Search Results - "Kalogeras, K."

HER2 gene copy number status may influence clinical efficacy to anti-EGFR monoclonal antibodies in metastatic colorectal cancer patients by Martin, V, Landi, L, Molinari, F, Fountzilas, G, Geva, R, Riva, A, Saletti, P, De Dosso, S, Spitale, A, Tejpar, S, Kalogeras, K T, Mazzucchelli, L, Frattini, M, Cappuzzo, F

“…Background: In metastatic colorectal cancer (mCRC), KRAS is the only validated biomarker used to select patients for administration of epidermal growth factor…”
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Evaluation of the association of PIK3CA mutations and PTEN loss with efficacy of trastuzumab therapy in metastatic breast cancer by Razis, E., Bobos, M., Kotoula, V., Eleftheraki, A. G., Kalofonos, H. P., Pavlakis, K., Papakostas, P., Aravantinos, G., Rigakos, G., Efstratiou, I., Petraki, K., Bafaloukos, D., Kostopoulos, I., Pectasides, D., Kalogeras, K. T., Skarlos, D., Fountzilas, G.

“…Trastuzumab (T) is effective in metastatic breast cancer (MBC) with HER2 overexpression and/or amplification, but resistance to T develops in a significant…”
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Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study by Psyrri, A., Kalogeras, K.T., Kronenwett, R., Wirtz, R.M., Batistatou, A., Bournakis, E., Timotheadou, E., Gogas, H., Aravantinos, G., Christodoulou, C., Makatsoris, T., Linardou, H., Pectasides, D., Pavlidis, N., Economopoulos, T., Fountzilas, G.

“…The ubiquitin–proteasome system (UPS) plays a pivotal role in tumorigenesis. Components of the UPS have recently been implicated in breast cancer progression…”
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Prognostic significance of RACGAP1 mRNA expression in high-risk early breast cancer: a study in primary tumors of breast cancer patients participating in a randomized Hellenic Cooperative Oncology Group trial by Pliarchopoulou, K., Kalogeras, K. T., Kronenwett, R., Wirtz, R. M., Eleftheraki, A. G., Batistatou, A., Bobos, M., Soupos, N., Polychronidou, G., Gogas, H., Samantas, E., Christodoulou, C., Makatsoris, T., Pavlidis, N., Pectasides, D., Fountzilas, G.

“…Purpose RACGAP1 is a Rac GTPase-activating protein involved in cell growth regulation, cell transformation and metastasis. The aim of the present study was to…”
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Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer: A Hellenic Cooperative Oncology Group (HeCOG) study by Koutras, A K, Kalogeras, K T, Dimopoulos, M-A, Wirtz, R M, Dafni, U, Briasoulis, E, Pectasides, D, Gogas, H, Christodoulou, C, Aravantinos, G, Zografos, G, Timotheadou, E, Papakostas, P, Linardou, H, Razis, E, Economopoulos, T, Kalofonos, H P, Fountzilas, G

“…The aim of the study was to evaluate the prognostic ability of the transcriptional profiling of the HER family genes in early breast cancer, as well as to…”
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Biomarkers as a guide of medical treatment in cardiovascular diseases by Vavuranakis, M, Kariori, M G, Kalogeras, K I, Vrachatis, D A, Moldovan, C, Tousoulis, D, Stefanadis, C

“…There is increasing interest in utilizing novel markers of cardiovascular disease risk and consequently, there is a need to assess the value of their use. In…”
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Cyclin D1 differential activation and its prognostic impact among advanced breast cancer patients treated with trastuzumab by Mountzios, G., Kotoula, V., Koliou, G.-A., Papadopoulou, K., Lazaridis, G., Christodoulou, C., Pentheroudakis, G., Skondra, M., Koutras, A., Linardou, H., Razis, E., Papakostas, P., Chrisafi, S., Aravantinos, G., Nicolaou, I., Goussia, A., Kalogeras, K.T., Pectasides, D.G., Fountzilas, G.

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Vascular endothelial growth factor polymorphisms and clinical outcome in colorectal cancer patients treated with irinotecan-based chemotherapy and bevacizumab by Koutras, A K, Antonacopoulou, A G, Eleftheraki, A G, Dimitrakopoulos, F-I, Koumarianou, A, Varthalitis, I, Fostira, F, Sgouros, J, Briasoulis, E, Bournakis, E, Bafaloukos, D, Bompolaki, I, Galani, E, Kalogeras, K T, Pectasides, D, Fountzilas, G, Kalofonos, H P

“…The aim of the study was to evaluate the association of vascular endothelial growth factor ( VEGF ) genotypes with treatment efficacy in a randomized trial…”
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Triple-negative phenotype is of adverse prognostic value in patients treated with dose-dense sequential adjuvant chemotherapy: a translational research analysis in the context of a Hellenic Cooperative Oncology Group (HeCOG) randomized phase III trial by Skarlos, P., Christodoulou, C., Kalogeras, K. T., Eleftheraki, A. G., Bobos, M., Batistatou, A., Valavanis, C., Tzaida, O., Timotheadou, E., Kronenwett, R., Wirtz, R. M., Kostopoulos, I., Televantou, D., Koutselini, E., Papaspirou, I., Papadimitriou, C. A., Pectasides, D., Gogas, H., Aravantinos, G., Pavlidis, N., Arapantoni, P., Skarlos, D. V., Fountzilas, G.

