Search Results - "Kalichuk, Valentina"
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Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
Published in Nature methods (01-01-2021)“…Nanobodies are popular and versatile tools for structural biology. They have a compact single immunoglobulin domain organization, bind target proteins with…”
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Allosteric nanobodies to study the interactions between SOS1 and RAS
Published in Nature communications (23-07-2024)“…Protein-protein interactions (PPIs) are central in cell metabolism but research tools for the structural and functional characterization of these PPIs are…”
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Targeted radionuclide therapy with astatine-211: Oxidative dehalogenation of astatobenzoate conjugates
Published in Scientific reports (31-05-2017)“…211 At is a most promising radionuclide for targeted alpha therapy. However, its limited availability and poorly known basic chemistry hamper its use. Based on…”
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The archaeal “7 kDa DNA-binding” proteins: extended characterization of an old gifted family
Published in Scientific reports (17-11-2016)“…The “7 kDa DNA-binding” family, also known as the Sul7d family, is composed of chromatin proteins from the Sulfolobales archaeal order. Among them, Sac7d and…”
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A biosensor-based phage display selection method for automated, high-throughput Nanobody discovery
Published in Biosensors & bioelectronics (01-11-2024)Get full text
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A Single Point Mutation Converts GH84 O‑GlcNAc Hydrolases into Phosphorylases: Experimental and Theoretical Evidence
Published in Journal of the American Chemical Society (05-02-2020)“…Glycoside hydrolases and phosphorylases are two major classes of enzymes responsible for the cleavage of glycosidic bonds. Here we show that two GH84…”
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Affitins: Ribosome Display for Selection of Aho7c-Based Affinity Proteins
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2020)“…Engineered protein scaffolds have made a tremendous contribution to the panel of affinity tools owing to their favorable biophysical properties that make them…”
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A novel, smaller scaffold for Affitins: Showcase with binders specific for EpCAM
Published in Biotechnology and bioengineering (01-02-2018)“…Affitins are highly stable engineered affinity proteins, originally derived from Sac7d and Sso7d, two 7 kDa DNA‐binding polypeptides from Sulfolobus genera…”
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The archaeal "7kDa DNA-binding" proteins: extended characterization of an old gifted family
Published in Scientific reports (17-11-2016)“…The " 7 kDa DNA-binding " family, also known as the Sul7d family, is composed of chromatin proteins from the Sulfolobales archaeal order. Among them, Sac7d and…”
Get full text
Journal Article