Search Results - "Kalbacher, H."

Characterization of the ubiquitin-proteasome system in bortezomib-adapted cells by Rückrich, T, Kraus, M, Gogel, J, Beck, A, Ovaa, H, Verdoes, M, Overkleeft, H S, Kalbacher, H, Driessen, C

“…Resistance towards the proteasome inhibitor bortezomib is poorly understood. We adapted the HL-60, ARH-77 and AMO-1 cell lines (myeloid leukemia, plasmocytoid…”
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Human Platelets Take up Anti-VEGF Agents by Sobolewska, B., Fehrenbacher, B., Münzer, P., Kalbacher, H., Geue, S., Stellos, Konstantinos, Schaller, M., Ziemssen, F.

“…Purpose. Growing evidence suggests different systemic exposure of anti-vascular endothelial growth factor (anti-VEGF) agents with repeated intravitreal…”
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Naturally Processed Dermcidin-Derived Peptides Do Not Permeabilize Bacterial Membranes and Kill Microorganisms Irrespective of Their Charge by STEFFEN, H, RIEG, S, WIEDEMANN, I, KALBACHER, H, DEEG, M, SAHL, H.-G, PESCHEL, A, GÖTZ, F, GARBE, C, SCHITTEK, B

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Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme by LIEBNER, S, FISCHMANN, A, RASCHER, G, DUFFNER, F, GROTE, E.-H, KALBACHER, H, WOLBURG, H

“…The aim of the study was to characterize the interendothelial junctions in tumor microvessels of five cases of human glioblastoma multiforme. In addition to…”
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Dermcidin is constitutively produced by eccrine sweat glands and is not induced in epidermal cells under inflammatory skin conditions by Rieg, S., Garbe, C., Sauer, B., Kalbacher, H., Schittek, B.

“…Summary Background  Antimicrobial peptides (AMPs) are important effector molecules of innate immunity, protecting epithelial surfaces of multicellular…”
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Two classes of outer hair cells along the tonotopic axis of the cochlea by Engel, J., Braig, C., Rüttiger, L., Kuhn, S., Zimmermann, U., Blin, N., Sausbier, M., Kalbacher, H., Münkner, S., Rohbock, K., Ruth, P., Winter, H., Knipper, M.

“…The molecular basis of high versus low frequency hearing loss and the differences in the sensitivity of outer hair cells depending on their cochlear…”
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Human gastric TFF2 peptide contains an N-linked fucosylated N,N'-diacetyllactosediamine (LacdiNAc) oligosaccharide by Hanisch, Franz-Georg, Ragge, Hubert, Kalinski, Thomas, Meyer, Frank, Kalbacher, Hubert, Hoffmann, Werner

“…In the human stomach, the peptide trefoil factor family 2 (TFF2) is secreted together with the mucin MUC6 by mucous neck cells (MNCs) and antral gland cells…”
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Indirect coating of RGD peptides using a poly-L-lysine spacer enhances jaw periosteal cell adhesion, proliferation, and differentiation into osteogenic tissue by Ardjomandi, N., Klein, C., Kohler, K., Maurer, A., Kalbacher, H., Niederländer, J., Reinert, S., Alexander, D.

“…The aim of our study was to generate a biofunctionalized, three‐dimensional (3D) biomaterial to enhance jaw periosteal cell (JPC) adhesion and differentiation…”
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1078 Prothymosin Alpha and Its Carboxy-terminal Decapeptide ProTalpha(100-109) Induce Th1-type Tumor-specific Immune Responses by Ioannou, K, Derhovanessian, E, Samara, P, Voutsas, I.F, Kalbacher, H, Voelter, W, Pawelec, G, Tsitsilonis, O.E

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Trefoil Factor Family-Peptides Promote Migration of Human Bronchial Epithelial Cells . Synergistic Effect with Epidermal Growth Factor by Oertel, Martin, Graness, Angela, Thim, Lars, Buhling, Frank, Kalbacher, Hubert, Hoffmann, Werner

