Search Results - "Kaliraj, Perumal"

Immunopotentiating nano-chitosan as potent vaccine carter for efficacious prophylaxis of filarial antigens by Malathi, Balasubramaniyan, Mona, Santhanam, Thiyagarajan, Devasena, Kaliraj, Perumal

“…Lymphatic filariasis (LF), a morbid vector-borne parasitic infection affects millions in tropical areas. Complete eradication can only be achieved by the…”
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Elucidation of immunological response and its regulatory network by P-TUFT-ALT-2: a promising fusion protein vaccine for human lymphatic filariasis by Paul, Rajkumar, Jaiswal, Sandeep, Mahalakshmi, Natarajan, Kaliraj, Perumal

“…Human lymphatic filariasis, a mosquito-borne neglected tropical parasitic disease, needs an early development of prophylactic agents such as a vaccine for its…”
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Evaluation of rapid blood sample collection in the detection of circulating filarial antigens for epidemiological survey by rWbSXP-1 capture assay by Ansel Vishal, Lawrence, Nazeer, Y, Ravishankaran, Rajendran, Mahalakshmi, Natarajan, Kaliraj, Perumal

“…Lymphatic filariasis is a neglected tropical disease leading to profound disfiguring causing socio economic burden in the tropics. Current diagnosis strategies…”
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Cloning, expression and characterization of Brugia malayi abundant larval protein transcript-2 (BmALT-2) expressed in Pichia pastoris by Paul, Rajkumar, Saha, Gundappa, Selvaraja, Vellayan, Kaliraj, Perumal

“…Besides mass drug administration, successful elimination of human lymphatic filariasis, a mosquito-borne tropical parasitic disease, requires developing other…”
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Immunological evaluation of fusion protein of Brugia malayi abundant larval protein transcript-2 (BmALT-2) and Tuftsin in experimental mice model by Paul, Rajkumar, Ilamaran, Meganathan, Khatri, Vishal, Amdare, Nitin, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Filariasis, a neglected tropical helminth disease needs vaccine besides mass drug administration for its successful eradication. An attempt was made to produce…”
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Impairment of Tetanus-Specific Cellular and Humoral Responses following Tetanus Vaccination in Human Lymphatic Filariasis by NOOKALA, Suba, SRINIVASAN, Sundaram, KALIRAJ, Perumal, RANGARAJAN BADRI NARAYANAN, NUTMAN, Thomas B

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Comparison of immunogenicity, protective efficacy of single and cocktail DNA vaccine of Brugia malayi abundant larval transcript (ALT-2) and thioredoxin peroxidase (TPX) in mice by Anand, Setty Balakrishnan, Murugan, Vadivel, Prabhu, Prince Rajaiah, Anandharaman, Veerabhadran, Reddy, Maryada Venkata Rami, Kaliraj, Perumal

“…Although DNA vaccines have several advantages over conventional vaccines, antibody production and protection are often not adequate, particularly in single…”
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Novel Phage Display-Based Subtractive Screening To Identify Vaccine Candidates of Brugia malayi by GNANASEKAR, Munirathinam, RAO, Kakaturu V. N, HE, Yi-Xun, MISHRA, Pankaj K, NUTMAN, Thomas B, KALIRAJ, Perumal, RAMASWAMY, Kalyanasundaram

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunological characterization of recombinant Wuchereria bancrofti cuticular collagen (COL-4) as putative vaccine candidate for human lymphatic filariasis by Arunkumar, Chakkaravarthy, Pandiaraja, Pandurangan, Prince, P R, Kaliraj, Perumal

“…To elucidate immunoprophylactic potential of recombinant Wuchereria bancrofti (W. bancrofti) cuticular collagen (COL-4) in BALB/c mice and filarial clinical…”
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Immune response studies with Wuchereria bancrofti vespid allergen homologue (WbVAH) in human lymphatic filariasis by Anand, Setty Balakrishnan, Gnanasekar, Munirathinam, Thangadurai, Mani, Prabhu, Prince R, Kaliraj, Perumal, Ramaswamy, Kalyanasundaram

“…A homologue of Brugia malayi venom allergen (BmVAH) was cloned from the infective stages (L3) of Wuchereria bancrofti. Sequence analysis showed 90% sequence…”
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Enhancing encapsulation of filarial antigen Brugia malayi thioredoxin in nano-liposomes: The role of lecithin composition by Balasubramaniyan, Malathi, Vinayagam, Vimalraj, Kizhakedathil, Moni Philip Jacob, Perumal, Kaliraj

