Search Results - "Kalofonou, Melpomeni"

Lab-on-chip assay of tumour markers and human papilloma virus for cervical cancer detection at the point-of-care by Wormald, Benjamin W., Moser, Nicolas, deSouza, Nandita M., Mantikas, Katerina-Theresa, Malpartida-Cardenas, Kenny, Pennisi, Ivana, Ind, Thomas E. J., Vroobel, Katherine, Kalofonou, Melpomeni, Rodriguez-Manzano, Jesus, Georgiou, Pantelis

“…Cervical cancer affects over half a million people worldwide each year, the majority of whom are in resource-limited settings where cytology screening is not…”
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A novel hotspot specific isothermal amplification method for detection of the common PIK3CA p.H1047R breast cancer mutation by Kalofonou, Melpomeni, Malpartida-Cardenas, Kenny, Alexandrou, George, Rodriguez-Manzano, Jesus, Yu, Ling-Shan, Miscourides, Nicholas, Allsopp, Rebecca, Gleason, Kelly L. T., Goddard, Katie, Fernandez-Garcia, Daniel, Page, Karen, Georgiou, Pantelis, Ali, Simak, Coombes, R. Charles, Shaw, Jacqueline, Toumazou, Christofer

“…Breast cancer (BC) is a common cancer in women worldwide. Despite advances in treatment, up to 30% of women eventually relapse and die of metastatic breast…”
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Recent Electrochemical Advancements for Liquid-Biopsy Nucleic Acid Detection for Point-of-Care Prostate Cancer Diagnostics and Prognostics by Broomfield, Joseph, Kalofonou, Melpomeni, Bevan, Charlotte L, Georgiou, Pantelis

“…Current diagnostic and prognostic tests for prostate cancer require specialised laboratories and have low specificity for prostate cancer detection. As such,…”
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Expression Of Intracellular Components of the NF-κB Alternative Pathway (NF-κB2, RelB, NIK and Bcl3) is Associated With Clinical Outcome of NSCLC Patients by Dimitrakopoulos, Foteinos-Ioannis D., Antonacopoulou, Anna G., Kottorou, Anastasia E., Panagopoulos, Nikolaos, Kalofonou, Fotini, Sampsonas, Fotios, Scopa, Chrisoula, Kalofonou, Melpomeni, Koutras, Angelos, Makatsoris, Thomas, Dougenis, Dimitrios, Papadaki, Helen, Brock, Malcolm, Kalofonos, Haralabos P.

“…A growing number of studies has shed light on the role of the NF-κΒ in non-small-cell lung cancer (NSCLC). To address the significance of major effectors of…”
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Genetic Variations of CD40 and LTβR Genes Are Associated With Increased Susceptibility and Clinical Outcome of Non-Small-Cell Carcinoma Patients by Dimitrakopoulos, Foteinos-Ioannis D, Antonacopoulou, Anna G, Kottorou, Anastasia E, Kalofonou, Melpomeni, Panagopoulos, Nikolaos, Dougenis, Dimitrios, Makatsoris, Thomas, Tzelepi, Vasiliki, Koutras, Angelos, Kalofonos, Haralabos P

“…Immune system-related receptors CD40 (tumor necrosis factor receptor superfamily member 5), BAFFR (tumor necrosis factor receptor superfamily member 13C), and…”
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An ISFET based translinear sensor for DNA methylation detection by Kalofonou, Melpomeni, Georgiou, Pantelis, Ou, Chung-Pei, Toumazou, Christofer

“…This paper presents the concept of using a novel ISFET-based readout circuit for ratiometric detection of DNA methylation, which gives a discrete answer once a…”
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Semiconductor technology for early detection of DNA methylation for cancer: From concept to practice by Kalofonou, Melpomeni, Toumazou, Chris

“…The electrical detection of DNA methylation based biomarkers using semiconductor technology shows great promise for early cancer screening. Presented is the…”
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A low power sub- μW chemical gilbert cell for ISFET differential reaction monitoring by Kalofonou, Melpomeni, Toumazou, Christofer

“…This paper presents a low power current-mode method for monitoring differentially derived changes in pH from ion-sensitive field-effect transistor (ISFET)…”
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Predicting Cancer Drug Response Using an Adapted Deep Neural Network Model by Li, Xiaofan, Kalofonou, Melpomeni

“…Recent advancements in biotechnology have contributed to the concept of precision oncology through the application of machine learning algorithms. The proposed…”
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The Fire Within: NF-κB Involvement in Non-Small Cell Lung Cancer by Dimitrakopoulos, Foteinos-Ioannis D, Kottorou, Anastasia E, Kalofonou, Melpomeni, Kalofonos, Haralabos P