“…A process termed "restitution" enables rapid repair of the respiratory epithelium by migration of neighbouring cells. Mucin-associated TFF-peptides (formerly…”
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Cellular uptake of cationic gadolinium-DOTA peptide conjugates with and without N-terminal myristoylation by Sturzu, A, Klose, U, Echner, H, Beck, A, Gharabaghi, A, Kalbacher, H, Heckl, S

“…Cellular and nuclear uptake of dual labelled conjugates could be of great value for chemotherapy and cancer diagnostics. Therefore we designed conjugates in…”
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Resistance to dermcidin-derived peptides is independent of bacterial protease activity by Senyürek, I, Döring, G, Kalbacher, H, Deeg, M, Peschel, A, Wolz, C, Schittek, B

“…Abstract Dermcidin (DCD) is an antimicrobial peptide constitutively expressed in eccrine sweat glands in human skin. By post-secretory proteolytic processing…”
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Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB104, DQ8 Type 1 diabetes by DURINOVIC-BELLO, I, SCHLOSSER, M, KARGES, W, BOEHM, B. O, RIEDL, M, MAISEL, N, ROSINGER, S, KALBACHER, H, DEEG, M, ZIEGLER, M, ELLIOTT, J, ROEP, B. O

“…Preproinsulin is a target T cell autoantigen in human Type 1 diabetes. This study analyses the phenotype and epitope recognition of preproinsulin reactive T…”
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Enhanced T cell responsiveness to citrulline-containing myelin basic protein in multiple sclerosis patients by Tranquill, L.R., Cao, L., Ling, N.C., Kalbacher, H., Martin, R.M., Whitaker, J.N.

“…Myelin basic protein (MBP), a candidate autoantigen in multiple sclerosis (MS), exists in different isoforms and charge isomers generated by differential…”
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Ligand motifs of HLA-DRB50101 and DRB11501 molecules delineated from self-peptides by Vogt, AB, Kropshofer, H, Kalbacher, H, Kalbus, M, Rammensee, HG, Coligan, JE, Martin, R

“…Antigenic peptides are presented to CD4+ T cells by MHC class II molecules via a highly polymorphic peptide-binding groove. The two HLA-DR alleles isotypically…”
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Biotinylated fluorescent peptide substrates for the sensitive and specific determination of cathepsin D activity by Baechle, D., Cansier, A., Fischer, R., Brandenburg, J., Burster, T., Driessen, C., Kalbacher, H.

“…Cathepsin D (CatD) is a member of the mammalian aspartic protease family and is involved in cellular protein degradation and in several pathological processes…”
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Tfg (Trk fused gene) is a Carma-1/IKKγ interacting protein involved in CD40-induced canonical NF-κB signaling by Grohmann, M, Hermann, I, Hampel, M, Karas, M, Kalbacher, H, Jäck, HM, Mielenz, D

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Characterization of legumain by Schwarz, Gerold, Brandenburg, Jens, Reich, Michael, Burster, Timo, Driessen, Christoph, Kalbacher, Hubert

“…The mammalian legumain, also called asparaginyl endopeptidase (AEP), is critically involved in the processing of bacterial antigens for MHC class II…”
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Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages by Schmid, Heide, Sauerbrei, Ramona, Schwarz, Gerold, Weber, Ekkehard, Kalbacher, Hubert, Driessen, Christoph

“…Endosomal and lysosomal fractions of human monocytes/macrophages prepared from buffy coats were analyzed for activities of cathepsins B, L and S, and…”
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A continuous sequence of more than 70 amino acids is essential for antibody binding to the dominant antigenic site of glycoprotein gp58 of human cytomegalovirus by WAGNER, B, KROPFF, B, KALBACHER, H, BRITT, W, SUNDQVIST, V.-A, ÖSTBERG, L, MACH, M

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