Search Results - "Kallen, R.G."

Effects of Tityus Serrulatus Scorpion Toxin gamma on Voltage-Gated Na sup + Channels by Marcotte, P, Chen, L.-Q, Kallen, R.G, Chahine, M

“…The effects of Brazilian scorpion Tityus serrulatus toxin gamma (TiTx gamma) were studied on voltage-gated Na sup + channels from human heart (hH1) and rat…”
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Extrapore Residues of the S5-S6 Loop of Domain 2 of the Voltage-Gated Skeletal Muscle Sodium Channel (rSkM1) Contribute to the μ-Conotoxin GIIIA Binding Site by Chahine, M., Sirois, J., Marcotte, P., Chen, L.-Q., Kallen, R.G.

“…The tetradomain voltage-gated sodium channels from rat skeletal muscle (rSkM1) and from human heart (hH1) possess different sensitivities to the 22-amino-acid…”
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Differences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity by Wright, S.N., Wang, S.Y., Kallen, R.G., Wang, G.K.

“…Cocaine and lidocaine are local anesthetics (LAs) that block Na currents in excitable tissues. Cocaine is also a cardiotoxic agent and can induce cardiac…”
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Sea anemone toxin (ATX II) modulation of heart and skeletal muscle sodium channel alpha-subunits expressed in tsA201 cells by Chahine, M, Plante, E, Kallen, R G

“…We have expressed recombinant alpha-subunits of hH1 (human heart subtype 1), rSkM1 (rat skeletal muscle subtype 1) and hSkM1 (human skeletal muscle) sodium…”
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Pore residues critical for mu-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesis by Li, R.A., Tsushima, R.G., Kallen, R.G., Backx, P.H.

“…We have studied mu-conotoxin (mu-CTX) block of rat skeletal muscle sodium channel (rSkM1) currents in which single amino acids within the pore (P-loop) were…”
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Chimeric study of sodium channels from rat skeletal and cardiac muscle by Chen, L.-Q., Chahine, M., Kallen, R.G., Barchi, R.L., Horn, R.

“…Two isoforms of voltage-dependent Na channels, cloned from rat skeletal muscle, were expressed in Xenopus oocytes. The currents of rSkM1 and rSkM2 differ…”
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Genomic organization of the human skeletal muscle sodium channel gene by George, Jr, A L, Iyer, G S, Kleinfield, R, Kallen, R G, Barchi, R L

“…Voltage-dependent sodium channels are essential for normal membrane excitability and contractility in adult skeletal muscle. The gene encoding the principal…”
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Electrophysiological study of chimeric sodium channels from heart and skeletal muscle by Deschênes, I, Chen, L, Kallen, R G, Chahine, M

“…The alpha-subunit cDNAs encoding voltage-sensitive sodium channels of human heart (hH1) and rat skeletal muscle (rSkM1) have been expressed in the tsA201…”
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Lidocaine block of human heart sodium channels expressed in Xenopus oocytes by Chahine, M, Chen, L Q, Barchi, R L, Kallen, R G, Horn, R

“…The tertiary amine lidocaine is used clinically for preventing cardiac arrhythmias, and has been widely studied on mammalian tissue. Xenopus oocytes were used…”
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Expressed Na channel clones differ in their sensitivity to external calcium concentration by Chahine, M., Chen, L.Q., Kallen, R.G., Barchi, R.L., Horn, R.

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RFLP for BgIII at the human skeletal muscle sodium channel locus by EBERS, G. C, HUDSON, A. J, GEORGE, A. L, BARCHI, R. L, KALLEN, R. G

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Substituent effects on amide hydrogen exchange rates in aqueous solution by Molday, Robert S, Kallen, Roland G

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Analysis of a T4 DNA replication protein complex. Studies of the DNA recognition site for T4 gene 44/62 and 45 protein-catalyzed ATP hydrolysis by Piperno, J R, Kallen, R G, Alberta, B M

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