Search Results - "Kalsi, K K"
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Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells
Published in PloS one (05-07-2023)“…Airway diseases can disrupt tight junction proteins, compromising the epithelial barrier and making it more permeable to pathogens. In people with pulmonary…”
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E-cigarette constituents propylene glycol and vegetable glycerin decrease glucose uptake and its metabolism in airway epithelial cells in vitro
Published in American journal of physiology. Lung cellular and molecular physiology (01-12-2020)“…Electronic nicotine delivery systems, or e-cigarettes, utilize a liquid solution that normally contains propylene glycol (PG) and vegetable glycerin (VG) to…”
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Antimicrobial resistance genes in marine bacteria and human uropathogenic Escherichia coli from a region of intensive aquaculture
Published in Environmental microbiology reports (01-10-2015)“…Antimicrobials are heavily used in Chilean salmon aquaculture. We previously found significant differences in antimicrobial‐resistant bacteria between…”
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Dehydration accelerates reductions in cerebral blood flow during prolonged exercise in the heat without compromising brain metabolism
Published in American journal of physiology. Heart and circulatory physiology (01-11-2015)“…Dehydration hastens the decline in cerebral blood flow (CBF) during incremental exercise, whereas the cerebral metabolic rate for O2 (CMRO2 ) is preserved. It…”
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Cognitive stimulation in the workplace, plasma proteins, and risk of dementia: three analyses of population cohort studies
Published in BMJ (Online) (2021)“…To examine the association between cognitively stimulating work and subsequent risk of dementia and to identify protein pathways for this association…”
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Local temperature-sensitive mechanisms are important mediators of limb tissue hyperemia in the heat-stressed human at rest and during small muscle mass exercise
Published in American journal of physiology. Heart and circulatory physiology (15-07-2015)“…Limb tissue and systemic blood flow increases with heat stress, but the underlying mechanisms remain poorly understood. Here, we tested the hypothesis that…”
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Mechanisms for the control of local tissue blood flow during thermal interventions: influence of temperature‐dependent ATP release from human blood and endothelial cells
Published in Experimental physiology (01-02-2017)“…New Findings What is the central question of this study? Skin and muscle blood flow increases with heating and decreases with cooling, but the…”
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Temperature‐dependent release of ATP from human erythrocytes: mechanism for the control of local tissue perfusion
Published in Experimental physiology (01-03-2012)“…Human limb muscle and skin blood flow increases significantly with elevations in temperature, possibly through physiological processes that involve…”
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Carbapenem resistance in Klebsiella pneumoniae not detected by automated susceptibility testing
Published in Emerging infectious diseases (01-08-2006)“…Detecting beta-lactamase-mediated carbapenem resistance among Klebsiella pneumoniae isolates and other Enterobacteriaceae is an emerging problem. In this…”
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Completeness and accuracy of national cancer and death registration for outcome ascertainment in trials-an ovarian cancer exemplar
Published in Current controlled trials in cardiovascular medicine (25-01-2021)“…There is a trend to increasing use of routinely collected health data to ascertain outcome measures in trials. We report on the completeness and accuracy of…”
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OX-HDL: A Starring Role in Cardiorenal Syndrome and the Effects of Heme Oxygenase-1 Intervention
Published in Diagnostics (Basel) (20-11-2020)“…In this review, we will evaluate how high-density lipoprotein (HDL) and the reverse cholesterol transport (RCT) pathway are critical for proper…”
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Association of hysterectomy and invasive epithelial ovarian and tubal cancer: a cohort study within UKCTOCS
Published in BJOG : an international journal of obstetrics and gynaecology (01-01-2022)“…Objective To investigate the association between hysterectomy with conservation of one or both adnexa and ovarian and tubal cancer. Design Prospective cohort…”
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Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3
Published in Human gene therapy (01-12-2010)“…Adeno-associated viruses (AAVs) use a variety of cellular receptors/coreceptors to gain entry into cells. A number of AAV serotypes are now available, and the…”
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Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial
Published in The Lancet (British edition) (05-06-2021)“…Ovarian cancer continues to have a poor prognosis with the majority of women diagnosed with advanced disease. Therefore, we undertook the UK Collaborative…”
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Differential Effects of Itaconate and its Esters on the Glutathione and Glucose Metabolism of Cultured Primary Rat Astrocytes
Published in Neurochemical research (01-02-2025)“…Abstract Itaconate is produced as endogenous metabolite by decarboxylation of the citric acid cycle intermediate cis -aconitate. As itaconate has…”
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Getting sweeter: new evidence for glucose transporters in specific cell types of the airway?
Published in American Journal of Physiology: Cell Physiology (01-01-2023)“…New technologies such as single-cell RNA sequencing (scRNAseq) has enabled identification of the mRNA transcripts expressed by individual cells. This review…”
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Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial
Published in The Lancet (British edition) (05-03-2016)“…Summary Background Ovarian cancer has a poor prognosis, with just 40% of patients surviving 5 years. We designed this trial to establish the effect of early…”
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Pharmacological activators of AMP‐activated protein kinase have different effects on Na+ transport processes across human lung epithelial cells
Published in British journal of pharmacology (01-08-2007)“…Background and purpose: AMP‐activated protein kinase (AMPK) is activated by metformin, phenformin, and the AMP mimetic,…”
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Prevention of Dental trauma
Published in Primary dental journal (01-12-2023)“…Traumatic dental injuries (TDIs) occur commonly in children and young adults with one in three adults having experience of a TDI to their permanent dentition…”
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