Search Results - "Kalkers, Nynke F"

Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient by Ruiter, Annabel M., Meilof, Jan F., Somanje-Bolweg, Rosemarijn R.J., van Gorsel, Erik, Kalkers, Nynke F.

“…We present the unusual case of a patient with an aquaporin 4 antibody-seropositive neuromyelitis optica spectrum disorder who presented with autonomic…”
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Personalized extended interval dosing of natalizumab in MS: A prospective multicenter trial by van Kempen, Zoé L.E., Hoogervorst, Erwin L.J., Wattjes, Mike P., Kalkers, Nynke F., Mostert, Jop P., Lissenberg-Witte, Birgit I., de Vries, Annick, ten Brinke, Anja, van Oosten, Bob W., Barkhof, Frederik, Teunissen, Charlotte E., Uitdehaag, Bernard M.J., Rispens, Theo, Killestein, Joep

“…OBJECTIVETo determine whether natalizumab efficacy is maintained when switching to personalized extended interval dosing based on individual natalizumab trough…”
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Prospective trial of natalizumab personalised extended interval dosing by therapeutic drug monitoring in relapsing-remitting multiple sclerosis (NEXT-MS) by Toorop, Alyssa A, van Lierop, Zoë YGJ, Gelissen, Liza MY, Hoitsma, Elske, Zeinstra, Esther MPE, van Rooij, Luuk C, van Munster, Caspar EP, Vennegoor, Anke, Mostert, Jop P, Wokke, Beatrijs HA, Kalkers, Nynke F, Hoogervorst, Erwin LJ, van Eijk, Jeroen JJ, Roosendaal, Christiaan M, Kragt, Jolijn J, Eurelings, Marijke, van Genugten, Jessie, Nielsen, Jessica, Sinnige, LGF, Kloosterziel, Mark E, Arnoldus, Edo PJ, van Dijk, Gert W, Bouvy, Willem H, Wessels, Mark HJ, Boonkamp, Lynn, Strijbis, Eva MM, van Oosten, Bob W, De Jong, Brigit A, Lissenberg-Witte, Birgit I, Barkhof, Frederik, Moraal, Bastiaan, Teunissen, Charlotte E, Rispens, Theo, Uitdehaag, Bernard MJ, Killestein, Joep, van Kempen, Zoé LE

“…BackgroundExtended interval dosing (EID) of natalizumab is a promising strategy to optimise treatment in multiple sclerosis (MS). Personalised EID by…”
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Minimal clinically important difference of improvement on the Arm Function in Multiple Sclerosis Questionnaire (AMSQ) by van Munster, Caspar EP, Kaya, Levent, Obura, Morgan, Kalkers, Nynke F, Uitdehaag, Bernard MJ

“…Background: The Arm Function in Multiple Sclerosis Questionnaire (AMSQ) has been developed to assess upper extremity function of patients with multiple…”
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Differential item functioning of the Arm function in Multiple Sclerosis Questionnaire (AMSQ) by language, a study in six countries by Kalkers, Nynke F, Galan, Ingrid, Kerbrat, Anne, Tacchino, Andrea, Kamm, Christian P, O’Connell, Karen, McGuigan, Chris, Edan, Gilles, Montalban, Xavier, Uitdehaag, Bernard MJ, Mokkink, Lidwine B

“…Background: The Arm function in Multiple Sclerosis Questionnaire (AMSQ) has been developed as a self-reported measure of arm and hand functioning for patients…”
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Cognitive impairment and decline in different MS subtypes by Huijbregts, Stephan C.J., Kalkers, Nynke F., de Sonneville, Leo M.J., de Groot, Vincent, Polman, Chris H.

“…This paper presents results of two studies conducted to investigate cognition in different MS subtypes. First, the results of a study that has previously been…”
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Glutamate inhibition in MS: The neuroprotective properties of riluzole by Killestein, Joep, Kalkers, Nynke F., Polman, Chris H.

“…In addition to demyelination and damage to oligodendrocytes, axonal injury and neuronal cell death are dominating histopathological characteristics of multiple…”
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Cytokine producing CD8 + T cells are correlated to MRI features of tissue destruction in MS by Killestein, Joep, Eikelenboom, M.Judith, Izeboud, Thijs, Kalkers, Nynke F., Adèr, Herman J., Barkhof, Frederik, Van Lier, Rene A.W., Uitdehaag, Bernard M.J., Polman, Chris H.

“…Specific T-cell subsets and their ability to produce cytokines have been involved in concepts of multiple sclerosis (MS) pathogenesis. Evidence to link…”
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Expression of adhesion molecules on peripheral lymphocytes predicts future lesion development in MS by Eikelenboom, M. Judith, Killestein, Joep, Izeboud, Thijs, Kalkers, Nynke F., Baars, Paul A., van Lier, Rene A.W., Barkhof, Frederik, Uitdehaag, Bernard M.J., Polman, Chris H.

