Search Results - "Kam, Jaimie Hoh"

Does photobiomodulation require glucose to work effectively? by Hoh Kam, Jaimie, Mitrofanis, John

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Viewing ageing eyes: diverse sites of amyloid Beta accumulation in the ageing mouse retina and the up-regulation of macrophages by Hoh Kam, Jaimie, Lenassi, Eva, Jeffery, Glen

“…Amyloid beta (Aβ) accumulates in the ageing central nervous system and is associated with a number of age-related diseases, including age-related macular…”
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Glucose Improves the Efficacy of Photobiomodulation in Changing ATP and ROS Levels in Mouse Fibroblast Cell Cultures by Hoh Kam, Jaimie, Mitrofanis, John

“…In this study, we tested the idea that photobiomodulation-the application of red to near infrared light (~λ = 600-1300 nm) to body tissues-is more effective in…”
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The 3D organisation of mitochondria in primate photoreceptors by Hayes, Matthew J., Tracey-White, Dhani, Kam, Jaimie Hoh, Powner, Michael B., Jeffery, Glen

“…Vertebrate photoreceptors contain large numbers of closely-packed mitochondria which sustain the high metabolic demands of these cells. These mitochondria…”
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Complement Component C3 Plays a Critical Role in Protecting the Aging Retina in a Murine Model of Age-Related Macular Degeneration by Hoh Kam, Jaimie, Lenassi, Eva, Malik, Talat H, Pickering, Matthew C, Jeffery, Glen

“…Complement component C3 is the central complement component and a key inflammatory protein activated in age-related macular degeneration (AMD). AMD is…”
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The effect of photobiomodulation on the brain during wakefulness and sleep by Moro, Cecile, Valverde, Audrey, Dole, Marjorie, Hoh Kam, Jaimie, Hamilton, Catherine, Liebert, Ann, Bicknell, Brian, Benabid, Alim-Louis, Magistretti, Pierre, Mitrofanis, John

“…Over the last seventy years or so, many previous studies have shown that photobiomodulation, the use of red to near infrared light on body tissues, can improve…”
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Do astrocytes respond to light, sound, or electrical stimulation? by Naour, Audrey, Beziat, Emilien, Kam, Jaimie, Magistretti, Pierre, Benabid, Alim-Louis, Mitrofanis, John

“…Astrocytes are not only the most populous cell type in the human brain, but they also have the most extensive and diverse sets of connections, across synapses,…”
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Systemic administration of Abeta mAb reduces retinal deposition of Abeta and activated complement C3 in age-related macular degeneration mouse model by Catchpole, Ian, Germaschewski, Volker, Hoh Kam, Jaimie, Lundh von Leithner, Peter, Ford, Susannah, Gough, Gerald, Adamson, Peter, Overend, Philip, Hilpert, Jan, López, Francisco J, Ng, Yin Shan Eric, Coffey, Pete, Jeffery, Glen

“…Age-related macular degeneration (AMD) is a leading cause of legal blindness in the Western world. There are effective treatments for the vascular…”
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Vitamin D rejuvenates aging eyes by reducing inflammation, clearing amyloid beta and improving visual function by Lee, Vivian, Rekhi, Elissa, Hoh Kam, Jaimie, Jeffery, Glen

“…Abstract Vitamin D3 plays a key role in immune regulation and may protect against the aging process. A focal point for age-related changes is the outer retina…”
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Mitochondria are specifically vulnerable to 420nm light in drosophila which undermines their function and is associated with reduced fly mobility by Kam, Jaimie Hoh, Hogg, Chris, Fosbury, Robert, Shinhmar, Harpreet, Jeffery, Glen

“…Increased blue light exposure has become a matter of concern as it has a range of detrimental effects, but the mechanisms remain unclear. Mitochondria absorb…”
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Shifting patterns of cellular energy production (adenosine triphosphate) over the day and key timings for the effect of optical manipulation by Shinhmar, Harpreet, Hoh Kam, Jaimie, Mitrofanis, John, Hogg, Chris, Jeffery, Glen

