Search Results - "Kalpouzos, G"

Why sickness hurts: A central mechanism for pain induced by peripheral inflammation by Karshikoff, B, Jensen, K.B, Kosek, E, Kalpouzos, G, Soop, A, Ingvar, M, Olgart Höglund, C, Lekander, M, Axelsson, J

“…Highlights • Experimental. • inflammation down-regulates the descending inhibitory pain pathway. • Inflammation induces stronger affective and interoceptive…”
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The influence of negative life events on hippocampal and amygdala volumes in old age: a life-course perspective by Gerritsen, L, Kalpouzos, G, Westman, E, Simmons, A, Wahlund, L O, Bäckman, L, Fratiglioni, L, Wang, H X

“…Psychosocial stress has been related to changes in the nervous system, with both adaptive and maladaptive consequences. The aim of this study was to examine…”
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Three-dimensional surface mapping of hippocampal atrophy progression from MCI to AD and over normal aging as assessed using voxel-based morphometry by Chételat, G., Fouquet, M., Kalpouzos, G., Denghien, I., De la Sayette, V., Viader, F., Mézenge, F., Landeau, B., Baron, J.C., Eustache, F., Desgranges, B.

“…The hippocampus is the brain structure of highest and earliest structural alteration in Alzheimer's disease (AD). New developments in neuroimaging methods…”
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Daytime Sleepiness, Apnea, Neuroimaging Correlates and Cortisol Dysregulation in a Memory Clinic Cohort by Sørensen, Charlotte, Kåreholt, I., Kalpouzos, G., Udeh-Momoh, C. T., Holleman, J., Aspö, M., Hagman, G., Spulber, G., Kivipelto, M., Solomon, A., Sindi, S.

“…Background Sleep disturbances as well as cortisol hypersecretion are increasingly acknowledged as risk factors for Alzheimer’s disease (AD). However, the…”
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Do cardiovascular risk factors explain the link between white matter hyperintensities and brain volumes in old age? A population-based study by Wang, R., Fratiglioni, L., Laveskog, A., Kalpouzos, G., Ehrenkrona, C.-H., Zhang, Y., Bronge, L., Wahlund, L.-O., Bäckman, L., Qiu, C.

“…Background and purpose White matter hyperintensities (WMHs) and brain atrophy frequently coexist in older people. However, it is unclear whether the…”
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Working memory and FDG-PET dissociate early and late onset Alzheimer disease patients by KALPOUZOS, Grégoria, EUSTACHE, Francis, DE LA SAYETTE, Vincent, VIADER, Fausto, CHETELAT, Gaël, DESGRANGES, Béatrice

“…The aims of this study were to determine the influence of the onset of Alzheimer's disease (AD) on 1) memory and cerebral glucose metabolism, 2) the…”
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LPS increases pain sensitivity by decreased pain inhibition and increased insular activation by Karshikoff, B, Jensen, K.B, Ingvar, M, Kosek, E, Kalpouzos, G, Soop, A, Höglund, C. Olgart, Lekander, M, Axelsson, J

“…We have shown that women are more prone to developing LPS-induced pain sensitivity than men, and that the descending endogenous pain inhibition is disrupted in…”
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Cerebral imaging in healthy aging: contrast with Alzheimer disease by Desgranges, B, Kalpouzos, G, Eustache, F

“…With age, the brain undergoes both structural and functional alterations. Overall, the literature consistently reports global brain atrophy in normal adults,…”
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Prediabetes and diabetes accelerate cognitive decline and predict microvascular lesions: A population-based cohort study by Marseglia, Anna, Fratiglioni, Laura, Kalpouzos, Grégoria, Wang, Rui, Bäckman, Lars, Xu, Weili

“…The impact of prediabetes and diabetes on cognitive decline and the potential underlying mechanisms remain unclear. We investigated whether prediabetes and…”
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Functional coherence of striatal resting-state networks is modulated by striatal iron content by Salami, Alireza, Avelar-Pereira, Bárbara, Garzón, Benjamín, Sitnikov, Rouslan, Kalpouzos, Grégoria

“…Resting-state spontaneous fluctuations have revealed individual differences in the functional architecture of brain networks. Previous research indicates that…”
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Association of white matter hyperintensity accumulation with domain-specific cognitive decline: a population-based cohort study by Li, Yuanjing, Kalpouzos, Grégoria, Bäckman, Lars, Qiu, Chengxuan, Laukka, Erika J.

