Search Results - "Kall, Morten A"

Development and validation of a selective and sensitive bioanalytical procedure for the quantitative determination of gaboxadol in human plasma employing mixed mode solid phase extraction and hydrophilic interaction liquid chromatography with tandem mass spectroscopic detection by Kall, Morten A., Fu, Irong, Dige, Tina, Vallano, Patrick, Woolf, Eric, Jørgensen, Martin

“…A selective and sensitive hydrophilic interaction liquid chromatography tandem mass spectrometric bioanalytical method for the quantitative determination of…”
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Determination of Vitamin B6 Vitamers and Pyridoxic Acid in Plasma: Development and Evaluation of a High-Performance Liquid Chromatographic Assay by Bisp, Marianne R., Vakur Bor, Mustafa, Heinsvig, Else-Marie, Kall, Morten A., Nexø, Ebba

“…Marginal deficiency of vitamin B6 has recently been related to cardiovascular diseases. Because of that there is an increasing interest in a suitable and…”
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Electrophysiological safety of sertindole in dogs with normal and remodeled hearts by Thomsen, Morten B, Volders, Paul G A, Stengl, Milan, Spätjens, Roel L H M G, Beekman, Jet D M, Bischoff, Ulrike, Kall, Morten A, Frederiksen, Kristen, Matz, Jørgen, Vos, Marc A

“…Inhibition of the potassium current IKr and QT prolongation are associated with drug-induced torsades de pointes arrhythmias (TdP) and sudden cardiac death. We…”
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Tiered Approach Into Practice: Scientific Validation for Chromatography-Based Assays in Early Development – A Recommendation from The European Bioanalysis Forum by Timmerman, Philip, White, Stephen, McDougall, Stuart, Kall, Morten A, Smeraglia, John, Fjording, Marianne Scheel, Knutsson, Magnus

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Quantitative determination of the antidepressant vortioxetine and its major human metabolite in plasma by Kall, Morten A, Rohde, Morten, Jørgensen, Martin

“…Vortioxetine is a novel antidepressant that has been developed in a joint partnership between H. Lundbeck A/S and the Takeda Pharmaceutical Company, Ltd. A…”
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Determination of total vitamin B6 in foods by isocratic HPLC: a comparison with microbiological analysis by Kall, Morten A

“…This paper describes a rapid and sensitive, high performance liquid chromatography (HPLC) method for analysis of vitamin B6 in various foods. The method is…”
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Rectal Absorption of Vigabatrin, a Substrate of the Proton Coupled Amino Acid Transporter (PAT1, Slc36a1), in Rats by Holm, René, Kall, Morten A., Frølund, Sidsel, Nielsen, Andreas L., Jensen, Anne, Broberg, Mie Larsen, Nielsen, Carsten Uhd

“…ABSTRACT Purpose To investigate the rectal absorption of vigabatrin in rats, based on the hypothesis that PAT1 (Slc36a1) is involved. Methods Male…”
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Intestinal Drug Transport via the Proton-Coupled Amino Acid Transporter PAT1 (SLC36A1) Is Inhibited by Gly‑Xaa Dipeptides by Frølund, Sidsel, Langthaler, Louise, Kall, Morten A, Holm, René, Nielsen, Carsten Uhd

“…The oral absorption of some drug substances is mediated by nutrient transporters. As a consequence, nutrients and drugs may compete for available transporters,…”
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Effects of dietary broccoli on human in vivo drug metabolizing enzymes: evaluation of caffeine, oestrone and chlorzoxazone metabolism by Kall, Morten A., Vang, Ole, Clausen, JØrgen

“…Ingestion of cruciferous vegetables may prevent chemically induced carcinogenesis by their influence on specific cytochrome P450 enzymes (CYP) and phase II…”
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Evaluation of an isochronic study design for long-term frozen stability investigation of drugs in biological matrices by Pihl, Susanne, Huusom, Anna Karina Trap, Rohde, Morten, Poulsen, Mette Nøhr, Jørgensen, Martin, Kall, Morten A

“…Long-term stability is a basic parameter in bioanalytical method validation; however, no criteria for conducting long-term stability studies are specified in…”
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Improved method for simultaneous determination of ascorbic acid and dehydroascorbic acid, isoascorbic acid and dehydroisoascorbic acid in food and biological samples by Kall, Morten A, Andersen, Carina

“…The total vitamin C amount in different food and plasma samples was determined by a dual detection system, after HPLC separation, with direct detection of…”
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Optimised extraction of folic acid from multivitamin-mineral preparations for liquid chromatographic analysis by Kall, Morten A, Nørgaard, Pernille, Pedersen, Stig J, Leth, Torben

“…Degradation of folic acid may occur during extraction of multivitamin-mineral preparations. The degradation may be caused by presence of ions such as Fe 3+ and…”
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Determination of total vitamin B 6 in foods by isocratic HPLC: a comparison with microbiological analysis by Kall, Morten A.

“…This paper describes a rapid and sensitive, high performance liquid chromatography (HPLC) method for analysis of vitamin B 6 in various foods. The method is…”
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Intestinal Drug Transport via the Proton-Coupled Amino Acid Transporter PAT1 (SLC36A1) Is Inhibited by Gly-X aa Dipeptides by Frølund, Sidsel, Langthaler, Louise, Kall, Morten A., Holm, René, Nielsen, Carsten Uhd

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Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides by Frølund, Sidsel, Langthaler, Louise, Kall, Morten A, Holm, René, Nielsen, Carsten Uhd

“…The oral absorption of some drug substances is mediated by nutrient transporters. As a consequence, nutrients and drugs may compete for available transporters,…”
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Effects of dietary broccoli on human drug metabolising activity by Kall, Morten A., Vang, Ole, Clausen, Jørgen

“…Eighteen volunteers received 500 g fresh broccoli every day for 12 days after a 6-day period of standard diet. The activity of CYP1A2, CYP2E1 and the estrone 2…”
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