Search Results - "Kaku Tsuruzoe"

Adenosine Monophosphate-Activated Protein Kinase Suppresses Vascular Smooth Muscle Cell Proliferation Through the Inhibition of Cell Cycle Progression by Igata, Motoyuki, Motoshima, Hiroyuki, Tsuruzoe, Kaku, Kojima, Kanou, Matsumura, Takeshi, Kondo, Tatsuya, Taguchi, Tetsuya, Nakamaru, Kazuhiko, Yano, Miyuki, Kukidome, Daisuke, Matsumoto, Kazuya, Toyonaga, Tetsushi, Asano, Tomoichiro, Nishikawa, Takeshi, Araki, Eiichi

“…Vascular smooth muscle cell (VSMC) proliferation is a critical event in the development and progression of vascular diseases, including atherosclerosis. We…”
Get full text

Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal–Regulating Kinase 1 on Insulin Signaling by IMOTO, Koujiro, KUKIDOME, Daisuke, MATSUMURA, Takeshi, ICHIJO, Hidenori, ARAKI, Eiichi, NISHIKAWA, Takeshi, MATSUHISA, Takako, SONODA, Kazuhiro, FNJISAWA, Kazuo, YANO, Miyuki, MOTOSHIMA, Hiroyuki, TAGUCHI, Tetsuya, TSURUZOE, Kaku

“…Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal–Regulating Kinase 1 on Insulin Signaling Koujiro Imoto 1 , Daisuke Kukidome 1 , Takeshi…”
Get full text

An acylic polyisoprenoid derivative, geranylgeranylacetone protects against visceral adiposity and insulin resistance in high-fat-fed mice by Adachi, Hironori, Kondo, Tatsuya, Ogawa, Rei, Sasaki, Kazunari, Morino-Koga, Saori, Sakakida, Michiharu, Kawashima, Junji, Motoshima, Hiroyuki, Furukawa, Noboru, Tsuruzoe, Kaku, Miyamura, Nobuhiro, Kai, Hirofumi, Araki, Eiichi

“…Induction of heat shock protein (HSP)72 improves insulin resistance and obesity in diabetic animal models. Geranylgeranylacetone (GGA), known as an antiulcer…”
Get more information

Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice by Goto, Hideo, Nishikawa, Takeshi, Sonoda, Kazuhiro, Kondo, Tatsuya, Kukidome, Daisuke, Fujisawa, Kazuo, Yamashiro, Takeshi, Motoshima, Hiroyuki, Matsumura, Takeshi, Tsuruzoe, Kaku, Araki, Eiichi

“…We previously proposed that hyperglycemia-induced mitochondrial ROS overproduction is a key event in the development of diabetic complications. In this study,…”
Get full text

A Case of Ectopic Adrenocorticotropic Hormone-producing Pancreatic Neuroendocrine Tumor with Multiple Liver Metastases by KONDO, Tatsuya, MATSUYAMA, Rina, ASHIHARA, Hiroshi, MATSUO, Yasuto, SASAKI, Kazunari, GOTO, Rieko, ONO, Kaoru, TAKAKI, Yuki, HONDA, Yumi, IYAMA, Ken-ichi, KAWASHIMA, Junji, MOTOSHIMA, Hiroyuki, TSURUZOE, Kaku, MIYAMURA, Nobuhiro, ARAKI, Eiichi

“…Ectopic adrenocorticotropic hormone (ACTH) production by the pancreatic neuroendocrine tumor (p-NET) is relatively rare, and patients with this tumor show poor…”
Get full text

Effects of Olmesartan, an Angiotensin II Receptor Blocker, on Peripheral Insulin Sensitivity in Japanese Subjects with Type 2 Diabetes and Hypertension by Shimoda, Seiya, Goto, Rieko, Furukawa, Noboru, Tsuruzoe, Kaku, Kawashima, Junji, Iwashita, Shinsuke, Maeda, Takako, Ichimori, Shinji, Ichinose, Kenshi, Nishida, Kenro, Araki, Eiichi

“…Objective Several studies have assessed the efficacy of angiotensin receptor blockers (ARBs) on peripheral insulin sensitivity using the euglycemic…”
Get full text

