Search Results - "Kaldvee, Bret"
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Hyperproliferation is the main driver of metabolomic changes in psoriasis lesional skin
Published in Scientific reports (20-02-2020)“…Systematic understanding of the metabolite signature of diseases may lead to a closer understanding of the disease pathogenesis and ultimately to the…”
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Metabolomic Differences between the Skin and Blood Sera of Atopic Dermatitis and Psoriasis
Published in International journal of molecular sciences (01-11-2022)“…Atopic dermatitis (AD) and psoriasis (PS) are common chronic inflammatory dermatoses. Although the differences at the intercellular and intracellular signaling…”
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Metabolomic Analysis of Skin Biopsies from Patients with Atopic Dermatitis Reveals Hallmarks of Inflammation, Disrupted Barrier Function and Oxidative Stress
Published in Acta dermato-venereologica (24-02-2021)“…The main objectives of this study were to characterize the metabolomic profile of lesional skin of patients with atopic dermatitis, and to compare it with non-…”
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SERPINB2 and miR‐146a/b are coordinately regulated and act in the suppression of psoriasis‐associated inflammatory responses in keratinocytes
Published in Experimental dermatology (01-01-2020)“…Psoriasis is a chronic inflammatory skin disease with numerous involved factors. miR‐146a and miR‐146b (miR‐146a/b) are anti‐inflammatory miRNAs that are…”
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miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis
Published in Journal of investigative dermatology (01-09-2017)“…miR-146a inhibits inflammatory responses in human keratinocytes and in different mouse models of skin inflammation. Little is known about the role of miR-146b…”
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miR‐10a‐5p is increased in atopic dermatitis and has capacity to inhibit keratinocyte proliferation
Published in Allergy (Copenhagen) (01-11-2019)“…Background miR‐10a‐5p has been shown to regulate cancer cell proliferation and invasiveness and endothelial cell inflammatory responses. The function of…”
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