“…The expression of adhesion molecules (alpha4beta1-integrin, LFA-1, ICAM-1) on T cells, measured by flow cytometry, was compared in different subtypes of…”
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The interleukin-1 gene family in multiple sclerosis susceptibility and disease course by Hooper-van Veen, Tineke, Schrijver, Hans M, Zwiers, Antoon, Crusius, J Bart A, Knol, Dirk L, Kalkers, Nynke F, Laine, Marja L, Barkhof, Frederik, Peña, A Salvador, Polman, Chris H, Uitdehaag, Bernard MJ

“…Multiple sclerosis (MS) is a chronic disease of presumed autoimmune origin with a considerable polygenic influence. We have previously observed that a specific…”
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Longitudinal brain volume measurement in multiple sclerosis: rate of brain atrophy is independent of the disease subtype by Kalkers, Nynke F, Ameziane, Najim, Bot, Joost C J, Minneboo, Arjan, Polman, Chris H, Barkhof, Frederik

“…In multiple sclerosis (MS), brain atrophy depicted by magnetic resonance imaging reflects overall tissue loss, including axonal loss. To determine the course…”
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Serum neurofilament light and glial fibrillary acidic protein levels are not associated with wearing-off symptoms in natalizumab-treated multiple sclerosis patients by Toorop, Alyssa A, Wessels, Mark HJ, Boonkamp, Lynn, Gelissen, Liza MY, Hoitsma, E, Zeinstra, Esther MPE, van Rooij, Luuk C, van Munster, Caspar EP, Vennegoor, Anke, Mostert, Jop P, Wokke, Beatrijs HA, Kalkers, Nynke F, Hoogervorst, Erwin LJ, van Eijk, Jeroen JJ, Roosendaal, Christiaan M, Kragt, Jolijn J, Eurelings, Marijke, van Genugten, Jessie, Nielsen, Jessica, Sinnige, LGF, Kloosterziel, Mark E, Arnoldus, Edo PJ, van Dijk, Gert W, Bouvy, Willem H, Strijbis, Eva MM, van Oosten, Bob W, de Jong, Brigit A, Uitdehaag, Bernard MJ, Rispens, Theo, Killestein, Joep, van Kempen, Zoé LE, Teunissen, Charlotte E

“…Background: Biomarkers of neuronal and axonal damage (serum neurofilament light (sNfL) and serum glial fibrillary acidic protein (sGFAP)) may provide insight…”
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Determinants of cerebral atrophy rate at the time of diagnosis of multiple sclerosis by Jasperse, Bas, Minneboo, Arjan, de Groot, Vincent, Kalkers, Nynke F, van Helden, Paul E, Uitdehaag, Bernard M J, Barkhof, Frederik, Polman, Chris H

“…To identify determinants visible on magnetic resonance imaging of the brain that explain the subsequent rate of cerebral atrophy in patients with recently…”
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Don't be late! Timely identification of cognitive impairment in people with multiple sclerosis: a study protocol by Waskowiak, Pauline T, de Jong, Brigit A, Uitdehaag, Bernard M J, Saddal, Shalina R D, Aarts, Jip, Roovers, Aïda A M, van Oirschot, Pim, de Groot, Vincent, Schaafsma, Frederieke G, van der Hiele, Karin, Ruitenberg, Marit F L, Schoonheim, Menno M, Widdershoven, Guy A M, van der Veen, Sabina, Schippers, Esther C F, Klein, Martin, Hulst, Hanneke E

“…Cognitive impairment occurs in up to 65% of people with multiple sclerosis (PwMS), negatively affecting daily functioning and health-related quality of life…”
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Don't be late! Postponing cognitive decline and preventing early unemployment in people with multiple sclerosis: a study protocol by Aarts, Jip, Saddal, Shalina R D, Bosmans, Judith E, de Groot, Vincent, de Jong, Brigit A, Klein, Martin, Ruitenberg, Marit F L, Schaafsma, Frederieke G, Schippers, Esther C F, Schoonheim, Menno M, Uitdehaag, Bernard M J, van der Veen, Sabina, Waskowiak, Pauline T, Widdershoven, Guy A M, van der Hiele, Karin, Hulst, Hanneke E

“…Up to 65% of people with multiple sclerosis (PwMS) develop cognitive deficits, which hampers their ability to work, participating in day-to-day life and…”
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A study validating changes in the multiple sclerosis functional composite by Hoogervorst, Erwin L J, Kalkers, Nynke F, Uitdehaag, Bernard M J, Polman, Chris H

“…To prospectively characterize the relation between 1-year changes in neurologist ratings of abnormalities as measured by means of the Expanded Disability…”
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Production of IL-1β and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis by de Jong, Brigit A., Huizinga, Tom W.J., Bollen, Eduard L.E.M., Uitdehaag, Bernard M.J., Bosma, Gerlof P.Th, van Buchem, Mark A., Remarque, Edmond J., Burgmans, Alexandra C.S., Kalkers, Nynke F., Polman, Chris H., Westendorp, Rudi G.J.

“…Interleukin-1β (IL-1β) is present in multiple sclerosis (MS) lesions. Interleukin-1 receptor antagonist (IL-1Ra) moderates the induction of experimental…”
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The interleukin-I gene family in multiple sclerosis susceptibility and disease course by HOOPER-VAN VEEN, Tineke, SCHRIJVE, Hans M, UITDEHAAG, Bernard M. J, ZWIERS, Antoon, CRUSIUS, J. Bart A, KNOL, Dirk L, KALKERS, Nynke F, LAINE, Marja L, BARKHOF, Frederik, SALVADOR PENA, A, POLMAN, Chris H

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Production of IL-1beta and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis by de Jong, Brigit A, Huizinga, Tom W J, Bollen, Eduard L E M, Uitdehaag, Bernard M J, Bosma, Gerlof P Th, van Buchem, Mark A, Remarque, Edmond J, Burgmans, Alexandra C S, Kalkers, Nynke F, Polman, Chris H, Westendorp, Rudi G J

“…Interleukin-1beta (IL-1beta) is present in multiple sclerosis (MS) lesions. Interleukin-1 receptor antagonist (IL-1Ra) moderates the induction of experimental…”
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Autonomic Dysregulation, Cognitive Impairment, and Symptoms of Psychosis as an Unusual Presentation in an Anti-Aquaporin 4-Positive Patient by Ruiter, Annabel M, Meilof, Jan F, Somanje-Bolweg, Rosemarijn R J, van Gorsel, Erik, Kalkers, Nynke F

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