Search Results - "Kallisch, Heike"

Cloning and Characterization of the 5′-Flanking Region of the Human Cardiotrophin-1 Gene by Erdmann, Jeanette, Hassfeld, Sabine, Kallisch, Heike, Fleck, Eckart, Regitz-Zagrosek, Vera

“…To enable the analysis of the regulation of the human cardiotrophin-1 gene expression, the 5′-flanking region of the human cardiotrophin-1 gene was cloned and…”
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Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-β1 involves furin-convertase by Stawowy, Philipp, Margeta, Christian, Kallisch, Heike, Seidah, Nabil G, Chrétien, Michel, Fleck, Eckart, Graf, Kristof

“…Abstract Objective: Heart failure is characterized by an imbalance of matrix synthesis/turnover, finally resulting in fibrosis. Cardiac myocytes and…”
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Proprotein convertases regulate insulin-like growth factor 1-induced membrane-type 1 matrix metalloproteinase in VSMCs via endoproteolytic activation of the insulin-like growth factor-1 receptor by Stawowy, Philipp, Kallisch, Heike, Kilimnik, Adam, Margeta, Christian, Seidah, Nabil G., Chrétien, Michel, Fleck, Eckart, Graf, Kristof

“…The IGF-1 receptor (IGF-1R) and MT1-MMP are synthesized as larger precursor proproteins, which require endoproteolytic activation by the proprotein convertases…”
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Endoproteolytic activation of αv integrin by proprotein convertase PC5 is required for vascular smooth muscle cell adhesion to vitronectin and integrin-dependent signaling by STAWOWY, Philipp, KALLISCH, Heike, VEINOT, John P, KILIMNIK, Adam, PRICHETT, Wendy, GOETZE, Stephan, SEIDAH, Nabil G, CHRETIEN, Michel, FLECK, Eckart, GRAF, Kristof

“…Background— Integrins play an important role for vascular smooth muscle cell (VSMC) migration during the development of atherosclerosis and restenosis…”
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Endoproteolytic activation of alpha(v) integrin by proprotein convertase PC5 is required for vascular smooth muscle cell adhesion to vitronectin and integrin-dependent signaling by Stawowy, Philipp, Kallisch, Heike, Veinot, John P, Kilimnik, Adam, Prichett, Wendy, Goetze, Stephan, Seidah, Nabil G, Chrétien, Michel, Fleck, Eckart, Graf, Kristof

“…Integrins play an important role for vascular smooth muscle cell (VSMC) migration during the development of atherosclerosis and restenosis. Integrin…”
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Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-beta1 involves furin-convertase by Stawowy, Philipp, Margeta, Christian, Kallisch, Heike, Seidah, Nabil G, Chrétien, Michel, Fleck, Eckart, Graf, Kristof

“…Heart failure is characterized by an imbalance of matrix synthesis/turnover, finally resulting in fibrosis. Cardiac myocytes and fibroblasts play a pivotal…”
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Immunohistochemical localization of subtilisin/kexin-like proprotein convertases in human atherosclerosis by STAWOWY, Philipp, KALLISCH, Heike, BORGES PEREIRA STAWOWY, Nubia, STIBENZ, Dietger, VEINOT, John P, GRÄFE, Michael, SEIDAH, Nabil G, CHRETIEN, Michel, FLECK, Eckart, GRAF, Kristof

“…Integrins are heterodimeric alpha/beta receptors that link the cytoskeleton with the extracellular matrix, thereby regulating several cell functions important…”
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Proprotein convertase PC5 regulation by PDGF-BB involves PI3-kinase/p70(s6)-kinase activation in vascular smooth muscle cells by Stawowy, Philipp, Blaschke, Florian, Kilimnik, Adam, Goetze, Stephan, Kallisch, Heike, Chrétien, Michel, Marcinkiewicz, Mieczyslaw, Fleck, Eckart, Graf, Kristof

“…We have recently demonstrated that furin, PC5, and PC7, members of the subtilisin/kexin-like mammalian proprotein convertases (PCs), are found in rodent aorta…”
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Proprotein Convertase PC5 Regulation by PDGF-BB Involves PI3-Kinase/p70 s6 -Kinase Activation in Vascular Smooth Muscle Cells by Stawowy, Philipp, Blaschke, Florian, Kilimnik, Adam, Goetze, Stephan, Kallisch, Heike, Chrétien, Michel, Marcinkiewicz, Mieczyslaw, Fleck, Eckart, Graf, Kristof

“…We have recently demonstrated that furin, PC5, and PC7, members of the subtilisin/kexin-like mammalian proprotein convertases (PCs), are found in rodent aorta…”
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Proprotein Convertase PC5 Regulation by PDGF-BB Involves PI3-Kinase/p70s6-Kinase Activation in Vascular Smooth Muscle Cells by Stawowy, Philipp, Blaschke, Florian, Kilimnik, Adam, Goetze, Stephan, Kallisch, Heike, Chrétien, Michel, Marcinkiewicz, Mieczyslaw, Fleck, Eckart, Graf, Kristof

“…We have recently demonstrated that furin, PC5, and PC7, members of the subtilisin/kexin-like mammalian proprotein convertases (PCs), are found in rodent aorta…”
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Genetic variants in the promoter (g983G>T) and coding region (A92T) of the human cardiotrophin-1 gene (CTF1) in patients with dilated cardiomyopathy by Erdmann, Jeanette, Hassfeld, Sabine, Kallisch, Heike, Fleck, Eckart, Regitz-Zagrose, Vera

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Five novel genetic variants in the promoter and coding region of the ?B-crystallin gene (CRYAB): -652G>A, -650C>G, -249G>C, S41Y, P51L by Hahner, Axel, Erdmann, Jeanette, Kallisch, Heike, Fleck, Eckart, Regitz-Zagrosek, Vera

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Novel intronic polymorphism (+1675G/A) in the human angiotensin II subtype 2 receptor gene by Erdmann, Jeanette, Guse, Marco, Kallisch, Heike, Fleck, Eckart, Regitz-Zagrosek, Vera

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Five novel genetic variants in the promoter and coding region of the αB-crystallin gene (CRYAB): -652G>A, -650C>G, -249G>C, S41Y, P51L by Hahner, Axel, Erdmann, Jeanette, Kallisch, Heike, Fleck, Eckart, Regitz-Zagrosek, Vera

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Identification of genetic variants (g789C>T and G111S) in the human HSPB2 gene by Hahner, Axel, Erdmann, Jeanette, Kallisch, Heike, Fleck, Eckart, Regitz-Zagrosek, Vera

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Screening the human bradykinin B2 receptor gene in patients with cardiovascular diseases: Identification of a functional mutation in the promoter and a new coding variant (T21M) by Erdmann, Jeanette, Hegemann, Nina, Weidemann, Alexander, Kallisch, Heike, Hummel, Manfred, Hetzer, Roland, Fleck, Eckart, Regitz-Zagrosek, Vera

“…To elucidate if genetic variants in the bradykinin B2 receptor (B2) gene occur that could affect receptor expression and function, we screened for mutations in…”
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