Search Results - "Kaludov, Nikola"

Structurally Mapping the Diverse Phenotype of Adeno-Associated Virus Serotype 4 by GOVINDASAMY, Lakshmanan, PADRON, Eric, MCKENNA, Robert, MUZYCZKA, Nicholas, KALUDOV, Nikola, CHIORINI, John A, AGBANDJE-MCKENNA, Mavis

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Adeno-Associated Virus Serotype 4 (AAV4) and AAV5 Both Require Sialic Acid Binding for Hemagglutination and Efficient Transduction but Differ in Sialic Acid Linkage Specificity by Kaludov, N, Brown, K E, Walters, R W, Zabner, J, Chiorini, J A

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Rho GTPases Modulate Entry of Ebola Virus and Vesicular Stomatitis Virus Pseudotyped Vectors by QUINN, Kathrina, BRINDLEY, Melinda A, FLICK, Ramon, MANDELL, Robert, STAPLIN, William, MAURY, Wendy, CHIORINI, John A, WELLER, Melodie L, KALUDOV, Nikola, KONDRATOWICZ, Andrew, HUNT, Catherine L, SINN, Patrick L, MCCRAY, Paul B, STEIN, Colleen S, DAVIDSON, Beverly L

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Discovery of Novel Liver-Stage Antimalarials through Quantum Similarity by Sullivan, David J, Liu, Yi, Mott, Bryan T, Kaludov, Nikola, Martinov, Martin N

“…Without quantum theory any understanding of molecular interactions is incomplete. In principal, chemistry, and even biology, can be fully derived from…”
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Scalable purification of adeno-associated virus type 2, 4, or 5 using ion-exchange chromatography by Kaludov, Nikola, Handelman, Beverly, Chiorini, John A

“…The availability of high-titer, high-purity, adeno-associated virus type 2 (AAV2) stocks has dramatically increased our understanding of this virus and its…”
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BAAV transcytosis requires an interaction with beta-1-4 linked- glucosamine and gp96 by Di Pasquale, Giovanni, Kaludov, Nikola, Agbandje-McKenna, Mavis, Chiorini, John A

“…Cell surface carbohydrates play an important role in virus entry and intracellular trafficking. Bovine Adeno-Associated Virus (BAAV) uses plasma membrane…”
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Discovery of Potent, Novel Nrf2 Inducers Via Quantum Modeling, Virtual Screening, and In Vitro Experimental Validation by Williamson, Tracy P., Amirahmadi, Sara, Joshi, Gururaj, Kaludov, Nikola K., Martinov, Martin N., Johnson, Delinda A., Johnson, Jeffrey A.

“…Nuclear factor erythroid 2‐related factor 2 (Nrf2) is the master transcription factor of the antioxidant response element pathway, coordinating the induction…”
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Structure of Adeno-Associated Virus Type 4 by PADRON, Eric, BOWMAN, Valorie, AGBANDJE-MCKENNA, Mavis, KALUDOV, Nikola, GOVINDASAMY, Lakshmanan, LEVY, Hazel, NICK, Phillip, MCKENNA, Robert, MUZYCZKA, Nicholas, CHIORINI, John A, BAKER, Timothy S

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Discovery of potent, novel, non-toxic anti-malarial compounds via quantum modelling, virtual screening and in vitro experimental validation by Sullivan, Jr, David J, Kaludov, Nikola, Martinov, Martin N

“…Developing resistance towards existing anti-malarial therapies emphasize the urgent need for new therapeutic options. Additionally, many malaria drugs in use…”
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MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery by Kaludov, N K, Wolffe, A P

“…The pathways for selective transcriptional repression of methylated DNA templates by the methyl-CpG-binding protein MeCP2 have been investigated using a…”
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Validation of an artificial intelligence algorithm applied to a metabolic substrate analysis of urine for detection of urothelial cancer by Kaludov, Nikola, Siddiqui, Mohummad Minhaj, Kates, Max, Tripathi, Hemantkumar, Salma, Amatul Nasir, Lotan, Yair, Steinberg, Gary D.