“…Lymphatic filariasis is a debilitating infectious disease prevalent in endemic areas, necessitating the development of an effective vaccine for eradication…”
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The Larval Specific Lymphatic Filarial ALT-2: Induction of Protection Using Protein or DNA Vaccination by Ramachandran, Sabarinathan, Kumar, Mishra Pankaj, Rami, Reddy Maryada Venkata, Chinnaiah, Harinath Basker, Nutman, Thomas, Kaliraj, Perumal, McCarthy, James

“…Genes from the infective stage of lymphatic filarial parasites expressed at the time of host invasion have been identified as potential vaccine candidates. By…”
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Immunomodulatory effects of chitosan nanoparticles as vaccine delivery agent against lymphatic filariasis through mucosal immunization by Balasubramaniyan, Malathi, Santhanam, Mona, Vinayagam, Vimalraj, Perumal, Kaliraj

“…Lymphatic filariasis is a parasitic disease caused by nematodes affecting millions of individuals in the tropical region. The complex life cycle of the…”
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Development and Evaluation of a Rapid Flow-Through Immuno Filtration Test Using Recombinant Filarial Antigen for Diagnosis of Brugian and Bancroftian Filariasis by Baskar, Lakshmi Kanthan Vijaya, Srikanth, Tokuluva Ramalingam, Suba, Salahudeen, Mody, Himansu Chirag, Desai, Pradeep Kumar, Kaliraj, Perumal

“…There is an imperative need to develop a rapid antibody test that can be used for diagnosis of clinical cases in travelers and expatriates, primary…”
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Development of Antigen Detection ELISA for the Diagnosis of Brugian and Bancroftian Filariasis Using Antibodies to Recombinant Filarial Antigens Bm-SXP-1 and Wb-SXP-1 by Lalitha, Pattabhiraman, Eswaran, Devarajan, Gnanasekar, Muniratnam, Rao, Kakuturu Venkata Nagaraja, Narayanan, Rangarajan Badri, Scott, Alan, Nutman, Thomas, Kaliraj, Perumal

“…Antibodies specific to recombinant filarial antigens Wb‐SXP‐1 and Bm‐SXP‐1 have been used to develop a sandwich ELISA for the detection of circulating filarial…”
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Cloning, large-scale production and characterization of fusion protein (P-TUFT-ALT-2) of Brugian abundant larval transcript-2 with tuftsin in Pichia pastoris by Paul, Rajkumar, Karthik, Selvarajan, Vimalraj, Ponnusamy, Meenakshisundaram, Sankaranarayanan, Kaliraj, Perumal

“…Lymphatic filariasis is a "disease of poor people" due to a large section of affected people with economic backwardness. Therefore, successful elimination of…”
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Enhancing Tuberculosis Treatment Adherence: Evaluating the Efficacy of the Support for Treatment Adherence and Medication Protocols (STAMP) Device for Automatic Dispensing and Real-Time Medication Monitoring by Jason Charles, Simon Chandramohan, Anusha, Krishna, Mahesh, Krishna, Ramasubramanian, Ramachandran, Kaliraj, Perumal, Selvaraj, Vimalraj

“…Tuberculosis (TB) remains a significant global health challenge, necessitating strict adherence to medication for successful treatment and prevention of drug…”
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Immunomodulation of ALT-2 and TLR may collude in antigen specific T cell hyporesponsiveness: Proposed mechanism for elevated IL-10 levels in Balb/C mice by Aparnaa, Ramanathan, Kaliraj, Perumal

“…ALT-2, a novel antigen belonging to the chromadorea ALT-2 family of the filarial nematode is proved to clear filarial parasites in Jirds. In order to increase…”
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Wucherria bancrofti glutathione S-Transferase: Insights into the 2.3 Å resolution X-ray structure and function, a therapeutic target for human lymphatic filariasis by Rajaiah Prabhu, Prince, Moorthy, Sakthi Devi, Madhumathi, Jayaprakasam, Pradhan, Satya Narayan, Perbandt, Markus, Betzel, Christian, Kaliraj, Perumal

“…The notoriety of parasitic nematode survival is directly related to chronic pathogenicity, which is evident in human lymphatic filariasis. It is a disease of…”
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Biodegradable poly-l-lactide based microparticles as controlled release delivery system for filarial vaccine candidate antigens by Anugraha, Gandhirajan, Madhumathi, Jayaprakasam, Jeya Prita, Parasurama Jawaharlal, Kaliraj, Perumal

“…Modern recombinant vaccines are less immunogenic than conventional vaccines which require adjuvants to enhance the effect of a vaccine. Alum is being used as a…”
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