Search Results - "Kalisiak, Ewa"

Variability Analysis of Human Plasma and Cerebral Spinal Fluid Reveals Statistical Significance of Changes in Mass Spectrometry-Based Metabolomics Data by Crews, Bridgit, Wikoff, William R, Patti, Gary J, Woo, Hin-Koon, Kalisiak, Ewa, Heideker, Johanna, Siuzdak, Gary

“…Analytical and biological variability are issues of central importance to human metabolomics studies. Here both types of variation are examined in human plasma…”
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Identification of a New Endogenous Metabolite and the Characterization of Its Protein Interactions through an Immobilization Approach by Kalisiak, Jarosław, Trauger, Sunia A, Kalisiak, Ewa, Morita, Hirotoshi, Fokin, Valery V, Adams, Mike W. W, Sharpless, K. Barry, Siuzdak, Gary

“…The emerging field of global mass-based metabolomics provides a platform for discovering unknown metabolites and their specific biochemical pathways. We report…”
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Novel Multiprotein Complexes Identified in the Hyperthermophilic Archaeon Pyrococcus furiosus by Non-denaturing Fractionation of the Native Proteome by Menon, Angeli Lal, Poole, 2nd, Farris L, Cvetkovic, Aleksandar, Trauger, Sunia A, Kalisiak, Ewa, Scott, Joseph W, Shanmukh, Saratchandra, Praissman, Jeremy, Jenney, Jr, Francis E, Wikoff, William R, Apon, John V, Siuzdak, Gary, Adams, Michael W W

“…Virtually all cellular processes are carried out by dynamic molecular assemblies or multiprotein complexes, the compositions of which are largely undefined…”
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A computational framework for proteome-wide pursuit and prediction of metalloproteins using ICP-MS and MS/MS data by Lancaster, W Andrew, Praissman, Jeremy L, Poole, 2nd, Farris L, Cvetkovic, Aleksandar, Menon, Angeli Lal, Scott, Joseph W, Jenney, Jr, Francis E, Thorgersen, Michael P, Kalisiak, Ewa, Apon, Junefredo V, Trauger, Sunia A, Siuzdak, Gary, Tainer, John A, Adams, Michael W W

“…Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze…”
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Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data by Deguchi, Hiroshi, Banerjee, Yajnavalka, Trauger, Sunia, Siuzdak, Gary, Kalisiak, Ewa, Fernández, José A., Hoang, Linh, Tran, Minerva, Yegneswaran, Subramanian, Elias, Darlene J., Griffin, John H.

“…In many patients with deep vein thrombosis and pulmonary embolism (venous thromboembolism, VTE), biomarkers or genetic risk factors have not been identified…”
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Microbial metalloproteomes are largely uncharacterized by Adams, Michael W. W, Cvetkovic, Aleksandar, Menon, Angeli Lal, Thorgersen, Michael P, Scott, Joseph W, Poole II, Farris L, Jenney Jr, Francis E, Lancaster, W. Andrew, Praissman, Jeremy L, Shanmukh, Saratchandra, Vaccaro, Brian J, Trauger, Sunia A, Kalisiak, Ewa, Apon, Junefredo V, Siuzdak, Gary, Yannone, Steven M, Tainer, John A

“…Metal ion cofactors afford proteins virtually unlimited catalytic potential, enable electron transfer reactions and have a great impact on protein stability…”
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metaXCMS: Second-Order Analysis of Untargeted Metabolomics Data by Tautenhahn, Ralf, Patti, Gary J, Kalisiak, Ewa, Miyamoto, Takashi, Schmidt, Manuela, Lo, Fang Yin, McBee, Joshua, Baliga, Nitin S, Siuzdak, Gary

“…Mass spectrometry-based untargeted metabolomics often results in the observation of hundreds to thousands of features that are differentially regulated between…”
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Meta-analysis of global metabolomic data identifies metabolites associated with life-span extension by Patti, Gary J., Tautenhahn, Ralf, Johannsen, Darcy, Kalisiak, Ewa, Ravussin, Eric, Brüning, Jens C., Dillin, Andrew, Siuzdak, Gary

“…The manipulation of distinct signaling pathways and transcription factors has been shown to influence life span in a cell-non-autonomous manner in…”
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Acylcarnitines Are Novel Anticoagulant Lipids That Target Factor Xa and That Are Reduced in Plasma of Venous Thrombosis Patients Based on Untargeted and Targeted Metabolomics by Deguchi, Hiroshi, Banerjee, Yajnavalka, Siuzdak, Gary, Trauger, Sunia, Kalisiak, Ewa, Fernandez, Jose A., Hoang, Linh, Tran, Minerva, Yegneswaran, Subramanian, Elias, Darlene J, Griffin, John H.

“…Deep vein thrombosis and pulmonary embolism (VTE) are common causes of morbidity and mortality. No genetic or acquired biomarkers or risk factors can be…”
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Warfarin untargeted metabolomics study identifies novel procoagulant ethanolamide plasma lipids by Deguchi, Hiroshi, Elias, Darlene J., Trauger, Sunia, Zhang, Hui‐Min, Kalisiak, Ewa, Siuzdak, Gary, Griffin, John H.

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Cerebrospinal Fluid Proteomics Reveals Potential Pathogenic Changes in the Brains of SIV-Infected Monkeys by Pendyala, Gurudutt, Trauger, Sunia A, Kalisiak, Ewa, Ellis, Ronald J, Siuzdak, Gary, Fox, Howard S

“…The HIV-1-associated neurocognitive disorder occurs in approximately one-third of infected individuals. It has persisted in the current era of antiretroviral…”
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Warfarin Untargeted Metabolomics Study Identifies Novel Procoagulant Ethanolamide Lipids by Deguchi, Hiroshi, Trauger, Sunia, Kalisiak, Ewa, Zhang, Hui-Min, Siuzdak, Gary, Griffin, John H., Elias, Darlene J

“…Abstract 1200 Untargeted metabolomics denotes the profiling of several thousand low molecular weight biochemicals, including lipids, hormones, saccharides,…”
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Structural studies and binding properties of pendant diazacoronands—precursors to macrocyclic compounds of planar chirality by Kalisiak, Jarosław, Kalisiak, Ewa, Jurczak, Janusz

“…Structural studies of pendant diazacoronands having an N-benzoyl, N-acetyl, O-benzyl or O-benzoyl side arm were performed by means of X-ray and…”
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Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis by Facciotti, Marc T, Pang, Wyming L, Lo, Fang-yin, Whitehead, Kenia, Koide, Tie, Masumura, Ken-ichi, Pan, Min, Kaur, Amardeep, Larsen, David J, Reiss, David J, Hoang, Linh, Kalisiak, Ewa, Northen, Trent, Trauger, Sunia A, Siuzdak, Gary, Baliga, Nitin S

“…Rapidly characterizing the operational interrelationships among all genes in a given organism is a critical bottleneck to significantly advancing our…”
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Novel Multiprotein Complexes Identified in the Hyperthermophilic Archaeon Pyrococcus furiosus by Non-denaturing Fractionation of the Native ProteomeS by Menon, Angeli Lal, Poole, Farris L., Cvetkovic, Aleksandar, Trauger, Sunia A., Kalisiak, Ewa, Scott, Joseph W., Shanmukh, Saratchandra, Praissman, Jeremy, Jenney, Francis E., Wikoff, William R., Apon, John V., Siuzdak, Gary, Adams, Michael W.W.

“…Virtually all cellular processes are carried out by dynamic molecular assemblies or multiprotein complexes, the compositions of which are largely undefined…”
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