Search Results - "Kam, Angel Y.F"

Naltrexone Facilitates Learning and Delays Extinction by Increasing AMPA Receptor Phosphorylation and Membrane Insertion by Kibaly, Cherkaouia, Kam, Angel Y.F, Loh, Horace H, Law, Ping-Yee

“…Abstract Background The opioid antagonists naloxone/naltrexone are involved in improving learning and memory, but their cellular and molecular mechanisms…”
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CCR5 Signaling Promotes Murine and Human Hematopoietic Regeneration following Ionizing Radiation by Piryani, Sadhna O., Kam, Angel Y.F., Vu, Uyen T., Chao, Nelson J., Doan, Phuong L.

“…Hematopoietic stem and progenitor cells (HSPCs) depend on regulatory cytokines from the marrow microenvironment. From an unbiased cytokine screen of murine…”
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Formyl peptide-receptor like-1 requires lipid raft and extracellular signal-regulated protein kinase to activate inhibitor-κB kinase in human U87 astrocytoma cells by Kam, Angel Y.F, Liu, Andrew M.F, Wong, Yung H

“…Formyl peptide-receptor like-1 (FPRL-1) may possess critical roles in Alzheimer's diseases, chemotaxis and release of neurotoxins, possibly through its…”
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Targeting High Mobility Group Box-1 (HMGB1) Promotes Cell Death in Myelodysplastic Syndrome by Kam, Angel Y F, Piryani, Sadhna O, McCall, Chad M, Park, Hee Su, Rizzieri, David A, Doan, Phuong L

“…Myelodysplastic syndrome (MDS) is associated with a dysregulated innate immune system. The purpose of this study was to determine whether modulation of the…”
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Inhibition of High Mobility Group Box-1 (HMGB1) Eradicates Human Myelodysplastic Syndrome by Kam, Angel Y.F., Piryani, Sadhna O., McCall, Chad M., Park, Hee Su, Chao, Nelson J., Doan, Phuong L.

“…Myelodysplastic syndrome (MDS) is a heterogeneous and pre-leukemic clonal stem cell disorder characterized by aberrant hematopoiesis and bone marrow failure…”
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Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury by Piryani, Sadhna O., Jiao, Yiqun, Kam, Angel Y.F., Liu, Yang, Vo-Dinh, Tuan, Chen, Benny J., Chao, Nelson J., Doan, Phuong L.

“…Extracellular vesicles (EVs) are shed vesicles that bear a combination of nucleic acids and proteins. EVs are becoming recognized as a mode of cell-to-cell…”
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Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury by Piryani, Sadhna O., Jiao, Yiqun, Kam, Angel Y.F., Liu, Yang, Vo-Dinh, Tuan, Chen, Benny J., Chao, Nelson J., Doan, Phuong L.

“…Hematopoietic stem cells (HSCs) reside in specialized microenvironments and adjacent to endothelial cells (ECs), from which they receive regulatory cues…”
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Selective ERBB2 and BCL2 Inhibition Is Synergistic for Mitochondrial-Mediated Apoptosis in MDS and AML Cells by Kam, Angel Y F, Piryani, Sadhna O, Lee, Chang-Lung, Rizzieri, David A, Spector, Neil L, Sarantopoulos, Stefanie, Doan, Phuong L

“…The proto-oncogene is associated with an aggressive phenotype in breast cancer. Its role in hematologic malignancies is incompletely defined, in part because…”
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Epidermal growth factor and G-CSF signaling are synergistic for hematopoietic regeneration by Piryani, Sadhna O., Kam, Angel Y.F., Kliassov, Evelyna G., Chen, Benny J., Spector, Neil L., Chute, John P., Hsu, David S., Chao, Nelson J., Doan, Phuong L.

“…Hematopoietic regeneration following chemotherapy may be distinct from regeneration following radiation. While we have shown that epidermal growth factor (EGF)…”
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Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration by Piryani, Sadhna O., Kam, Angel Y. F., Kliassov, Evelyna G., Chen, Benny J., Spector, Neil L., Chute, John P., Hsu, David S., Chao, Nelson J., Doan, Phuong L.

“…Hematopoietic regeneration following chemotherapy may be distinct from regeneration following radiation. While we have shown that epidermal growth factor (EGF)…”
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EGF Accelerates Hematopoietic Stem Cell Regeneration Following 5-FU Chemotherapy Via G-CSF Receptor Signaling by Piryani, Sadhna O., Kam, Angel Y.F., Kliassov, Evelyna G., Chen, Benny J., Spector, Neil L., Chute, John P., Chao, Nelson J., Doan, Phuong L.

“…Hematopoietic stem cells (HSCs) reside in specialized bone marrow microenvironments adjacent to endothelial cells (BM ECs). BM ECs regulate both HSC…”
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Formyl peptide receptor like 1 differentially requires mitogen-activated protein kinases for the induction of glial fibrillary acidic protein and interleukin-1α in human U87 astrocytoma cells by Kam, Angel Y.F., Tse, Timothy T.M., Kwan, Dawna H.T., Wong, Yung H.

“…Mitogen-activated protein kinases (MAPKs) are not only pivotal mediators of signal transduction but they also regulate diverse biological processes ranging…”
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Phosphatidylinositol‐3 kinase is distinctively required for µ‐, but not κ‐opioid receptor‐induced activation of c‐Jun N‐terminal kinase by Kam, Angel Y. F., Chan, Anthony S. L., Wong, Yung H.

“…Opioid receptors are the therapeutic targets of narcotic analgesics. All three types of opioid receptors (µ, δ and κ) are prototypical Gi‐coupled receptors…”
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Kappa-opioid receptor signals through Src and focal adhesion kinase to stimulate c-Jun N-terminal kinases in transfected COS-7 cells and human monocytic THP-1 cells by Kam, Angel Y F, Chan, Anthony S L, Wong, Yung H

“…Opioid peptides exert diverse physiological functions through their cognate receptors. One subtype of the opioid receptors, kappa-opioid receptor, is…”
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Rac and Cdc42‐dependent regulation of c‐Jun N‐terminal kinases by the δ‐opioid receptor by Kam, Angel Y. F., Chan, Anthony S. L., Wong, Yung H.

“…Heptahelical opioid receptors utilize Gi proteins to regulate a multitude of effectors including the classical adenylyl cyclases and the more recently…”
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Regulation of STAT3 by μ-opioid receptors in human neuroblastoma SH-SY5Y cells by Yuen, Jessie W. F, So, Ivy Y. W, Kam, Angel Y. F, Wong, Yung H

“…Heptahelical opioid receptors are implicated in the transcriptional regulation of neuronal development. Here we demonstrated that activation of μ-opioid…”
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