Determined by Balance between Constraint and Relaxation of Its Structural Parts by Kamada, Katsuhiko, Su'etsugu, Masayuki, Takada, Hiraku, Miyata, Makoto, Hirano, Tatsuya

“…The SMC-ScpAB complex plays a crucial role in chromosome organization and segregation in many bacteria. It is composed of a V-shaped SMC dimer and an ScpAB…”
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Conformational Change in the Catalytic Site of the Ribonuclease YoeB Toxin by YefM Antitoxin by Kamada, Katsuhiko, Hanaoka, Fumio

“…The eubacterial chromosome encodes various addiction modules that control global levels of translation through RNA degradation. Crystal structures of the…”
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Molecular Basis of SMC ATPase Activation: Role of Internal Structural Changes of the Regulatory Subcomplex ScpAB by Kamada, Katsuhiko, Miyata, Makoto, Hirano, Tatsuya

“…In many bacteria, a homodimer of structural-maintenance-of-chromosomes proteins associates with two regulatory subunits (known as ScpA and ScpB), assembling a…”
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Structure of the human GINS complex and its assembly and functional interface in replication initiation by Kamada, Katsuhiko, Kubota, Yumiko, Arata, Toshiaki, Shindo, Yosuke, Hanaoka, Fumio

“…The eukaryotic GINS complex is essential for the establishment of DNA replication forks and replisome progression. We report the crystal structure of the human…”
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The mini-chromosome maintenance (Mcm) complexes interact with DNA polymerase α-primase and stimulate its ability to synthesize RNA primers by You, Zhiying, De Falco, Mariarosaria, Kamada, Katsuhiko, Pisani, Francesca M, Masai, Hisao

“…The Mini-chromosome maintenance (Mcm) proteins are essential as central components for the DNA unwinding machinery during eukaryotic DNA replication. DNA…”
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Potent SARS-CoV-2 neutralizing antibodies with therapeutic effects in two animal models by Takeshita, Masaru, Fukuyama, Hidehiro, Kamada, Katsuhiko, Matsumoto, Takehisa, Makino-Okamura, Chieko, Uchikubo-Kamo, Tomomi, Tomabechi, Yuri, Hanada, Kazuharu, Moriyama, Saya, Takahashi, Yoshimasa, Ishigaki, Hirohito, Nakayama, Misako, Nguyen, Cong Thanh, Kitagawa, Yoshinori, Itoh, Yasushi, Imai, Masaki, Maemura, Tadashi, Furusawa, Yuri, Ueki, Hiroshi, Iwatsuki-Horimoto, Kiyoko, Ito, Mutsumi, Yamayoshi, Seiya, Kawaoka, Yoshihiro, Shirouzu, Mikako, Ishii, Makoto, Saya, Hideyuki, Kondo, Yasushi, Kaneko, Yuko, Suzuki, Katsuya, Fukunaga, Koichi, Takeuchi, Tsutomu

“…The use of therapeutic neutralizing antibodies against SARS-CoV-2 infection has been highly effective. However, there remain few practical antibodies against…”
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Potent neutralizing broad-spectrum antibody against SARS-CoV-2 generated from dual-antigen-specific B cells from convalescents by Takeshita, Masaru, Fukuyama, Hidehiro, Kamada, Katsuhiko, Matsumoto, Takehisa, Makino-Okamura, Chieko, Lin, Qingshun, Sakuma, Machie, Kawahara, Eiki, Yamazaki, Isato, Uchikubo-Kamo, Tomomi, Tomabechi, Yuri, Hanada, Kazuharu, Hisano, Tamao, Moriyama, Saya, Takahashi, Yoshimasa, Ito, Mutsumi, Imai, Masaki, Maemura, Tadashi, Furusawa, Yuri, Yamayoshi, Seiya, Kawaoka, Yoshihiro, Shirouzu, Mikako, Ishii, Makoto, Saya, Hideyuki, Kondo, Yasushi, Kaneko, Yuko, Suzuki, Katsuya, Fukunaga, Koichi, Takeuchi, Tsutomu

“…Several antibody therapeutics have been developed against SARS-CoV-2; however, they have attenuated neutralizing ability against variants. In this study, we…”
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A Modular Cross-Linking Approach for Exploring Protein Interactions by Trester-Zedlitz, Michelle, Kamada, Katsuhiko, Burley, Stephen K, Fenyö, David, Chait, Brian T, Muir, Tom W

