Search Results - "Kalidhindi, Rama Satyanarayana Raju"
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Role of Differential Estrogen Receptor Activation in Airway Hyperreactivity and Remodeling in a Murine Model of Asthma
Published in American journal of respiratory cell and molecular biology (01-10-2019)“…Evidence suggests that airway hyperresponsiveness (AHR) is a characteristic feature of asthma. Epidemiological studies have confirmed that the severity of…”
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2
Estrogen receptor beta signaling inhibits PDGF induced human airway smooth muscle proliferation
Published in Molecular and cellular endocrinology (15-11-2018)“…Airway smooth muscle (ASM) cell hyperplasia driven by persistent inflammation is a hallmark feature of remodeling in asthma. Sex steroid signaling in the lungs…”
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Role of Estrogen Receptors α and β in a Murine Model of Asthma: Exacerbated Airway Hyperresponsiveness and Remodeling in ERβ Knockout Mice
Published in Frontiers in pharmacology (04-02-2020)“…Epidemiological data suggests increased prevalence of asthma in females than males, suggesting a plausible role for sex-steroids, especially estrogen in the…”
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4
Androgen Receptor-Mediated Regulation of Intracellular Calcium in Human Airway Smooth Muscle Cells
Published in Cellular physiology and biochemistry (2019)“…With the prevalence of asthma being greater in women, detrimental effects of female sex steroids have been explored, but potential protective effects of…”
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5
Kisspeptins inhibit human airway smooth muscle proliferation
Published in JCI insight (23-05-2022)“…Sex and gender disparity in asthma is recognized and suggests a modulatory role for sex steroids, particularly estrogen. However, there is a dichotomous role…”
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6
Determination of Histamine H3-Receptor Antagonist Conessine in Wistar Rat Plasma by a Rapid and Sensitive RP-UFLC Method: Application to a Pharmacokinetic Study
Published in Journal of young pharmacists (30-04-2020)“…Objectives: Epidemiological data suggests the highest density of histamine H3-receptors (H3R) in basal ganglia of central nervous system (CNS) wherein they…”
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Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections
Published in Journal of clinical medicine (31-01-2022)“…We previously reported higher ACE2 levels in smokers and patients with COPD. The current study investigates if patients with interstitial lung diseases (ILDs)…”
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Salicylic acid derivatives as potential anti asthmatic agents using disease responsive drug delivery system for prophylactic therapy of allergic asthma
Published in Medical hypotheses (01-02-2016)“…Abstract Asthma is a multi-factorial and complicated lung disorder of the immune system which has expanded to a wider ambit unveiling its etiology to be…”
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9
Brain Targeting of 1,9-Pyrazoloanthrone an c-Jun-N-terminal Kinase Inhibitor Using Liposomes for Effective Management of Parkinson's Disease
Published in Iranian journal of pharmaceutical research : IJPR (01-01-2017)“…The major challenge to treat Parkinson's disease (PD) is penetration of target molecule into the brain to improve the efficacy of drugs. To achieve better…”
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10
Curcumin loaded chitosan nanoparticles impregnated into collagen-alginate scaffolds for diabetic wound healing
Published in International journal of biological macromolecules (01-12-2016)“…Diabetic wounds are a common complication in patients with diabetes that often lead to amputation. Although the pathophysiology of diabetic wound is…”
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11
Sex-Steroid Signaling in Lung Diseases and Inflammation
Published in Advances in experimental medicine and biology (01-01-2021)“…Sex/gender difference exists in the physiology of multiple organs. Recent epidemiological reports suggest the influence of sex-steroids in modulating a wide…”
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12
Cellular and Biochemical Analysis of Bronchoalveolar Lavage Fluid from Murine Lungs
Published in Methods in molecular biology (Clifton, N.J.) (2021)“…Bronchoalveolar lavage (BAL) is a technique used to collect the contents of the airways. The fluid recovered, called BAL fluid (BALF), serves as a dynamic tool…”
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13
Sex steroids skew ACE2 expression in human airway: a contributing factor to sex differences in COVID-19?
Published in American journal of physiology. Lung cellular and molecular physiology (01-11-2020)“…The incidence, severity, and mortality of ongoing coronavirus infectious disease 19 (COVID-19) is greater in men compared with women, but the underlying…”
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14
Androgen receptor activation alleviates airway hyperresponsiveness, inflammation, and remodeling in a murine model of asthma
Published in American journal of physiology. Lung cellular and molecular physiology (01-05-2021)“…Epidemiological studies demonstrate an apparent sex-based difference in the prevalence of asthma, with a higher risk in boys than girls, which is reversed…”
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15
Differential estrogen‐receptor activation regulates extracellular matrix deposition in human airway smooth muscle remodeling via NF‐κB pathway
Published in The FASEB journal (01-12-2019)“…Altered airway smooth muscle (ASM) mass and extracellular matrix (ECM) deposition in airways are characteristic features of remodeling in asthma. Increased ECM…”
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16
Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation
Published in Journal of allergy and clinical immunology (01-04-2024)“…[Display omitted] Serum amyloid A (SAA) is bound to high-density lipoproteins (HDL) in blood. Although SAA is increased in the blood of patients with asthma,…”
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17
Pharmacokinetic and tissue distribution studies of 1,9-pyrazoloanthrone, a c-Jun-N-terminal kinase inhibitor in Wistar rats by a simple and sensitive HPLC method
Published in Journal of pharmaceutical and biomedical analysis (20-02-2016)“…[Display omitted] •The HPLC method was developed and validated.•This method was successfully applied to pharmacokinetic and tissue distribution study in Wistar…”
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