Search Results - "Kallio, Janne P."
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Protodynamic Intracellular Acidification by cis-Urocanic Acid Promotes Apoptosis of Melanoma Cells In Vitro and In Vivo
Published in Journal of investigative dermatology (01-10-2010)“…The extracellular tumor microenvironment is acidified, whereas the intracellular pH of tumor and stromal cells is neutral. cis-Urocanic acid (cis-UCA), an…”
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Growth Differentiation Factor-9 Induces Smad2 Activation and Inhibin B Production in Cultured Human Granulosa-Luteal Cells
Published in The journal of clinical endocrinology and metabolism (01-02-2003)“…The TGFβ family member growth differentiation factor-9 (GDF-9) is an oocyte-derived factor that is essential for mammalian ovarian folliculogenesis. GDF-9…”
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TIMP‐3 promotes apoptosis in nonadherent small cell lung carcinoma cells lacking functional death receptor pathway
Published in International journal of cancer (15-02-2011)“…Tissue inhibitor of metalloproteinases‐3 (TIMP‐3) has previously been identified as a tumor suppressor for adherent malignant and normal cells. TIMP‐3 inhibits…”
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Oncolytic capacity of attenuated replicative semliki forest virus in human melanoma xenografts in severe combined immunodeficient mice
Published in Cancer research (Chicago, Ill.) (15-07-2006)“…Oncolytic viruses have gained attention as a novel form of cancer treatment. Many viral vectors in use today have been rendered safe by deletion of genes…”
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