“…A method is described for the elucidation of protein−protein interactions using novel cross-linking reagents and mass spectrometry. The method incorporates (1)…”
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Structure and Mutagenesis Studies of the C-terminal Region of Licensing Factor Cdt1 Enable the Identification of Key Residues for Binding to Replicative Helicase Mcm Proteins by Jee, JunGoo, Mizuno, Takeshi, Kamada, Katsuhiko, Tochio, Hidehito, Chiba, Yasumasa, Yanagi, Ken-ichiro, Yasuda, Gentaro, Hiroaki, Hidekazu, Hanaoka, Fumio, Shirakawa, Masahiro

“…In eukaryotes, DNA replication is fired once in a single cell cycle before cell division starts to maintain stability of the genome. This event is tightly…”
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Crystal Structure of Negative Cofactor 2 Recognizing the TBP-DNA Transcription Complex by Kamada, Katsuhiko, Shu, Fong, Chen, Hua, Malik, Sohail, Stelzer, Gertraud, Roeder, Robert G., Meisterernst, Michael, Burley, Stephen K.

“…The X-ray structure of a ternary complex of Negative Cofactor 2 (NC2), the TATA box binding protein (TBP), and DNA has been determined at 2.6 Å resolution. The…”
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S3-2 Structural biology of bacterial programmed cell death by KAMADA Katsuhiko

“…Plasmid possess genetic elements encoding toxin-antitoxin pairs, known as addiction modules, which were originally proposed to control post-segregational…”
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Molecular Mechanism of Recruitment of TFIIF-Associating RNA Polymerase C-Terminal Domain Phosphatase (FCP1) by Transcription Factor IIF by Kamada, Katsuhiko, Roeder, Robert G., Burley, Stephen K.

“…After mRNA transcription termination in eukaryotes, the hyperphosphorylated form of RNA polymerase II (pol II0) must be recycled by TFIIF-associating…”
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The GINS complex: structure and function by Kamada, Katsuhiko

“…Eukaryotic chromosomal DNA replication is controlled by a highly ordered series of steps involving multiple proteins at replication origins. The eukaryotic…”
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Crystal Structure of the C-Terminal Domain of the RAP74 Subunit of Human Transcription Factor IIF by Kamada, Katsuhiko, De Angelis, Jacqueline, Roeder, Robert G., Burley, Stephen K.

“…The x-ray structure of a C-terminal fragment of the RAP74 subunit of human transcription factor (TF) IIF has been determined at 1.02-Å resolution. The α/β…”
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YoeB-ribosome structure: a canonical RNase that requires the ribosome for its specific activity by Feng, Shu, Chen, Yun, Kamada, Katsuhiko, Wang, Han, Tang, Kai, Wang, Meitian, Gao, Yong-Gui

“…As a typical endoribonuclease, YoeB mediates cellular adaptation in diverse bacteria by degrading mRNAs on its activation. Although the catalytic core of YoeB…”
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Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognition by Kamada, Katsuhiko, Hanaoka, Fumio, Burley, Stephen K

“…A structure of the Escherichia coli chromosomal MazE/MazF addiction module has been determined at 1.7 A resolution. Addiction modules consist of stable toxin…”
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The Mini-Chromosome Maintenance by You, Zhiying, De Falco, Mariarosaria, Kamada, Katsuhiko, Pisani, Francesca M, Masai, Hisao

“…The Mini-chromosome maintenance (Mcm) proteins are essential as central components for the DNA unwinding machinery during eukaryotic DNA replication. DNA…”
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The Mini-Chromosome Maintenance Complexes Interact with DNA Polymerase [alpha]-Primase and Stimulate Its Ability to Synthesize RNA Primers by You, Zhiying, De Falco, Mariarosaria, Kamada, Katsuhiko, Pisani, Francesca M, Masai, Hisao

“…The Mini-chromosome maintenance (Mcm) proteins are essential as central components for the DNA unwinding machinery during eukaryotic DNA replication. DNA…”
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Structure of a canonical RNase YoeB bound to the ribosome by Chen, Yun, Feng, Shu, Kamada, Katsuhiko, Wang, Han, Tang, Kai, Wang, Meitian, Gao, Yonggui

“…Abstract only As a typical endoribonuclease, YoeB mediates cellular adaptation in diverse bacteria by degrading mRNAs on its activation. Although the catalytic…”
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