Search Results - "Kalff, Jorg C."
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Preoperative combined mechanical and oral antibiotic bowel preparation for preventing complications in elective colorectal surgery
Published in Cochrane database of systematic reviews (07-02-2023)“…The success of elective colorectal surgery is mainly influenced by the surgical procedure and postoperative complications. The most serious complications…”
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Life on the line - Incidence and management of central venous catheter complications in intestinal failure
Published in Clinical nutrition (Edinburgh, Scotland) (01-06-2024)“…Loss of venous access is threatening for patients with intestinal failure (IF) under long-term parenteral nutrition (PN). We aimed to identify the incidence of…”
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Expression of the large amino acid transporter SLC7A5/LAT1 on immune cells is enhanced in primary sclerosing cholangitis-associated cholangiocarcinoma and correlates with poor prognosis in cholangiocarcinoma
Published in Human pathology (01-11-2024)“…Biliary tract cancers (BTC) are rare lethal malignancies arising along the biliary tree. Unfortunately, effective therapeutics are lacking and the prognosis…”
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4
Microbiota-dependent presence of murine enteric glial cells requires myeloid differentiation primary response protein 88 signaling
Published in Journal of biosciences (10-02-2023)“…Enteric glial cells (EGCs) were shown to maintain the barrier integrity and immune homeostasis of the bowel. Postnatally, EGCs develop from progenitor cells…”
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A novel P2X2‐dependent purinergic mechanism of enteric gliosis in intestinal inflammation
Published in EMBO molecular medicine (11-01-2021)“…Enteric glial cells (EGC) modulate motility, maintain gut homeostasis, and contribute to neuroinflammation in intestinal diseases and motility disorders…”
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β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery
Published in Journal of neuroinflammation (08-11-2023)“…Abstract Background Enteric glia contribute to the pathophysiology of various intestinal immune-driven diseases, such as postoperative ileus (POI), a motility…”
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Normothermic Machine Perfusion (NMP) of the Liver – Current Status and Future Perspectives
Published in Annals of transplantation (24-08-2021)“…A shortage of available organs for liver transplantation has led transplant surgeons and researchers to seek for innovative approaches in hepatoprotection and…”
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Prognostic factors for the long term outcome after surgical celiac artery decompression in MALS
Published in Orphanet journal of rare diseases (23-10-2023)“…Abstract Background The median arcuate ligament syndrome (MALS) is a rare disease caused by compression of the celiac artery (ORPHA: 293208). Surgical…”
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Clinical Performance of CEA, CA19-9, CA15-3, CA125 and AFP in Gastrointestinal Cancer Using LOCI™-based Assays
Published in Anticancer research (01-01-2017)“…Few data are available regarding the clinical performance of LOCI™-based tumor marker assays. We investigated the diagnostic power of carcinogenic antigen,…”
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The impact of lenvatinib on sarcopenia in patients with advanced unresectable hepatocellular carcinoma
Published in Scientific reports (27-09-2024)“…Lenvatinib is a multiple receptor tyrosine kinase inhibitor (TKI) approved for first-line treatment of patients with unresectable hepatocellular carcinoma…”
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Preoperative TIPS prevents the development of postoperative acute-on-chronic liver failure in patients with high CLIF-C AD score
Published in JHEP reports (01-03-2022)“…Acute-on-chronic liver failure (ACLF) is a syndrome associated with organ failure and high short-term mortality. Recently, the role of surgery as a…”
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Surgical treatment of mechanical bowel obstruction: characteristics and outcomes of geriatric patients compared to a younger cohort
Published in International journal of colorectal disease (01-06-2022)“…Purpose Mechanical bowel obstruction (MBO) is one of the most common indications for emergency surgery. Recent research justifies the method of attempting…”
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Impact of regular additional endobiliary radiofrequency ablation on survival of patients with advanced extrahepatic cholangiocarcinoma under systemic chemotherapy
Published in Scientific reports (19-01-2022)“…Prognosis of patients with advanced extrahepatic cholangiocarcinoma (eCCA) is poor. The current standard first-line treatment is systemic chemotherapy (CT)…”
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Diagnostic Potential of Exosomal microRNAs in Colorectal Cancer
Published in Diagnostics (Basel) (08-06-2022)“…Background: Despite the significance of colonoscopy for early diagnosis of colorectal adenocarcinoma (CRC), population-wide screening remains challenging,…”
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A role for 12/15‐lipoxygenase‐derived proresolving mediators in postoperative ileus: protectin DX‐regulated neutrophil extravasation
Published in Journal of leukocyte biology (01-02-2016)“…Resolution of POI involves monocytotic 12/15‐LOX activity and generation of PDX, resulting in reduction of neutrophil infiltration into the postoperative bowel…”
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DNA Methylation of PITX2 and PANCR Is Prognostic for Overall Survival in Patients with Resected Adenocarcinomas of the Biliary Tract
Published in PloS one (31-10-2016)“…Biliary tract cancers (BTC) are rare but highly aggressive malignant epithelial tumors. In order to improve the outcome in this lethal disease, novel…”
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Sympathetic Innervation Modulates Mucosal Immune Homeostasis and Epithelial Host Defense
Published in Cells (Basel, Switzerland) (01-08-2022)“…Intestinal mucosal cells, such as resident macrophages and epithelial cells, express adrenergic receptors and are receptive to norepinephrine, the primary…”
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T helper type 1 memory cells disseminate postoperative ileus over the entire intestinal tract
Published in Nature medicine (01-12-2010)“…One complication arising from gastrointestinal surgery is ileus, in which local manipulation of the intestine leads to dysmotility and paralysis of the entire…”
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Immersive collaborative virtual reality for case-based graduate student teaching in thoracic surgery: A piloting study
Published in Surgery open science (01-12-2024)“…In medical education various non-digital teaching methods are established. However, studies have proven that the immersive character of virtual reality (VR)…”
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Clinically Relevant Pancreatic Fistula after Pancreaticoduodenectomy: How We Do It
Published in Biology (Basel, Switzerland) (22-01-2023)“…(1) Background: This study's goals were to investigate possible risk factors for clinically relevant postoperative pancreatic fistula (POPF) grade B/C…”
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