Search Results - "Kalita, Parismita"
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Aminoacyl-tRNA synthetases: Structure, function, and drug discovery
Published in International journal of biological macromolecules (01-05-2018)“…Aminoacyl-tRNA synthetases (AARSs) are the enzymes that catalyze the aminoacylation reaction by covalently linking an amino acid to its cognate tRNA in the…”
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Genome-wide identification and characterization of eukaryotic protein kinases
Published in Frontiers in bioscience (01-06-2020)“…The tropical liver fluke, is a food-borne parasite responsible for the hepatobiliary disease fascioliasis. The recent completion of genome sequencing by…”
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Computational Protein Design for COVID-19 Research and Emerging Therapeutics
Published in ACS central science (26-04-2023)“…As the world struggles with the ongoing COVID-19 pandemic, unprecedented obstacles have continuously been traversed as new SARS-CoV-2 variants continually…”
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An efficient protocol to enhance recombinant protein expression using ethanol in Escherichia coli
Published in MethodsX (01-01-2015)“…Bacterial cells can be engineered to express non-native genes, resulting in the production of, recombinant proteins, which have various biotechnological and…”
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Draft Genome of the Liver Fluke Fasciola gigantica
Published in ACS omega (19-05-2020)“…Fascioliasis, a neglected foodborne disease caused by liver flukes (genus Fasciola), affects more than 200 million people worldwide. Despite technological…”
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Methodological advances in the design of peptide-based vaccines
Published in Drug discovery today (01-05-2022)“…•Peptide vaccines are economical, safer and more efficient than conventional vaccines.•Genomics, proteomics and immunoinformatics have accelerated peptide…”
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Synergistic Effect of Amyloid‑β and Tau Disrupts Neural Circuits
Published in ACS chemical neuroscience (20-03-2019)“…Alzheimer’s disease (AD) is characterized by the coexistence of amyloid-β (Aβ) plaques and tau-based neurofibrillary tangles. Although studies have shown that…”
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Design of a peptide-based subunit vaccine against novel coronavirus SARS-CoV-2
Published in Microbial pathogenesis (01-08-2020)“…Coronavirus disease 2019 (COVID-19) is an emerging infectious disease that was first reported in Wuhan, China, and has subsequently spread worldwide. In the…”
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Development of multi-epitope driven subunit vaccine against Fasciola gigantica using immunoinformatics approach
Published in International journal of biological macromolecules (01-10-2019)“…Fascioliasis, a serious helminth disease of the livestock population, results from infection with the parasite Fasciola. Despite the alarming increase in drug…”
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Structural insights into natural compounds as inhibitors of Fasciola gigantica thioredoxin glutathione reductase
Published in Journal of cellular biochemistry (01-04-2018)“…Fascioliasis is caused by the helminth parasites of genus Fasciola. Thioredoxin glutathione reductase (TGR) is an important enzyme in parasitic helminths and…”
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Immunoinformatics Protocol to Design Multi-Epitope Subunit Vaccines
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…With the development of scientific technologies, the accessibility of genomic data, computational tools, software, databases, and machine learning, the field…”
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From De Novo Design to Redesign: Harnessing Computational Protein Design for Understanding SARS-CoV‑2 Molecular Mechanisms and Developing Therapeutics
Published in The journal of physical chemistry. B (19-10-2023)“…The continuous emergence of novel SARS-CoV-2 variants and subvariants serves as compelling evidence that COVID-19 is an ongoing concern. The swift,…”
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Biochemical and thermodynamic comparison of the selenocysteine containing and non-containing thioredoxin glutathione reductase of Fasciola gigantica
Published in Biochimica et biophysica acta. General subjects (01-06-2018)“…The thiol-disulfide redox metabolism in platyhelminth parasites depends entirely on a single selenocysteine (Sec) containing flavoenzyme, thioredoxin…”
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Conserved Arg451 residue is critical for maintaining the stability and activity of thioredoxin glutathione reductase
Published in Archives of biochemistry and biophysics (15-10-2019)“…Thioredoxin glutathione reductase (TGR), a potential anthelminthic drug target causes NADPH-dependent transfer of electrons to both thioredoxins and…”
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Cover Feature: Enabling Ultrahigh Surface Area of Covalently‐linked Organic Framework for Boosted CO2 Capture: An Air Liquid Interfacial Plasma as Post‐furnishing Protocol (Chem. Eur. J. 38/2023)
Published in Chemistry : a European journal (06-07-2023)“…The underlying features of the presented work is a newly devised strategic economical post‐furnishing protocol, that is, air–liquid interfacial plasma (ALIP),…”
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Enabling Ultrahigh Surface Area of Covalently-linked Organic Framework for Boosted CO 2 Capture: An Air Liquid Interfacial Plasma as Post-furnishing Protocol
Published in Chemistry : a European journal (06-07-2023)“…The cognitive intent of a highly ordered and robust adsorbent is extremely sensible and, in this context, Covalent Organic Framework (COF) materials have…”
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Functional expression, localization, and biochemical characterization of thioredoxin glutathione reductase from air-breathing magur catfish, Clarias magur
Published in International journal of biological macromolecules (01-03-2023)“…The glutathione (GSH) and thioredoxin (Trx) systems regulate cellular redox homeostasis and maintain antioxidant defense in most eukaryotes. We earlier…”
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