Search Results - "Kallenberg, Cees G. M."
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Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis
Published in The New England journal of medicine (15-07-2010)“…This multicenter, randomized, double-blind, double-dummy, noninferiority trial compared rituximab with cyclophosphamide for remission induction in…”
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2
Complement Activation Is Involved in Renal Damage in Human Antineutrophil Cytoplasmic Autoantibody Associated Pauci-Immune Vasculitis
Published in Journal of clinical immunology (01-05-2009)“…Objective This study was to investigate the evidence for complement activation in renal biopsy specimens of patients with myeloperoxidase (MPO)-antineutrophil…”
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3
Factors Determining the Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-07-2016)“…Objective Relapse following remission is common in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV), particularly with ANCAs directed at…”
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Increased expression of Toll-like receptors by monocytes and natural killer cells in ANCA-associated vasculitis
Published in PloS one (06-09-2011)“…Toll-like receptors (TLRs) are a family of receptors that sense pathogen associated patterns such as bacterial cell wall proteins. Bacterial infections are…”
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ANCA-associated vasculitides-advances in pathogenesis and treatment
Published in Nature reviews. Rheumatology (01-11-2010)“…ANCA-associated vasculitides (AAV) involve inflammation and fibrinoid necrosis of the vessel wall. This Review highlights advances in our understanding of the…”
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Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays
Published in Proteomics (Weinheim) (01-04-2011)“…Sjögren's syndrome (SS) is a chronic, progressive autoimmune disease primarily affecting women. Diagnosis of SS requires an invasive salivary gland tissue…”
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Using Mass Spectrometry to Quantify Rituximab and Perform Individualized Immunoglobulin Phenotyping in ANCA-Associated Vasculitis
Published in Analytical chemistry (Washington) (21-06-2016)“…Therapeutic monoclonal immunoglobulins (mAbs) are used to treat patients with a wide range of disorders including autoimmune diseases. As pharmaceutical…”
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Differential expression of granulopoiesis related genes in neutrophil subsets distinguished by membrane expression of CD177
Published in PloS one (13-06-2014)“…Differential gene expression in CD177+ and CD177- neutrophils was investigated, in order to detect possible differences in neutrophil function which could be…”
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Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational cohort study
Published in Arthritis research & therapy (01-01-2011)“…Identifying ankylosing spondylitis (AS) patients who are likely to benefit from tumor necrosis factor-alpha (TNF-α) blocking therapy is important, especially…”
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10
Pathogenesis of ANCA-Associated Vasculitis, an Update
Published in Clinical reviews in allergy & immunology (01-10-2011)“…Clinical observations, including a report of neonatal vasculitis occurring in a child born from a mother with anti-neutrophil cytoplasmic antibody directed to…”
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Preclinical validation of salivary biomarkers for primary Sjögren's syndrome
Published in Arthritis care & research (2010) (01-11-2010)“…Objective Sjögren's syndrome (SS) is a systemic autoimmune disease with a variety of presenting symptoms that may delay its diagnosis. We previously discovered…”
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Key advances in the clinical approach to ANCA-associated vasculitis
Published in Nature reviews. Rheumatology (01-08-2014)“…Key Points Aetiology, pathogenesis, pathology and clinical characteristics are the basis of the 2012 Chapel Hill Consensus Conference (CHCC) vasculitis…”
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13
Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis
Published in Annals of the rheumatic diseases (01-08-2013)“…To identify circulating proteins that distinguish between active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission in a…”
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14
Bacterial DNA motifs trigger ANCA production in ANCA-associated vasculitis in remission
Published in Rheumatology (Oxford, England) (01-04-2011)“…CpG motifs, which are highly prevalent in bacterial DNA, have been shown to trigger the production of ANCA in vitro by B lymphocytes from patients with active…”
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Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody–associated vasculitis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2011)“…Objective To identify biomarkers that distinguish between active antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) and remission in a…”
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16
Reactivity against complementary proteinase-3 is not increased in patients with PR3-ANCA-associated vasculitis
Published in PloS one (17-03-2011)“…The etiology of anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitides (AAV) is unknown, but the association between infections and autoimmunity…”
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Decreased CXCR1 and CXCR2 expression on neutrophils in anti-neutrophil cytoplasmic autoantibody-associated vasculitides potentially increases neutrophil adhesion and impairs migration
Published in Arthritis research & therapy (01-01-2011)“…In anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV), persistent inflammation within the vessel wall suggests perturbed neutrophil…”
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Mechanisms of Disease: pathogenesis and treatment of ANCA-associated vasculitides
Published in Nature clinical practice. Rheumatology (01-12-2006)“…Wegener's granulomatosis and microscopic polyangiitis are idiopathic systemic vasculitides strongly associated with antineutrophil cytoplasmic autoantibodies…”
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Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis
Published in Annals of the rheumatic diseases (01-11-2012)“…To develop recommendations for the management of adult and paediatric lupus nephritis (LN). The available evidence was systematically reviewed using the PubMed…”
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Neutrophil membrane expression of proteinase 3 (PR3) is related to relapse in PR3-ANCA-associated vasculitis
Published in Journal of the American Society of Nephrology (01-09-2002)“…Wegener granulomatosis (WG) is strongly associated with the presence of antineutrophil cytoplasm autoantibodies (ANCA) with specificity for proteinase 3 (PR3)…”
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