The impact of Ca2+/calmodulin-dependent protein kinase II on insulin gene expression in MIN6 cells by Suefuji, Mihoshi, Furukawa, Noboru, Matsumoto, Kazuya, Oiso, Hiroshi, Shimoda, Seiya, Yoshinaga, Tomoaki, Matsuyama, Rina, Miyagawa, Katsutoshi, Kondo, Tatsuya, Kawashima, Junji, Tsuruzoe, Kaku, Araki, Eiichi

“…► Insulin gene promoter activity is downregulated by CaMKIIδ2 in MIN6 cells. ► The effects of CaMKIIδ2 are independent of glucose and membrane depolarization…”
Get full text

Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma by Igata, Motoyuki, Tsuruzoe, Kaku, Kawashima, Junji, Kukidome, Daisuke, Kondo, Tatsuya, Motoshima, Hiroyuki, Shimoda, Seiya, Furukawa, Noboru, Nishikawa, Takeshi, Miyamura, Nobuhiro, Araki, Eiichi

“…Summary Resistance to thyroid hormone (RTH) is a syndrome of reduced tissue responsiveness to thyroid hormones. RTH is majorly caused by mutations in the…”
Get full text

Insulin Receptor Substrate 3 (IRS-3) and IRS-4 Impair IRS-1- and IRS-2-Mediated Signaling by Tsuruzoe, Kaku, Emkey, Renee, Kriauciunas, Kristina M., Ueki, Kohjiro, Kahn, C. Ronald

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells by Nakamaru, Kazuhiko, Matsumoto, Kazuya, Taguchi, Tetsuya, Suefuji, Mihoshi, Murata, Yusuke, Igata, Motoyuki, Kawashima, Junji, Kondo, Tatsuya, Motoshima, Hiroyuki, Tsuruzoe, Kaku, Miyamura, Nobuhiro, Toyonaga, Tetsushi, Araki, Eiichi

“…The liver is one of the major target organs of insulin in which the expression of insulin receptor is abundant. We analyzed the effect of AICAR, an AMPK…”
Get full text

P1-23-6 HMG-CoA reductase inhibitors ameliorate insulin resistance trough PPARγ activation by Takeshi Matsumura, Norio Ishii, Hiroyuki Kinoshita, Hiroyuki Motoshima, Yusuke Murata, Kaku Tsuruzoe, Takeshi Nishikawa, Eiichi Araki

Get full text

Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas by TSURUZOE, K, ARAKI, E, MIYAZAKI, J.-I, SHICHIRI, M, FURUKAWA, N, SHIROTANI, T, MATSUMOTO, K, KANEKO, K, MOTOSHIMA, H, YOSHIZATO, K, SHIRAKAMI, A, KISHIKAWA, H

“…Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and…”
Get full text

Possible Involvement of Atypical Protein Kinase C (PKC) in Glucose-Sensitive Expression of the Human Insulin Gene: DNA-Binding Activity and Transcriptional Activity of Pancreatic and Duodenal Homeobox Gene-1 (PDX-1) Are Enhanced via Calphostin C-Sensitive but Phorbol 12-Myristate 13-Acetate (PMA) and Gö 6976-Insensitive Pathway by FURUKAWA, NOBORU, SHIROTANI, TETSUYA, ARAKI, EIICHI, KANEKO, KENGO, TODAKA, MIKIO, MATSUMOTO, KAZUYA, TSURUZOE, KAKU, MOTOSHIMA, HIROYUKI, YOSHIZATO, KAZUAKI, KISHIKAWA, HIDEKI, SHICHIRI, MOTOAKI

“…Pancreatic and duodenal homeobox gene-1(PDX-1) is a transcription factor which regulates the insulin gene expression. In this study, we tried to elucidate the…”
Get full text

A Case of Ectopic Adrenocorticotropic Hormone-producing Pancreatic Neuroendocrine Tumor with Multiple Liver Metastases by TATSUYA KONDO, RINA MATSUYAMA, HIROSHI ASHIHARA, YASUTO MATSUO, KAZUNARI SASAKI, RIEKO GOTO, KAORU ONO, YUKI TAKAKI, YUMI HONDA, KEN-ICHI IYAMA, JUNJI KAWASHIMA, HIROYUKI MOTOSHIMA, KAKU TSURUZOE, NOBUHIRO MIYAMURA, EIICHI ARAKI

“…Abstract. Ectopic adrenocorticotropic hormone (ACTH) production by the pancreatic neuroendocrine tumor (p-NET) is relatively rare, and patients with this tumor…”
Get full text

