Search Results - "Kalajzić, Ivo"

What do we know about bone morphogenetic proteins and osteochondroprogenitors in inflammatory conditions? by Lukač, Nina, Katavić, Vedran, Novak, Sanja, Šućur, Alan, Filipović, Maša, Kalajzić, Ivo, Grčević, Danka, Kovačić, Nataša

“…Osteochondroprogenitors are crucial for embryonic bone development and postnatal processes such as bone repair in response to fracture injury, and their…”
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Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models by Šisl, Dino, Planinić, Pavao, Novak, Sanja, Filipović, Maša, Flegar, Darja, Šućur, Alan, Turčić, Petra, Kovačić, Nataša, Kalajzić, Ivo, Grčević, Danka, Kelava, Tomislav

“…Recent research suggests a possible role of Notch signaling pathway in development of liver fibrosis, but exact cellular and molecular mechanisms are still not…”
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The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair by Grčević, Danka, Sironi, Marina, Valentino, Sonia, Deban, Livija, Cvija, Hrvoje, Inforzato, Antonio, Kovačić, Nataša, Katavić, Vedran, Kelava, Tomislav, Kalajzić, Ivo, Mantovani, Alberto, Bottazzi, Barbara

“…Pentraxin 3 (PTX3) is an inflammatory mediator acting as a fluid-phase pattern recognition molecule and playing an essential role in innate immunity and matrix…”
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Heterogeneity of murine periosteum progenitors involved in fracture healing by Matthews, Brya G, Novak, Sanja, Sbrana, Francesca V, Funnell, Jessica L, Cao, Ye, Buckels, Emma J, Grcevic, Danka, Kalajzic, Ivo

“…The periosteum is the major source of cells involved in fracture healing. We sought to characterize progenitor cells and their contribution to bone fracture…”
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Quiescent Bone Lining Cells Are a Major Source of Osteoblasts During Adulthood by Matic, Igor, Matthews, Brya G., Wang, Xi, Dyment, Nathaniel A., Worthley, Daniel L., Rowe, David W., Grcevic, Danka, Kalajzic, Ivo

“…The in vivo origin of bone‐producing osteoblasts is not fully defined. Skeletal stem cells, a population of mesenchymal stem cells resident in the bone marrow…”
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CD13 is a critical regulator of cell–cell fusion in osteoclastogenesis by Ghosh, Mallika, Kelava, Tomislav, Madunic, Ivana Vrhovac, Kalajzic, Ivo, Shapiro, Linda H.

“…The transmembrane aminopeptidase CD13 is highly expressed in cells of the myeloid lineage, regulates dynamin-dependent receptor endocytosis and recycling and…”
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Exploiting endogenous fibrocartilage stem cells to regenerate cartilage and repair joint injury by Embree, Mildred C., Chen, Mo, Pylawka, Serhiy, Kong, Danielle, Iwaoka, George M., Kalajzic, Ivo, Yao, Hai, Shi, Chancheng, Sun, Dongming, Sheu, Tzong-Jen, Koslovsky, David A., Koch, Alia, Mao, Jeremy J.

“…Tissue regeneration using stem cell-based transplantation faces many hurdles. Alternatively, therapeutically exploiting endogenous stem cells to regenerate…”
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CD51 labels periosteal injury-responsive osteoprogenitors by Cao, Ye, Kalajzic, Ivo, Matthews, Brya G

“…The periosteum is a critical source of skeletal stem and progenitor cells (SSPCs) that form callus tissue in response to injury. There is yet to be a consensus…”
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Sex and genetic factors determine osteoblastic differentiation potential of murine bone marrow stromal cells by Zanotti, Stefano, Kalajzic, Ivo, Aguila, Hector Leonardo, Canalis, Ernesto

“…Sex and genetic factors determine skeletal mass, and we tested whether bone histomorphometric parameters were sexually dimorphic in femurs from 1 to 6 month…”
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Cell line IDG‐SW3 replicates osteoblast‐to‐late‐osteocyte differentiation in vitro and accelerates bone formation in vivo by Woo, Stacey M, Rosser, Jennifer, Dusevich, Vladimir, Kalajzic, Ivo, Bonewald, Lynda F

“…Osteocytes are the most abundant cells in bone yet are the most challenging to study because they are embedded in a mineralized matrix. We generated a clonal…”
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Vitamin C epigenetically controls osteogenesis and bone mineralization by Thaler, Roman, Khani, Farzaneh, Sturmlechner, Ines, Dehghani, Sharareh S., Denbeigh, Janet M., Zhou, Xianhu, Pichurin, Oksana, Dudakovic, Amel, Jerez, Sofia S., Zhong, Jian, Lee, Jeong-Heon, Natarajan, Ramesh, Kalajzic, Ivo, Jiang, Yong-hui, Deyle, David R., Paschalis, Eleftherios P., Misof, Barbara M., Ordog, Tamas, van Wijnen, Andre J.