“…Purpose It is well recognized that breast cancer is a heterogeneous disease. The purpose of the current study was to classify patients according to the…”
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Combination of osteopontin and activated leukocyte cell adhesion molecule as potent prognostic discriminators in HER2- and ER-negative breast cancer by Ihnen, M, Wirtz, R M, Kalogeras, K T, Milde-Langosch, K, Schmidt, M, Witzel, I, Eleftheraki, A G, Papadimitriou, C, Jänicke, F, Briassoulis, E, Pectasides, D, Rody, A, Fountzilas, G, Müller, V

“…Background: To analyse the discriminative impact of osteopontin (OPN) and activated leukocyte cell adhesion molecule (ALCAM), combined with human epidermal…”
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Cyclin D1, EGFR, and Akt/mTOR pathway: Potential prognostic markers in localized laryngeal squamous cell carcinoma by Dionysopoulos, D., Pavlakis, K., Kotoula, V., Fountzilas, E., Markou, K., Karasmanis, I., Angouridakis, N., Nikolaou, A., Kalogeras, K.T., Fountzilas, G.

“…Introduction EGFR (epidermal growth factor receptor), cyclin D1 and Akt/mTOR pathways are active in head and neck cancer. The aim of this study was to explore…”
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Exercise stimulates interleukin-6 secretion: inhibition by glucocorticoids and correlation with catecholamines by Papanicolaou, D A, Petrides, J S, Tsigos, C, Bina, S, Kalogeras, K T, Wilder, R, Gold, P W, Deuster, P A, Chrousos, G P

“…In experimental animals, stress and catecholamines stimulate endogenous interleukin-6 (IL-6) secretion, whereas glucocorticoids inhibit it. To examine whether…”
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Circadian relationships between interleukin (IL)-6 and hypothalamic-pituitary-adrenal axis hormones : Failure of IL-6 to cause sustained hypercortisolism in patients with early untreated rheumatoid arthritis by CROFFORD, L. J, KALOGERAS, K. T, MASTORAKOS, G, MAGIAKOU, M.-A, WELLS, J, KANIK, K. S, GOLD, P. W, CHROUSOS, G. P, WILDER, R. L

“…Systemic symptoms in rheumatoid arthritis (RA) are mediated, at least in part, by elevated levels of circulating interleukin (IL)-6, and this cytokine is also…”
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A delayed diagnosis of a myxoma; an almost fatal error by Katsi, V, Kalogeras, K, Kallikazaros, I

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6015 POSTER DISCUSSION An International Consortium in Chemo-refractory Metastatic Colorectal Cancer Patients Shows Cetuximab Efficacy in Patients Harboring HER2 Gene Copy Number Gain by Martin, V, Sacconi, A, Landi, L, Riva, A, Saletti, P, Geva, R, Tejpar, S, Kalogeras, K, Frattini, M, Cappuzzo, F

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Exercise-induced activation of the hypothalamic-pituitary-adrenal axis: marked differences in the sensitivity to glucocorticoid suppression by Petrides, J S, Mueller, G P, Kalogeras, K T, Chrousos, G P, Gold, P W, Deuster, P A

“…Treadmill exercise activates the hypothalamic-pituitary-adrenal axis and evokes metabolic responses proportional to exercise intensity and duration. To…”
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Percutaneous coronary intervention versus coronary arterial bypass grafting in patients with left main coronary artery disease and chronic kidney disease: a systematic review and meta-analysis by Gialamas, I, Kalogeras, K, Pantelidis, P, Lysandrou, A, Zakynthinos, G, Lytra, T, Gounaridi, M, Katsarou, O, Roubelakis, A, Oikonomou, E, Siasos, G, Vavouranakis, M

“…Abstract Background Left main coronary artery disease (LMCAD), defined as a stenosis of >50%, is a potentially lethal condition that should be treated…”
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Cerebrospinal fluid oxytocin concentration in schizophrenic patients does not differ from control subjects and is not changed by neuroleptic medication by Glovinsky, D, Kalogeras, K T, Kirch, D G, Suddath, R, Wyatt, R J

“…Cerebrospinal fluid (CSF) oxytocin concentrations in 20 neuroleptic-treated schizophrenic patients, 31 neuroleptic-withdrawn schizophrenic patients, and 15…”
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Long-term follow up after percutaneous PFO closure. Does baseline PFO anatomy affect the long term procedural result and the severity of residual shunt? by Katsianos, E, Oikonomou, E, Kalogeras, K, Manousaki, A, Moldovan, C, Aznaouridis, K, Katsarou, O, Kalantzis, C, Siasos, G, Vavouranakis, E

“…Abstract Background Patent foramen ovale (PFO) has been increasingly identified as a cause for left circulation thromboembolism. The risk is even higher in…”
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The role of cardiopulmonary rehabilitation in the recovery of right ventricular function and right ventricular-pulmonary artery coupling in convalescent COVID-19 patients by Gounaridi, M I, Vontetsianos, A, Chynkiamis, N, Theofilis, P, Anastasiou, A, Tzima, I, Zakynthinos, G, Gialamas, I, Goliopoulou, A, Kalogeras, K, Vavouranakis, M, Koulouris, N, Oikonomou, E, Siasos, G

“…Abstract Introduction Coronavirus disease-19 (COVID-19) is predominantly a respiratory disease, but simultaneous cardiovascular impairment has been documented,…”
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