Cell-specific regulation of IRS-1 gene expression: Role of E box and C/EBP binding site in HepG2 cells and CHO cells by MATSUDA, K, ARAKI, E, YOSHIMURA, R, TSURUZOE, K, FURUKAWA, N, KANEKO, K, MOTOSHIMA, H, YOSHIZATO, K, KISHIKAWA, H, SHICHIRI, M

“…Insulin receptor substrate 1 (IRS-1) is one of the major substrates of insulin receptor tyrosine kinase and mediates multiple insulin signals downstream. We…”
Get full text

Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice by Tsutsumi, Atsuyuki, Motoshima, Hiroyuki, Kondo, Tatsuya, Kawasaki, Shuji, Matsumura, Takeshi, Hanatani, Satoko, Igata, Motoyuki, Ishii, Norio, Kinoshita, Hiroyuki, Kawashima, Junji, Taketa, Kayo, Furukawa, Noboru, Tsuruzoe, Kaku, Nishikawa, Takeshi, Araki, Eiichi

“…► Caloric restriction (CR) reduced the weight of ob/ob mice. ► CR reduced ER stress markers such as phosphorylated PERK and eIF2α in ob/ob mice. ► CR reduced…”
Get full text

Oxidized Low Density Lipoprotein Activates Peroxisome Proliferator-activated Receptor-α (PPARα) and PPARγ through MAPK-dependent COX-2 Expression in Macrophages by Taketa, Kayo, Matsumura, Takeshi, Yano, Miyuki, Ishii, Norio, Senokuchi, Takafumi, Motoshima, Hiroyuki, Murata, Yusuke, Kim-Mitsuyama, Shokei, Kawada, Teruo, Itabe, Hiroyuki, Takeya, Motohiro, Nishikawa, Takeshi, Tsuruzoe, Kaku, Araki, Eiichi

“…It has been reported that oxidized low density lipoprotein (Ox-LDL) can activate both peroxisome proliferator-activated receptor-α (PPARα) and PPARγ. However,…”
Get full text

Angptl 4 deficiency improves lipid metabolism, suppresses foam cell formation and protects against atherosclerosis by Adachi, Hironori, Fujiwara, Yukio, Kondo, Tatsuya, Nishikawa, Takeshi, Ogawa, Rei, Matsumura, Takeshi, Ishii, Norio, Nagai, Ryoji, Miyata, Keishi, Tabata, Mitsuhisa, Motoshima, Hiroyuki, Furukawa, Noboru, Tsuruzoe, Kaku, Kawashima, Junji, Takeya, Motohiro, Yamashita, Shizuya, Koh, Gou Young, Nagy, Andras, Suda, Toshio, Oike, Yuichi, Araki, Eiichi

“…Angiopoietin-like protein family 4 (Angptl 4) has been shown to regulate lipoprotein metabolism through the inhibition of lipoprotein lipase (LPL). We…”
Get full text

Possible Involvement of Atypical Protein Kinase C(PKC) in Glucose-Sensitive Expression of the Human Insulin Gene: DNA-Binding Activity and Transcriptional Activity of Pancreatic and Duodenal Homeobox Gene-1(PDX-1) Are Enhanced via Calphostin C-Sensitive but Phorbol 12-Myristate 13-Acetate(PMA) and Goe 6976-Insensitive Pathway by FURUKAWA, NOBORU, SHIROTANI, TETSUYA, ARAKI, EIICHI, KANEKO, KENGO, TODAKA, MIKIO, MATSUMOTO, KAZUYA, TSURUZOE, KAKU, MOTOSHIMA, HIROYUKI, YOSHIZATO, KAZUAKI, KISHIKAWA, HIDEKI, SHICHIRI, MOTOAKI

Get full text

Enhanced expression of PDX-1 and Ngn3 by exendin-4 during β cell regeneration in STZ-treated mice by Kodama, Shoko, Toyonaga, Tetsushi, Kondo, Tatsuya, Matsumoto, Kazuya, Tsuruzoe, Kaku, Kawashima, Junji, Goto, Hideo, Kume, Kazuhiko, Kume, Shoen, Sakakida, Michiharu, Araki, Eiichi

“…Progenitor cells exist in the adult pancreas and transform to endocrine cells in pathological conditions. To address the mechanism of β cell regeneration, mice…”
Get full text