“…Vitamin C deficiency disrupts the integrity of connective tissues including bone. For decades this function has been primarily attributed to Vitamin C as a…”
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Lineage tracing of resident tendon progenitor cells during growth and natural healing by Dyment, Nathaniel A, Hagiwara, Yusuke, Matthews, Brya G, Li, Yingcui, Kalajzic, Ivo, Rowe, David W

“…Unlike during embryogenesis, the identity of tissue resident progenitor cells that contribute to postnatal tendon growth and natural healing is poorly…”
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In Vivo Fate Mapping Identifies Mesenchymal Progenitor Cells by Grcevic, Danka, Pejda, Slavica, Matthews, Brya G., Repic, Dario, Wang, Liping, Li, Haitao, Kronenberg, Mark S., Jiang, Xi, Maye, Peter, Adams, Douglas J., Rowe, David W., Aguila, Hector L., Kalajzic, Ivo

“…Adult mesenchymal progenitor cells have enormous potential for use in regenerative medicine. However, the true identity of the progenitors in vivo and their…”
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Hematopoietic and stromal DMP1-Cre labeled cells form a unique niche in the bone marrow by Root, Sierra H., Matthews, Brya G., Torreggiani, Elena, Aguila, Hector Leonardo, Kalajzic, Ivo

“…Skeletogenesis and hematopoiesis are interdependent. Niches form between cells of both lineages where microenvironmental cues support specific lineage…”
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In vitro and in vivo approaches to study osteocyte biology by Kalajzic, Ivo, Matthews, Brya G, Torreggiani, Elena, Harris, Marie A, Divieti Pajevic, Paola, Harris, Stephen E

“…Abstract Osteocytes, the most abundant cell population of the bone lineage, have been a major focus in the bone research field in recent years. This population…”
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Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts by Krevvata, Maria, Silva, Barbara C., Manavalan, John S., Galan-Diez, Marta, Kode, Aruna, Matthews, Brya Grace, Park, David, Zhang, Chiyuan A., Galili, Naomi, Nickolas, Thomas L., Dempster, David W., Dougall, William, Teruya-Feldstein, Julie, Economides, Aris N., Kalajzic, Ivo, Raza, Azra, Berman, Ellin, Mukherjee, Siddhartha, Bhagat, Govind, Kousteni, Stavroula

“…The bone marrow niche is thought to act as a permissive microenvironment required for emergence or progression of hematologic cancers. We hypothesized that…”
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A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing by Doherty, Laura, Yu, Jungeun, Wang, Xi, Hankenson, Kurt D, Kalajzic, Ivo, Sanjay, Archana

“…Insufficient and delayed fracture healing remain significant public health problems with limited therapeutic options. Phosphoinositide 3-kinase (PI3K)…”
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Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair by Novak, Sanja, Roeder, Emilie, Kalinowski, Judith, Jastrzebski, Sandra, Aguila, Hector L., Lee, Sun-Kyeong, Kalajzic, Ivo, Lorenzo, Joseph A.

“…Osteoclasts (OC) originate from either bone marrow (BM)–resident or circulating myeloid OC progenitors (OCP) expressing the receptor CX3CR1. Multiple lines of…”
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Identification of differentially expressed genes between osteoblasts and osteocytes by Paic, Frane, Igwe, John C, Nori, Ravi, Kronenberg, Mark S, Franceschetti, Tiziana, Harrington, Patrick, Kuo, Lynn, Shin, Dong-Guk, Rowe, David W, Harris, Stephen E, Kalajzic, Ivo

“…Abstract Osteocytes represent the most abundant cellular component of mammalian bones with important functions in bone mass maintenance and remodeling. To…”
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Neuropeptide Y is expressed by osteocytes and can inhibit osteoblastic activity by Igwe, John C., Jiang, Xi, Paic, Frane, Ma, Li, Adams, Douglas J., Baldock, Paul A., Pilbeam, Carol C., Kalajzic, Ivo

“…Osteocytes are the most abundant osteoblast lineage cells within the bone matrix. They respond to mechanical stimulation and can participate in the release of…”
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