“…Abstract only e16008 Background: Urine tests such as urine cytology are commonly used for the diagnosis and monitoring of urothelial cancer. These tests are…”
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Cell Cycle-Regulated Binding of Nuclear Proteins to Elements within a Mouse H3.2 Histone Gene by Kaludov, Nikola K., Bowman, Tammy L., Sikorski, Eric M., Hurt, Myra M.

“…The histone gene family in mammals consists of 15-20 genes for each class of nucleosomal histone protein. These genes are classified as either…”
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BAAV Transcytosis Requires an Interaction with [beta]-1-4 Linked- Glucosamine and gp96 by Di Pasquale, Giovanni, Kaludov, Nikola, Agbandje-McKenna, Mavis, Chiorini, John A

“…Cell surface carbohydrates play an important role in virus entry and intracellular trafficking. Bovine Adeno-Associated Virus (BAAV) uses plasma membrane…”
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A Mouse Histone H1 Variant, H1b, Binds Preferentially to a Regulatory Sequence within a Mouse H3.2 Replication-dependent Histone Gene by Kaludov, Nikola K., Pabón-Peña, Lil, Seavy, Margaret, Robinson, Gail, Hurt, Myra M.

“…H1 histones, found in all multicellular eukaryotes, associate with linker DNA between adjacent nucleosomes, presumably to keep the chromatin in a compact,…”
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Discovery of Novel Liver-Stage Antimalarials through Quantum Similarity: e0125593 by Sullivan, David J, Liu, Yi, Mott, Bryan T, Kaludov, Nikola, Martinov, Martin N

“…Without quantum theory any understanding of molecular interactions is incomplete. In principal, chemistry, and even biology, can be fully derived from…”
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Xenopus NF-Y pre-sets chromatin to potentiate p300 and acetylation-responsive transcription from the Xenopus hsp70 promoter in vivo by Li, Qiao, Herrler, Michael, Landsberger, Nicoletta, Kaludov, Nikola, Ogryzko, Vasily V., Nakatani, Yoshihiro, Wolffe, Alan P.

“…We identify Xenopus NF‐Y as a key regulator of acetylation responsiveness for the Xenopus hsp70 promoter within chromatin assembled in Xenopus oocyte nuclei…”
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Production, purification and preliminary X-ray crystallographic studies of adeno-associated virus serotype 4 by Kaludov, Nikola, Padron, Eric, Govindasamy, Lakshmanan, McKenna, Robert, Chiorini, John A, Agbandje-McKenna, Mavis

“…Adeno-associated virus (AAV) serotypes 1 to 5 are currently under development as clinical gene delivery vectors for the treatment of human diseases. However,…”
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A Conserved Element in the Protein-Coding Sequence Is Required for Normal Expression of Replication-Dependent Histone Genes in DevelopingXenopusEmbryos by Ficzycz, Andrew, Kaludov, Nikola K., Lele, Zsolt, Hurt, Myra M., Ovsenek, Nick

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A Conserved Element in the Protein-Coding Sequence Is Required for Normal Expression of Replication-Dependent Histone Genes in Developing XenopusEmbryos by Ficzycz, Andrew, Kaludov, Nikola K., Lele, Zsolt, Hurt, Myra M., Ovsenek, Nick

“…Replication-dependent histone genes in the mouse and Xenopusshare a common regulatory element within the protein-encoding sequence called the CRASα element…”
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Identification of a Second Conserved Element Within the Coding Sequence of a Mouse H3 Histone Gene That Interacts With Nuclear Factors and Is Necessary for Normal Expression by Kaludov, Nikola K., Pabón-Peña, Lil, Hurt, Myra M.

“…Replication-dependent histone genes of all four nucleosomal classes are coordinately up-regulated at the beginning of S phase of the eukaryotic cell cycle. The…”
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