Search Results - "Kalkbrenner, Frank"

Effects of a Low-Molecular-Weight CCR-3 Antagonist on Chronic Experimental Asthma by Wegmann, Michael, Goggel, Rolf, Sel, Sarper, Sel, Serdar, Erb, Klaus J, Kalkbrenner, Frank, Renz, Harald, Garn, Holger

“…Eosinophils represent one of the main effector cell populations of allergic airway inflammation and allergic bronchial asthma. Their infiltration correlates…”
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Cloning and functional expression of a human Ca2+-permeable cation channel activated by calcium store depletion by Zitt, C, Zobel, A, Obukhov, A G, Harteneck, C, Kalkbrenner, F, Lückhoff, A, Schultz, G

“…Depletion of intracellular calcium stores generates a signal that activates Ca2+-permeable channels in the plasma membrane. We have identified a human cDNA,…”
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Reduction of a conserved Cys is essential for Myb DNA-binding by Guehmann, Stephan, Vorbrueggen, Gerd, Kalkbrenner, Frank, Moelling, Karin

“…The human c-Myb gene product is a regulator of transcription with intrinsic DNA-binding activity located in two of three aminoterminal repeats R2R3. Three…”
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The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to Gq, Gi and G12 proteins by WITTAU, Norbert, GROSSE, Robert, KALKBRENNER, Frank, GOHLA, Antje, SCHULTZ, Günter, GUDERMANN, Thomas

“…Neuropeptides like galanin produced and released by small cell lung cancer (SCLC) cells are considered principal mitogens in these tumors. We identified the…”
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Cell Cycle-dependent Coupling of the Vasopressin V1a Receptor to Different G Proteins by Abel, Alexander, Wittau, Norbert, Wieland, Thomas, Schultz, Günter, Kalkbrenner, Frank

“…Arginine vasopressin (AVP) regulates biological processes by binding to G protein-coupled receptors. In Swiss 3T3 fibroblasts, expressing the V1a subtype of…”
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Distinct Functions of Gq and G11 Proteins in Coupling α1-Adrenoreceptors to Ca2+ Release and Ca2+ Entry in Rat Portal Vein Myocytes by Macrez-Leprêtre, Nathalie, Kalkbrenner, Frank, Schultz, Günter, Mironneau, Jean

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G Protein Heterotrimer Gα13β1γ3 Couples the Angiotensin AT1A Receptor to Increases in Cytoplasmic Ca2+ in Rat Portal Vein Myocytes by Macrez-Leprêtre, Nathalie, Kalkbrenner, Frank, Morel, Jean-Luc, Schultz, Günter, Mironneau, Jean

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Diversity and selectivity of receptor-G protein interaction by Gudermann, T, Kalkbrenner, F, Schultz, G

“…Cells in a living organism communicate with each other through extracellular molecules such as hormones, neurotransmitters, and growth factors. The majority of…”
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In vitro inhibition and stimulation of purified prostaglandin endoperoxide synthase by flavonoids: structure-activity relationship by Kalkbrenner, F, Wurm, G, von Bruchhausen, F

“…We studied the effects of 37 flavonoids on prostaglandin endoperoxide synthase (EC 1.14.99.1) purified from sheep vesicular glands. Nonplanar flavans were more…”
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Expression of TRPC3 in Chinese Hamster Ovary Cells Results in Calcium-Activated Cation Currents Not Related to Store Depletion by Zitt, Christof, Obukhov, Alexander G., Strübing, Carsten, Zobel, Andrea, Kalkbrenner, Frank, Lückhoff, Andreas, Schultz, Günter

“…TRPC3 (or Htrp3) is a human member of the trp family of Ca2+-permeable cation channels. Since expression of TRPC3 cDNA results in markedly enhanced Ca2+ influx…”
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Sublingual immunotherapy of allergic diseases by Werner-Klein, Melanie, Kalkbrenner, Frank, Erb, Klaus J

“…The only disease-modifying treatment that is available for allergic patients is allergen-specific immunotherapy. Two competing application forms are used:…”
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Transport of protein kinase C alpha into the nucleus requires intact cytoskeleton while the transport of a protein containing a canonical nuclear localization signal does not by Schmalz, D, Kalkbrenner, F, Hucho, F, Buchner, K

“…Protein kinase C undergoes a redistribution from the cytosol into the nucleus upon various stimuli. Since protein kinase C does not contain any known nuclear…”
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A specific Go heterotrimer couples somatostatin receptors to voltage‐gated calcium channels in RINm5F cells by Degtiar, Vadim E., Wittig, Burghardt, Schultz, Günter, Kalkbrenner, Frank

“…The peptide hormone somatostatin inhibits glucose‐induced insulin secretion in the rat insulinoma RINm5F cells by inhibition of voltage‐gated calcium channels…”
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A Heterotrimeric G Protein Complex Couples the Muscarinic m1 Receptor to Phospholipase C-β by Dippel, Edgar, Kalkbrenner, Frank, Wittig, Burghardt, Schultz, Günter

“…We addressed the question as to which subtypes of G protein subunits mediate the activation of phospholipase C-β by the muscarinic m1 receptor. We used the rat…”
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The Drosophila cation channel trpl expressed in insect Sf9 cells is stimulated by agonists of G-protein-coupled receptors by Harteneck, Christian, Obukhov, Alexander G., Zobel, Andrea, Kalkbrenner, Frank, Schultz, Günter

“…Structures and regulations of vertebrate channels responsible for sustained calcium elevations after hormone stimulation are largely unknown. Therefore, the…”
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Specificity of interaction between receptor and G protein: use of antisense techniques to relate G-protein subunits to function by Kalkbrenner, Frank, Dippel, Edgar, Wittig, Burghardt, Schultz, Günter

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The galanin receptor type 2 initiates multiple signaling pathways in small cell lung cancer cells by coupling to Gq, Giand G12proteins by Wittau, Norbert, Grosse, Robert, Kalkbrenner, Frank, Gohla, Antje, Schultz, Gunter, Gudermann, Thomas

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Transcriptional activation by human c-myb and v-myb genes by Kalkbrenner, F, Guehmann, S, Moelling, K

“…The human c-myb proto-oncogene is the cellular progenitor of the viral v-myb oncogene and codes for a 75 kD protein involved in growth regulation and…”
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The carboxyterminus of human c-myb protein stimulates activated transcription in trans by Vorbrueggen, Gerd, Kalkbrenner, Frank, Guehmann, Stephan, Moelling, Karin

“…The cellular c-myb gene encodes a transcription factor composed of a DNA-binding domain, a transactivating domain and a regulatory domain located at its…”
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G12 and G13 alpha-subunits are immunochemically detectable in most membranes of various mammalian cells and tissues by Spicher, K, Kalkbrenner, F, Zobel, A, Harhammer, R, Nürnberg, B, Söling, A, Schultz, G

“…The cDNAs of two putatively pertussis toxin-insensitive G-protein alpha-subunits, alpha 12 and alpha 13, were recently cloned. mRNA analyses based on the…”
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