“…We investigated the association of load and accumulation of white matter hyperintensities (WMHs) with rate of cognitive decline. This population-based study…”
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Effects of vascular risk factors and APOE ε4 on white matter integrity and cognitive decline by Wang, Rui, Fratiglioni, Laura, Laukka, Erika J, Lövdén, Martin, Kalpouzos, Grégoria, Keller, Lina, Graff, Caroline, Salami, Alireza, Bäckman, Lars, Qiu, Chengxuan

“…OBJECTIVE:To investigate the effects of vascular risk factors and APOE status on white matter microstructure, and subsequent cognitive decline among older…”
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Specific nutrient patterns are associated with higher structural brain integrity in dementia-free older adults by Prinelli, Federica, Fratiglioni, Laura, Kalpouzos, Grégoria, Musicco, Massimo, Adorni, Fulvio, Johansson, Ingegerd, Marseglia, Anna, Xu, Weili

“…Optimal nutrition may play a beneficial role in maintaining a healthy brain. However, the relationship between nutrient intake and brain integrity is largely…”
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Association of Methionine to Homocysteine Status With Brain Magnetic Resonance Imaging Measures and Risk of Dementia by Hooshmand, Babak, Refsum, Helga, Smith, A David, Kalpouzos, Grégoria, Mangialasche, Francesca, von Arnim, Christine A F, Kåreholt, Ingemar, Kivipelto, Miia, Fratiglioni, Laura

“…Impairment of methylation status (ie, methionine to homocysteine ratio) may be a modifiable risk factor for structural brain changes and incident dementia. To…”
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Tooth loss is associated with accelerated cognitive decline and volumetric brain differences: a population-based study by Dintica, Christina S., Rizzuto, Debora, Marseglia, Anna, Kalpouzos, Grégoria, Welmer, Anna-Karin, Wårdh, Inger, Bäckman, Lars, Xu, Weili

“…Tooth loss has been related to cognitive impairment; however, its relation to structural brain differences in humans is unknown. Dementia-free participants…”
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Structure-function associations of successful associative encoding by Becker, Nina, Kalpouzos, Grégoria, Salami, Alireza, Laukka, Erika J., Brehmer, Yvonne

“…Functional magnetic resonance imaging (MRI) studies have demonstrated a critical role of hippocampus and inferior frontal gyrus (IFG) in associative memory…”
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Automated segmentation of midbrain structures with high iron content by Garzón, Benjamín, Sitnikov, Rouslan, Bäckman, Lars, Kalpouzos, Grégoria

“…The substantia nigra (SN), the subthalamic nucleus (STN), and the red nucleus (RN) are midbrain structures of ample interest in many neuroimaging studies,…”
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Lifestyle, biological, and genetic factors related to brain iron accumulation across adulthood by Gustavsson, Jonatan, Ištvánfyová, Zuzana, Papenberg, Goran, Falahati, Farshad, Laukka, Erika J., Lehtisalo, Jenni, Mangialasche, Francesca, Kalpouzos, Grégoria

“…Iron is necessary for many neurobiological mechanisms, but its overaccumulation can be harmful. Factors triggering age-related brain iron accumulation remain…”
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Elevated neuroinflammation contributes to the deleterious impact of iron overload on brain function in aging by Salami, Alireza, Papenberg, Goran, Sitnikov, Rouslan, Laukka, Erika J., Persson, Jonas, Kalpouzos, Grégoria

“…Intracellular iron is essential for many neurobiological mechanisms. However, at high concentrations, iron may induce oxidative stress and inflammation. Brain…”
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Progression of neuroimaging markers of cerebral small vessel disease in older adults: A 6-year follow-up study by Li, Yuanjing, Kalpouzos, Grégoria, Laukka, Erika J, Dekhtyar, Serhiy, Bäckman, Lars, Fratiglioni, Laura, Qiu, Chengxuan

“…We investigated progression and interrelationships of cerebral small vessel disease (cSVD) markers. This population-based cohort study included 325…”
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