Search Results - "Kalinowska, Magdalena"
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Quantitative profiling of brain lipid raft proteome in a mouse model of fragile X syndrome
Published in PloS one (07-04-2015)“…Fragile X Syndrome, a leading cause of inherited intellectual disability and autism, arises from transcriptional silencing of the FMR1 gene encoding an…”
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Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation
Published in Blood (14-01-2010)“…HIV infection is associated with an increased risk of thrombosis; and as antiretroviral therapy has increased the lifespan of HIV-infected patients, their risk…”
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Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis
Published in Cell reports (Cambridge) (13-04-2021)“…Transcriptional silencing of the FMR1 gene in fragile X syndrome (FXS) leads to the loss of the RNA-binding protein FMRP. In addition to regulating mRNA…”
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Group I Metabotropic Glutamate Receptor Interacting Proteins: Fine-Tuning Receptor Functions in Health and Disease
Published in Current neuropharmacology (01-07-2016)“…Group I metabotropic glutamate receptors mediate slow excitatory neurotransmission in the central nervous system and are critical to activity-dependent…”
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Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndrome
Published in Molecular autism (29-06-2022)“…Fragile X syndrome (FXS), the most common genetic cause of autism spectrum disorder and intellectual disability, is caused by the lack of fragile X mental…”
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Effects of maraviroc and efavirenz on markers of immune activation and inflammation and associations with CD4+ cell rises in HIV-infected patients
Published in PloS one (06-10-2010)“…Maraviroc treatment for HIV-1 infected patients results in larger CD4(+) T cell rises than are attributable to its antiviral activity alone. We investigated…”
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Curcumin induces caspase-3-dependent apoptotic pathway but inhibits DNA fragmentation factor 40/caspase-activated DNase endonuclease in human Jurkat cells
Published in Molecular cancer therapeutics (01-04-2006)“…Curcumin is a natural pigment that has been shown to induce cell death in many cancer cells; however, the death mode depends on the cell type and curcumin…”
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Genetic 3′UTR variations and clinical factors significantly contribute to survival prediction and clinical response in breast cancer patients
Published in Scientific reports (31-03-2020)“…The study describes a relationship between the 3′UTR variants, clinicopathological parameters and response to chemotherapy. We analyzed 33 germline…”
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Bacterial colonization and beta defensins in the female genital tract in HIV infection
Published in Current HIV research (01-09-2012)“…Beta defensins are antimicrobial peptides that serve to protect the host from microbial invasion at skin and mucosal surfaces. Here we explore the…”
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Stabilization of Spine Synaptopodin by mGluR1 Is Required for mGluR-LTD
Published in The Journal of neuroscience (02-03-2022)“…Dendritic spines, actin-rich protrusions forming the postsynaptic sites of excitatory synapses, undergo activity-dependent molecular and structural remodeling…”
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NF‐κB signaling pathway is inhibited by heat shock independently of active transcription factor HSF1 and increased levels of inducible heat shock proteins
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-12-2011)“…NF‐κB transcription factor regulates numerous genes important for inflammation, immune responses and cell survival. HSF1 is the primary transcription factor…”
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Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium - application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data
Published in Proteomics (Weinheim) (01-06-2016)“…Intra‐tumor heterogeneity is a vivid problem of molecular oncology that could be addressed by imaging mass spectrometry. Here we aimed to assess molecular…”
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Increased Platelet and Microparticle Activation in HIV Infection: Upregulation of P-Selectin and Tissue Factor Expression
Published in Journal of acquired immune deficiency syndromes (1999) (01-04-2012)“…OBJECTIVE:HIV-1–infected patients have an increased risk for atherothrombosis and cardiovascular disease, but the mechanism behind these risks is poorly…”
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Actinin-4 Governs Dendritic Spine Dynamics and Promotes Their Remodeling by Metabotropic Glutamate Receptors
Published in The Journal of biological chemistry (26-06-2015)“…Dendritic spines are dynamic, actin-rich protrusions in neurons that undergo remodeling during neuronal development and activity-dependent plasticity within…”
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Recycled interleukin-7 can be delivered to neighboring T cells
Published in The Journal of immunology (1950) (13-04-2015)“…Interleukin-7 (IL-7) is a key homeostatic cytokine that provides signals for T cell survival and proliferation in vivo . Here, we provide evidence that IL-7…”
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Recycled IL-7 Can Be Delivered to Neighboring T Cells
Published in The Journal of immunology (1950) (15-05-2015)“…IL-7 is a key homeostatic cytokine that provides signals for T cell survival and proliferation in vivo. In this article, we provide evidence that IL-7…”
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Interleukin-7 Receptor Signaling Is Deficient in CD4+ T Cells from HIV-Infected Persons and Is Inversely Associated with Aging
Published in The Journal of infectious diseases (01-04-2009)“…Loss of interleukin-7 (IL-2) receptor expression has been described in T lymphocytes from persons with human immunodeficiency virus (HIV) infection,…”
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Metabotropic regulation of dendritic spine structural plasticity
Published 01-01-2015“…Synaptic plasticity is often accompanied by morphological alterations of dendritic spines, small protrusions formed on neuronal dendritic shafts and sites of…”
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Interleukin-7 Receptor Signaling Is Deficient in CD4 super(+) T Cells from HIV-Infected Persons and Is Inversely Associated with Aging
Published in The Journal of infectious diseases (01-04-2009)“…Loss of interleukin-7 (IL-2) receptor expression has been described in T lymphocytes from persons with human immunodeficiency virus (HIV) infection,…”
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