Search Results - "Kaleja, Patrick"

Combination of SCX Fractionation and Charge-Reversal Derivatization Facilitates the Identification of Nontryptic Peptides in C‑Terminomics by Kaleja, Patrick, Helbig, Andreas O, Tholey, Andreas

“…The proteome wide, mass spectrometry based identification of protein C-termini is hampered by factors such as poor ionization efficiencies, low yielding…”
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Comparative Analysis of Extracellular Vesicles from Cytotoxic CD8 + αβ T Cells and γδ T Cells by Griesel, Lisa, Kaleja, Patrick, Tholey, Andreas, Lettau, Marcus, Janssen, Ottmar

“…Although belonging to different branches of the immune system, cytotoxic CD8 αβ T cells and γδ T cells utilize common cytolytic effectors including FasL,…”
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Analysis of Cytotoxic Granules and Constitutively Produced Extracellular Vesicles from Large Granular Lymphocytic Leukemia Cell Lines by Ploeger, Lara, Kaleja, Patrick, Tholey, Andreas, Lettau, Marcus, Janssen, Ottmar

“…Large granular lymphocyte leukemias (LGLLs) are rare lymphoproliferative malignancies caused by clonal expansion of granular lymphocytes. T-cell LGLL and…”
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Alveolar-Capillary Barrier Protection In Vitro: Lung Cell Type-Specific Effects and Molecular Mechanisms Induced by 1α, 25-Dihydroxyvitamin D3 by Xiong, Junyu, Kaleja, Patrick, Ückert, Larissa, Nezaratizadeh, Niloufar, Krantz, Stefanie, Krause, Martin Friedrich, Fitschen-Oestern, Stefanie, Seekamp, Andreas, Cassidy, Liam, Tholey, Andreas, Fuchs, Sabine

“…Low serum levels of 1α, 25-dihydroxyvitamin D3 (VD3) are associated with a higher mortality in trauma patients with sepsis or ARDS. However, the molecular…”
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Shedding light on both ends: An update on analytical approaches for N- and C-terminomics by Koudelka, Tomas, Winkels, Konrad, Kaleja, Patrick, Tholey, Andreas

“…Though proteases were long regarded as nonspecific degradative enzymes, over time, it was recognized that they also hydrolyze peptide bonds very specifically…”
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Evaluation and improvement of protein extraction methods for analysis of skin proteome by noninvasive tape stripping by Kaleja, Patrick, Emmert, Hila, Gerstel, Ulrich, Weidinger, Stephan, Tholey, Andreas

“…Analysis of the human skin proteome is key to understand molecular mechanisms maintaining health or leading to diseases of this important organ. For minimal…”
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The intracellular proteome of the gut bacterium Bacteroides thetaiotaomicron is widely unaffected by a switch from glucose to sucrose as main carbohydrate source by Genth, Jerome, Kaleja, Patrick, Treitz, Christian, Schäfer, Kathrin, Graspeuntner, Simon, Rupp, Jan, Tholey, Andreas

“…Bacteroides thetaiotaomicron is a gram negative bacterium within the human gut microbiome that metabolizes a wide range of dietary and mucosal polysaccharides…”
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