“…Mitochondria are optically responsive organelles producing energy for cell function via adenosine triphosphate (ATP). But ATP production appears to vary over…”
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The eyes of the deep diving hooded seal (Cystophora cristata) enhance sensitivity to ultraviolet light by Hogg, Chris, Neveu, Magella, Folkow, Lars, Stokkan, Karl-Arne, Hoh Kam, Jaimie, Douglas, Ron H, Jeffery, Glen

“…The mammalian visual range is approximately 400-700 nm, although recent evidence suggests varying ultraviolet (UV) extensions in diverse terrestrial species…”
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Complement factor H regulates retinal development and its absence may establish a footprint for age related macular degeneration by Sivapathasuntharam, Chrishne, Hayes, Matthew John, Shinhmar, Harpreet, Kam, Jaimie Hoh, Sivaprasad, Sobha, Jeffery, Glen

“…Age related macular degeneration (AMD) is the most common blinding disease in those over 60 years. In 50% of cases it is associated with polymorphisms of…”
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A day in the life of mitochondria reveals shifting workloads by Weinrich, Tobias W., Kam, Jaimie Hoh, Ferrara, Bill T., Thompson, Elinor P., Mitrofanis, John, Jeffery, Glen

“…Mitochondria provide energy for cellular function. We examine daily changing patterns of mitochondrial function and metabolism in Drosophila in vivo in terms…”
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Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery by Kam, Jaimie Hoh, Shinhmar, Harpreet, Powner, Michael Barry, Hayes, Matthew John, Aboelnour, Asmaa, Jeffery, Glen

“…Mitochondrial decline is a key feature of ageing. The retina has more mitochondria than any other tissue and ages rapidly. To understand human retinal ageing…”
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Biallelic Mutations in PLA2G5, Encoding Group V Phospholipase A2, Cause Benign Fleck Retina by Sergouniotis, Panagiotis I., Davidson, Alice E., Mackay, Donna S., Lenassi, Eva, Li, Zheng, Robson, Anthony G., Yang, Xu, Kam, Jaimie Hoh, Isaacs, Timothy W., Holder, Graham E., Jeffery, Glen, Beck, Jonathan A., Moore, Anthony T., Plagnol, Vincent, Webster, Andrew R.

“…Flecked-retina syndromes, including fundus flavimaculatus, fundus albipunctatus, and benign fleck retina, comprise a group of disorders with widespread or…”
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Fundamental differences in patterns of retinal ageing between primates and mice by Kam, Jaimie Hoh, Weinrich, Tobias W., Shinhmar, Harpreet, Powner, Michael B., Roberts, Nicholas W., Aboelnour, Asmaa, Jeffery, Glen

“…Photoreceptors have high metabolic demands and age rapidly, undermining visual function. We base our understanding mainly on ageing mice where elevated…”
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Aged complement factor H knockout mice kept in a clean barriered environment have reduced retinal pathology by Hoh Kam, Jaimie, Morgan, James E., Jeffery, Glen

“…Age-related macular degeneration (AMD) is the largest cause of visual loss in those over 60 years in the West and is a condition increasing in prevalence. Many…”
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Topical cyclodextrin reduces amyloid beta and inflammation improving retinal function in ageing mice by Hoh Kam, Jaimie, Lynch, Aisling, Begum, Rana, Cunea, Alex, Jeffery, Glen

“…Retinal ageing results in chronic inflammation, extracellular deposition, including that of amyloid beta (Aβ) and declining visual function. In humans this can…”
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Mitochondrial absorption of short wavelength light drives primate blue retinal cones into glycolysis which may increase their pace of aging by Kam, Jaimie Hoh, Weinrich, Tobias W, Sangha, Harpreet, Powner, Michael B, Fosbury, Robert, Jeffery, Glen

“…Photoreceptors have high energy demands and densely packed mitochondria through which light passes before phototransduction. Old world primates including…”
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