“…Thirty-four years since its discovery, NF-κB remains a transcription factor with great potential for cancer therapy. However, NF-κB-targeted therapies have yet…”
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Classification of nucleic acid amplification on ISFET arrays using spectrogram-based neural networks by Tripathi, Prateek, Gulli, Costanza, Broomfield, Joseph, Alexandrou, George, Kalofonou, Melpomeni, Bevan, Charlotte, Moser, Nicolas, Georgiou, Pantelis

“…The COVID-19 pandemic has highlighted a significant research gap in the field of molecular diagnostics. This has brought forth the need for AI-based edge…”
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A Low Power Sub- \muW Chemical Gilbert Cell for ISFET Differential Reaction Monitoring by Kalofonou, Melpomeni, Toumazou, Christofer

“…This paper presents a low power current-mode method for monitoring differentially derived changes in pH from ion-sensitive field-effect transistor (ISFET)…”
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A Low Power Sub-[Formula Omitted]W Chemical Gilbert Cell for ISFET Differential Reaction Monitoring by Kalofonou, Melpomeni, Toumazou, Christofer

“…This paper presents a low power current-mode method for monitoring differentially derived changes in pH from ion-sensitive field-effect transistor (ISFET)…”
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Detection of Multiple Breast Cancer ESR1 Mutations on an ISFET Based Lab-on-Chip Platform by Alexandrou, George, Moser, Nicolas, Mantikas, Katerina-Theresa, Rodriguez-Manzano, Jesus, Ali, Simak, Coombes, R Charles, Shaw, Jacqui, Georgiou, Pantelis, Toumazou, Christopher, Kalofonou, Melpomeni

“…ESR1 mutations are important biomarkers in metastatic breast cancer. Specifically, p.E380Q and p.Y537S mutations arise in response to hormonal therapies given…”
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An ISFET based analogue ratiometric method for DNA methylation detection by Kalofonou, Melpomeni, Toumazou, Chris

“…This paper presents the concept of a ratiometric approach for DNA methylation detection using the "Methylation Cell" for the indication of epigenetic…”
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A trapped charge compensation scheme for ISFET based translinear circuits by Gantier, Martin, Kalofonou, Melpomeni, Toumazou, Chris

“…A trapped charge compensation scheme for ISFET based translinear circuits is presented, as part of a system for prediction of cancer risk, based on DNA…”
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Adapting ISFETs for Epigenetics: An Overview by Ma, Dora, Rodriguez-Manzano, Jesus, de Mateo Lopez, Sara, Kalofonou, Melpomeni, Georgiou, Pantelis, Toumazou, Christofer

“…This paper gives an overview of how CMOS design methods can be applied to ion-sensitive field effect transistor (ISFETs) for pH-based DNA methylation and miRNA…”
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Association of BAFFR expression in CAFs with overall survival and response to platinum-based chemotherapy in NSCLC by Dimtrakopoulos, Fotinos-Ioannis D., Kottorou, Anastasia E, Antonacopoulou, Anna G, Nikolakopoulos, Achilleas, Panagopoulos, Nikolaos, Kalofonou, Melpomeni, Dougenis, Dimitrios, Koutras, Angelos, Makatsoris, Thomas, Tzelepi, Vasiliki, Kalofonos, Haralabos

“…Abstract only 8537 Background: Β-cell activating factor receptor (BAFFR) is a surface receptor, which leads to activation of the Nuclear Factor-kappaB (NF-κB)…”
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Distinguishing PIK3CA p.E545K Mutational Status from Pseudogene DNA with a Next-Generation ISFET Sensor Array by Alexandrou, George, Moser, Nicolas, Ali, Simak, Coombes, Charles, Shaw, Jacqui, Georgiou, Pantelis, Toumazou, Chris, Kalofonou, Melpomeni

“…PIK3CA p.E545K mutation is a well-studied breast cancer biomarker with a clinical significance as a therapeutic target, particularly with the use of the small…”
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The Evolution of Affordable Technologies in Liquid Biopsy Diagnostics: The Key to Clinical Implementation by Alexandrou, George, Mantikas, Katerina-Theresa, Allsopp, Rebecca, Yapeter, Calista Adele, Jahin, Myesha, Melnick, Taryn, Ali, Simak, Coombes, R Charles, Toumazou, Christofer, Shaw, Jacqueline A, Kalofonou, Melpomeni

“…Cancer remains a leading cause of death worldwide, despite many advances in diagnosis and treatment. Precision medicine has been a key area of focus, with…”
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