Search Results - "Kaliberov, Sergey A."

Experimental cancer therapy using restoration of NAD+-linked 15-hydroxyprostaglandin dehydrogenase expression by Kaliberova, Lyudmila N, Kusmartsev, Sergei A, Krendelchtchikova, Valentina, Stockard, Cecil R, Grizzle, William E, Buchsbaum, Donald J, Kaliberov, Sergey A

“…Preclinical and clinical evidence shows that cyclooxygenase-2 (Cox-2)-mediated prostaglandin E 2 (PGE 2 ) overexpression plays an important role in tumor…”
Get full text

Retargeted oncolytic adenovirus displaying a single variable domain of camelid heavy-chain-only antibody in a fiber protein by van Erp, Elisabeth A, Kaliberova, Lyudmila N, Kaliberov, Sergey A, Curiel, David T

“…Conditionally replicative adenoviruses are promising agents for oncolytic virotherapy. Various approaches have been attempted to retarget adenoviruses to…”
Get full text

Molecular chemotherapy of pancreatic cancer using novel mutant bacterial cytosine deaminase gene by Kaliberova, Lyudmila N, Della Manna, Debbie L, Krendelchtchikova, Valentina, Black, Margaret E, Buchsbaum, Donald J, Kaliberov, Sergey A

“…The combination of molecular chemotherapy with radiation therapy has the potential to become a powerful approach for treatment of pancreatic cancer. We have…”
Get full text

Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome by Wambach, Jennifer A, Yang, Ping, Wegner, Daniel J, Heins, Hillary B, Kaliberova, Lyudmila N, Kaliberov, Sergey A, Curiel, David T, White, Frances V, Hamvas, Aaron, Hackett, Brian P, Cole, F Sessions

“…Mutations in the ATP-binding cassette transporter A3 gene (ABCA3) result in severe neonatal respiratory distress syndrome and childhood interstitial lung…”
Get full text

Development of an adenovirus vector vaccine platform for targeting dendritic cells by Sharma, Piyush K., Dmitriev, Igor P., Kashentseva, Elena A., Raes, Geert, Li, Lijin, Kim, Samuel W., Lu, Zhi-Hong, Arbeit, Jeffrey M., Fleming, Timothy P., Kaliberov, Sergey A., Goedegebuure, S. Peter, Curiel, David T., Gillanders, William E.

“…Adenoviral (Ad) vector vaccines represent one of the most promising modern vaccine platforms, and Ad vector vaccines are currently being investigated in human…”
Get full text

Adenoviral targeting using genetically incorporated camelid single variable domains by Kaliberov, Sergey A, Kaliberova, Lyudmila N, Buggio, Maurizio, Tremblay, Jacqueline M, Shoemaker, Charles B, Curiel, David T

“…The unique ability of human adenovirus serotype 5 (Ad5) to accomplish efficient transduction has allowed the use of Ad5-based vectors for a range of gene…”
Get full text

Retargeting of gene expression using endothelium specific hexon modified adenoviral vector by Kaliberov, Sergey A, Kaliberova, Lyudmila N, Hong Lu, Zhi, Preuss, Meredith A, Barnes, Justin A, Stockard, Cecil R, Grizzle, William E, Arbeit, Jeffrey M, Curiel, David T

“…Abstract Adenovirus serotype 5 (Ad5) vectors are well suited for gene therapy. However, tissue-selective transduction by systemically administered Ad5-based…”
Get full text

Gene delivery and gene therapy of prostate cancer by Kaliberov, Sergey A, Buchsbaum, Donald J

“…Surgery, radiation or hormonal therapy are not adequate to control prostate cancer. Clearly, other novel treatment approaches, such as gene therapy, for…”
Get more information

Adenovirus-mediated FLT1-targeted proapoptotic gene therapy of human prostate cancer by Kaliberov, Sergey A, Kaliberova, Lyudmila N, Stockard, Cecil R, Grizzle, William E, Buchsbaum, Donald J

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) is of particular interest in the development of prostate carcinoma therapeutics as it…”
Get full text

Adenovirus-Mediated Transfer of BAX Driven by the Vascular Endothelial Growth Factor Promoter Induces Apoptosis in Lung Cancer Cells by Kaliberov, Sergey A, Buchsbaum, Donald J, Gillespie, G.Yancey, Curiel, David T, Arafat, Waleed O, Carpenter, Mark, Stackhouse, Murray A

“…Apoptosis induction is a promising approach for cancer gene therapy. Bax is a death-promoting member of the Bcl2 family of genes that are intimately involved…”
Get full text

947. Gene Directed Enzyme/Prodrug Therapy of Human Glioma Xenografts Using Mutant Escherichia coli Cytosine Deaminase by Kaliberov, Sergey A., Krendelchtchikova, Valentina, Manna, Debbie Della, Sellers, Jeffrey C., Kaliberova, Lyudmila N., Black, Margaret E., Buchsbaum, Donald J.

“…Combined treatment using suicide gene therapy and radiation therapy has the potential to become a powerful new method of cancer therapy. We have developed a…”
Get full text

Cancer Treatment with Gene Therapy and Radiation Therapy by Kaliberov, Sergey A., Buchsbaum, Donald J.

“…Radiation therapy methods have evolved remarkably in recent years which have resulted in more effective local tumor control with negligible toxicity of…”
Get full text

Experimental virotherapy of chemoresistant pancreatic carcinoma using infectivity-enhanced fiber-mosaic oncolytic adenovirus by Kaliberov, S A, Kaliberova, L N, Buchsbaum, D J, Curiel, D T

“…Pancreatic cancer is a significant clinical problem and novel therapeutic approaches are desperately needed. Recent advances in conditionally replicative…”
Get full text

Chapter seven--Cancer treatment with gene therapy and radiation therapy by Kaliberov, Sergey A, Buchsbaum, Donald J

“…Radiation therapy methods have evolved remarkably in recent years which have resulted in more effective local tumor control with negligible toxicity of…”
Get full text